hydrocortisone rectal (Rx)

Brand and Other Names:Anusol HC, Cortifoam, more...Anucort-HC, Peranex HC, Proctol, Proctomyxin, Proctosedyl, Proctosedyl Ointment, Xyralid RC, Cortenema
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

cream

  • 1%
  • 0.5%
  • 1%
  • 2%
  • 2.5%

enema

  • 100mg/60mL

foam

  • 10% (15g)

suppository

  • 25mg
  • 30mg

Ulcerative Proctitis

Application to distal rectum in patients who cannot retain steroid enemas

Foam

  • 1 applicatorful PR once daily or q12hr for 2-3 weeks, then every other day if necessary; use lowest dosage that maintains clinical response; discontinue if no proctologic improvement is noted after 2-3 weeks
  • 1 applicatorful = 900 mg; contains 90 mg hydrocortisone acetate (= 80 mg hydrocortisone)

Suspension

  • 1 enema at bedtime for 21 days or until remission is achieved; 2-3 months of therapy may be required; taper to discontinue long-term therapy; improvement in mucosal integrity may be preceded by clinical improvement

Safety and efficacy not established

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Adverse Effects

Frequency Not Defined

Burning

Dryness

Folliculitis

Hypopigmentation

Itching

Pain

Rectal bleeding

Secondary infection

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Warnings

Contraindications

Documented hypersensitivity

Systemic fungal infections

Ileostomy during immediate or early postoperative period

Obstruction, abscess, perforation, peritonitis, fresh intestinal anastomoses, extensive fistulas

Cautions

Always follow directions for use on product carton

Do not insert any part of aerosol container directly into anus

Sigmoidoscopy is recommended for judging treatment course, rather than symptomatic improvement

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Pregnancy & Lactation

Pregnancy category: C

Lactation: Use with caution

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

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Pharmacology

Mechanism of Action

Decreases inflammation by suppressing migration of polymorphonuclear leukocytes (PMNs) and reversing increased capillary permeability

Absorption

Absorption limited

Onset: 5-7 days

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Images

BRAND FORM. UNIT PRICE PILL IMAGE
Cortizone-10 topical
-
1 % gel
Cortizone-10 topical
-
1 % lotion
Cortizone-10 topical
-
1 % ointment
Cortizone-10 topical
-
1 % lotion
Cortizone-10 topical
-
1 % cream
Cortizone-10 topical
-
1 % cream
Proctozone-HC topical
-
2.5 % cream
Proctozone-HC topical
-
2.5 % cream
Cortizone-10 Plus topical
-
1 % cream
Anusol-HC topical
-
2.5 % cream
Proctosol HC topical
-
2.5 % cream
Scalacort topical
-
2 % lotion
Proctocort topical
-
1 % cream
Aquanil HC topical
-
1 % lotion
Cortaid topical
-
1 % cream
Texacort topical
-
2.5 % solution
ITCH-X topical
-
1-10 % liquid
ITCH-X topical
-
1-10 % gel
Ala-Cort topical
-
1 % cream
Cortenema rectal
-
100 mg/60 mL enema
Cortenema rectal
-
100 mg/60 mL enema
Ala-Scalp topical
-
2 % lotion
Anusol-HC rectal
-
25 mg suppos
Anusol-HC rectal
-
25 mg suppos
Alkindi Sprinkle oral
-
0.5 mg capsule
Alkindi Sprinkle oral
-
5 mg capsule
Procto-Med HC topical
-
2.5 % cream
Procto-Pak topical
-
1 % cream
Pramosone topical
-
2.5-1 % lotion
Pramosone topical
-
1-1 % cream
Pramosone topical
-
2.5-1 % cream
Pramosone topical
-
2.5-1 % cream
Pramosone topical
-
1-1 % lotion
Pramosone topical
-
1-1 % lotion
Pramosone topical
-
2.5-1 % lotion
Pramosone topical
-
1-1 % cream
Cortef oral
-
20 mg tablet
Cortef oral
-
10 mg tablet
Cortef oral
-
5 mg tablet
hydrocortisone oral
-
10 mg tablet
hydrocortisone oral
-
20 mg tablet
hydrocortisone oral
-
5 mg tablet
hydrocortisone oral
-
20 mg tablet
hydrocortisone oral
-
5 mg tablet
hydrocortisone oral
-
10 mg tablet
hydrocortisone oral
-
10 mg tablet
hydrocortisone oral
-
5 mg tablet
hydrocortisone oral
-
20 mg tablet
hydrocortisone topical
-
1 % cream
hydrocortisone topical
-
1 % cream
hydrocortisone topical
-
2.5 % ointment
hydrocortisone topical
-
2.5 % ointment
hydrocortisone topical
-
1 % ointment
hydrocortisone topical
-
1 % cream
hydrocortisone topical
-
0.5 % cream
hydrocortisone topical
-
1 % cream
hydrocortisone topical
-
0.5 % cream
hydrocortisone topical
-
1 % ointment
hydrocortisone topical
-
1 % cream
hydrocortisone topical
-
1 % cream
hydrocortisone topical
-
1 % ointment
hydrocortisone topical
-
2.5 % cream
hydrocortisone topical
-
2.5 % lotion
hydrocortisone topical
-
2.5 % lotion
hydrocortisone topical
-
1 % ointment
hydrocortisone topical
-
2.5 % ointment
hydrocortisone topical
-
2.5 % ointment
hydrocortisone topical
-
2.5 % cream
hydrocortisone topical
-
1 % ointment
hydrocortisone topical
-
2.5 % lotion
hydrocortisone topical
-
0.5 % ointment
hydrocortisone topical
-
2.5 % cream
hydrocortisone topical
-
2.5 % cream
hydrocortisone topical
-
1 % ointment
hydrocortisone topical
-
1 % cream
hydrocortisone topical
-
2.5 % cream
hydrocortisone topical
-
1 % cream
hydrocortisone topical
-
1 % ointment
hydrocortisone topical
-
1 % cream
hydrocortisone topical
-
2.5 % cream
hydrocortisone topical
-
2.5 % cream
hydrocortisone topical
-
1 % cream
hydrocortisone topical
-
1 % cream
hydrocortisone topical
-
1 % cream
hydrocortisone topical
-
2.5 % cream
hydrocortisone topical
-
2.5 % cream
hydrocortisone topical
-
1 % cream
hydrocortisone topical
-
1 % lotion
hydrocortisone topical
-
1 % cream
hydrocortisone topical
-
1 % cream
hydrocortisone rectal
-
100 mg/60 mL enema
Cortisone (hydrocortisone) topical
-
1 % cream

