Indication-specific dosing for apacin, apazote de zorro, aposin anamu in combination, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.

Sections

Sections Anamu
Suggested Dosing
Suggested Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology

Suggested Dosing

1000-1500 mg PO BID or as directed by Mfr

Suggested Uses

Cancer, various infections

Efficacy

In vitro studies indicate cytotoxic effect on cancer cells

Animal studies indicate immunostimulatory and antiinfective effects

No clinical studies

Interaction Checker

Enter a drug name and Anamu

No Results

No Interactions Found

Interactions Found

Contraindicated

Serious - Use Alternative

Significant - Monitor Closely

Minor

All Interactions Sort By:

Contraindicated (0)

Serious - Use Alternative (0)

Monitor Closely (14)

antithrombin alfa
antithrombin alfa and anamu both increase anticoagulation. Use Caution/Monitor.
antithrombin III
antithrombin III and anamu both increase anticoagulation. Use Caution/Monitor.
argatroban
argatroban and anamu both increase anticoagulation. Use Caution/Monitor.
bemiparin
bemiparin and anamu both increase anticoagulation. Use Caution/Monitor.
bivalirudin
bivalirudin and anamu both increase anticoagulation. Use Caution/Monitor.
dabigatran
dabigatran and anamu both increase anticoagulation. Use Caution/Monitor.
dalteparin
dalteparin and anamu both increase anticoagulation. Use Caution/Monitor.
enoxaparin
enoxaparin and anamu both increase anticoagulation. Use Caution/Monitor.
fondaparinux
fondaparinux and anamu both increase anticoagulation. Use Caution/Monitor.
heparin
heparin and anamu both increase anticoagulation. Use Caution/Monitor.
phenindione
phenindione and anamu both increase anticoagulation. Use Caution/Monitor.
protamine
protamine and anamu both increase anticoagulation. Use Caution/Monitor.
reteplase
reteplase and anamu both increase anticoagulation. Use Caution/Monitor.
tenecteplase
tenecteplase and anamu both increase anticoagulation. Use Caution/Monitor.

Minor (79)

acarbose
anamu increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
aceclofenac
aceclofenac and anamu both increase anticoagulation. Minor/Significance Unknown.
acemetacin
acemetacin and anamu both increase anticoagulation. Minor/Significance Unknown.
agrimony
agrimony and anamu both increase anticoagulation. Minor/Significance Unknown.
alfalfa
alfalfa and anamu both increase anticoagulation. Minor/Significance Unknown.
American ginseng
American ginseng and anamu both increase anticoagulation. Minor/Significance Unknown.
aspirin
aspirin and anamu both increase anticoagulation. Minor/Significance Unknown.
aspirin rectal
aspirin rectal and anamu both increase anticoagulation. Minor/Significance Unknown.
aspirin/citric acid/sodium bicarbonate
aspirin/citric acid/sodium bicarbonate and anamu both increase anticoagulation. Minor/Significance Unknown.
celecoxib
celecoxib and anamu both increase anticoagulation. Minor/Significance Unknown.
chlorpropamide
anamu increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
choline magnesium trisalicylate
choline magnesium trisalicylate and anamu both increase anticoagulation. Minor/Significance Unknown.
cinnamon
anamu and cinnamon both increase anticoagulation. Minor/Significance Unknown.
cordyceps
anamu and cordyceps both increase anticoagulation. Minor/Significance Unknown.
danshen
anamu and danshen both increase anticoagulation. Minor/Significance Unknown.
devil's claw
anamu and devil's claw both increase anticoagulation. Minor/Significance Unknown.
diclofenac
diclofenac and anamu both increase anticoagulation. Minor/Significance Unknown.
diflunisal
diflunisal and anamu both increase anticoagulation. Minor/Significance Unknown.
dong quai
anamu and dong quai both increase anticoagulation. Minor/Significance Unknown.
epoprostenol
anamu and epoprostenol both increase anticoagulation. Minor/Significance Unknown.
etodolac
etodolac and anamu both increase anticoagulation. Minor/Significance Unknown.
fennel
anamu and fennel both increase anticoagulation. Minor/Significance Unknown.
fenoprofen
fenoprofen and anamu both increase anticoagulation. Minor/Significance Unknown.
feverfew
anamu and feverfew both increase anticoagulation. Minor/Significance Unknown.
flurbiprofen
flurbiprofen and anamu both increase anticoagulation. Minor/Significance Unknown.
forskolin
anamu and forskolin both increase anticoagulation. Minor/Significance Unknown.
garlic
anamu and garlic both increase anticoagulation. Minor/Significance Unknown.
ginger
anamu and ginger both increase anticoagulation. Minor/Significance Unknown.
ginkgo biloba
anamu and ginkgo biloba both increase anticoagulation. Minor/Significance Unknown.
glimepiride
anamu increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
glipizide
anamu increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
glyburide
anamu increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
horse chestnut seed
anamu and horse chestnut seed both increase anticoagulation. Minor/Significance Unknown.
ibuprofen
ibuprofen and anamu both increase anticoagulation. Minor/Significance Unknown.
ibuprofen IV
ibuprofen IV and anamu both increase anticoagulation. Minor/Significance Unknown.
indomethacin
indomethacin and anamu both increase anticoagulation. Minor/Significance Unknown.
insulin aspart
anamu increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
insulin detemir
anamu increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
insulin glargine
anamu increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
insulin glulisine
anamu increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
insulin lispro
anamu increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
insulin NPH
anamu increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
insulin regular human
anamu increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
ketoprofen
ketoprofen and anamu both increase anticoagulation. Minor/Significance Unknown.
ketorolac
ketorolac and anamu both increase anticoagulation. Minor/Significance Unknown.
ketorolac intranasal
ketorolac intranasal and anamu both increase anticoagulation. Minor/Significance Unknown.
lornoxicam
lornoxicam and anamu both increase anticoagulation. Minor/Significance Unknown.
meclofenamate
meclofenamate and anamu both increase anticoagulation. Minor/Significance Unknown.
mefenamic acid
mefenamic acid and anamu both increase anticoagulation. Minor/Significance Unknown.
meloxicam
meloxicam and anamu both increase anticoagulation. Minor/Significance Unknown.
metformin
anamu increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
miglitol
anamu increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
mistletoe
anamu increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
nabumetone
nabumetone and anamu both increase anticoagulation. Minor/Significance Unknown.
naproxen
naproxen and anamu both increase anticoagulation. Minor/Significance Unknown.
nateglinide
anamu increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
nettle
anamu increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
oxaprozin
oxaprozin and anamu both increase anticoagulation. Minor/Significance Unknown.
panax ginseng
anamu and panax ginseng both increase anticoagulation. Minor/Significance Unknown.
parecoxib
parecoxib and anamu both increase anticoagulation. Minor/Significance Unknown.
pau d'arco
anamu and pau d'arco both increase anticoagulation. Minor/Significance Unknown.
phytoestrogens
anamu and phytoestrogens both increase anticoagulation. Minor/Significance Unknown.
pioglitazone
anamu increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
piroxicam
piroxicam and anamu both increase anticoagulation. Minor/Significance Unknown.
reishi
anamu and reishi both increase anticoagulation. Minor/Significance Unknown.
repaglinide
anamu increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
rosiglitazone
anamu increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
salicylates (non-asa)
salicylates (non-asa) and anamu both increase anticoagulation. Minor/Significance Unknown.
salsalate
salsalate and anamu both increase anticoagulation. Minor/Significance Unknown.
saxagliptin
anamu increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
Siberian ginseng
anamu and Siberian ginseng both increase anticoagulation. Minor/Significance Unknown.
sitagliptin
anamu increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
sulfasalazine
sulfasalazine and anamu both increase anticoagulation. Minor/Significance Unknown.
sulindac
sulindac and anamu both increase anticoagulation. Minor/Significance Unknown.
tolazamide
anamu increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
tolbutamide
anamu increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
tolfenamic acid
tolfenamic acid and anamu both increase anticoagulation. Minor/Significance Unknown.
tolmetin
tolmetin and anamu both increase anticoagulation. Minor/Significance Unknown.
vildagliptin
anamu increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.