Copyright © 2010 First DataBank, Inc.

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Patient Handout

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Patient Education
hydrocortisone topical

HYDROCORTISONE - TOPICAL

(HYE-droe-KOR-ti-sone)

COMMON BRAND NAME(S): Aquanil HC, Cetacort, Cortaid, Hytone

USES: This medication is used to treat a variety of skin conditions (such as insect bites, poison oak/ivy, eczema, dermatitis, allergies, rash, itching of the outer female genitals, anal itching). Hydrocortisone reduces the swelling, itching, and redness that can occur in these types of conditions. This medication is a mild corticosteroid.

HOW TO USE: There are many hydrocortisone products available. Many can be purchased without a prescription. Some products require a prescription. Consult your doctor or pharmacist on the choice of the product that is best for you.Use this medication on the skin only. However, do not use it on the face or underarms unless directed to do so by your doctor. Some products are meant to be used on the scalp for various conditions. To correctly use these products, follow the directions on the product package.Wash and dry your hands before using. Clean and dry the affected area. If you are using the lotion or foam, shake it well just before using. If you are using the spray, check the product package to see if it needs to be shaken before each use. Apply a small amount of medication to the affected area and gently rub in, usually up to 4 times a day or as directed by your doctor or the product package. Dosage and length of treatment depends on the type of condition being treated. Do not bandage, cover, or wrap the area unless directed to do so by your doctor. If used in or near the diaper area on an infant, do not use tight-fitting diapers or plastic pants.After applying the medication, wash your hands, unless the hands are being treated. Avoid getting this medication in the eyes, nose, or mouth. If you get the medication in these areas, rinse with plenty of water. If irritation occurs or continues, contact your doctor right away.Use this medication only for the condition for which it was prescribed or a condition that is listed on the product package. Do not use it for longer than directed by the product package or your doctor.Tell your doctor if your condition lasts or gets worse after 7 days or if you think you may have a serious medical problem.

SIDE EFFECTS: Stinging, burning, irritation, dryness, or redness at the application site may occur. Acne, unusual hair growth, small red bumps on the skin (folliculitis), skin thinning/discoloration, or stretch marks may also occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.If the treated area starts to bleed, especially if you are using this product for anal itching, contact your doctor right away.A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using hydrocortisone, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (such as prednisone, triamcinolone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.If you have any health problems, consult your doctor or pharmacist before using this product.If you have itching of the outer female genitals with vaginal discharge, consult your doctor before using this product.Do not use if there is an infection or sore in the area to be treated. Skin infections can become worse when this medication is used. Tell your doctor promptly if redness, swelling, or irritation does not improve.Children may be more sensitive to the effects of too much corticosteroid medication. Consult your doctor for more details.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk when applied to the skin. Similar medications pass into breast milk when taken by mouth. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

OVERDOSE: This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

NOTES: Do not share this medication with others.If prescribed by your doctor, use this medication for your current condition only. Do not use it later for other skin problems unless told to do so by your doctor. A different medication may be necessary in those cases.Keep all regular medical and laboratory appointments.

MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

STORAGE: Refer to the storage information printed on the package. Protect from light and moisture. If you have any questions about storage, ask your pharmacist. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Information last revised October 2022. Copyright(c) 2022 First Databank, Inc.

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

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Tier Description
1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.