acarbose
Minor (1)anamu increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
aceclofenac
Minor (1)aceclofenac and anamu both increase anticoagulation. Minor/Significance Unknown.
acemetacin
Minor (1)acemetacin and anamu both increase anticoagulation. Minor/Significance Unknown.
agrimony
Minor (1)agrimony and anamu both increase anticoagulation. Minor/Significance Unknown.
alfalfa
Minor (1)alfalfa and anamu both increase anticoagulation. Minor/Significance Unknown.
American ginseng
Minor (1)American ginseng and anamu both increase anticoagulation. Minor/Significance Unknown.
antithrombin alfa
Monitor Closely (1)antithrombin alfa and anamu both increase anticoagulation. Use Caution/Monitor.
antithrombin III
Monitor Closely (1)antithrombin III and anamu both increase anticoagulation. Use Caution/Monitor.
argatroban
Monitor Closely (1)argatroban and anamu both increase anticoagulation. Use Caution/Monitor.
aspirin
Minor (1)aspirin and anamu both increase anticoagulation. Minor/Significance Unknown.
aspirin rectal
Minor (1)aspirin rectal and anamu both increase anticoagulation. Minor/Significance Unknown.
aspirin/citric acid/sodium bicarbonate
Minor (1)aspirin/citric acid/sodium bicarbonate and anamu both increase anticoagulation. Minor/Significance Unknown.
bemiparin
Monitor Closely (1)bemiparin and anamu both increase anticoagulation. Use Caution/Monitor.
bivalirudin
Monitor Closely (1)bivalirudin and anamu both increase anticoagulation. Use Caution/Monitor.
celecoxib
Minor (1)celecoxib and anamu both increase anticoagulation. Minor/Significance Unknown.
chlorpropamide
Minor (1)anamu increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
choline magnesium trisalicylate
Minor (1)choline magnesium trisalicylate and anamu both increase anticoagulation. Minor/Significance Unknown.
cinnamon
Minor (1)anamu and cinnamon both increase anticoagulation. Minor/Significance Unknown.
cordyceps
Minor (1)anamu and cordyceps both increase anticoagulation. Minor/Significance Unknown.
dabigatran
Monitor Closely (1)dabigatran and anamu both increase anticoagulation. Use Caution/Monitor.
dalteparin
Monitor Closely (1)dalteparin and anamu both increase anticoagulation. Use Caution/Monitor.
danshen
Minor (1)anamu and danshen both increase anticoagulation. Minor/Significance Unknown.
devil's claw
Minor (1)anamu and devil's claw both increase anticoagulation. Minor/Significance Unknown.
diclofenac
Minor (1)diclofenac and anamu both increase anticoagulation. Minor/Significance Unknown.
diflunisal
Minor (1)diflunisal and anamu both increase anticoagulation. Minor/Significance Unknown.
dong quai
Minor (1)anamu and dong quai both increase anticoagulation. Minor/Significance Unknown.
enoxaparin
Monitor Closely (1)enoxaparin and anamu both increase anticoagulation. Use Caution/Monitor.
epoprostenol
Minor (1)anamu and epoprostenol both increase anticoagulation. Minor/Significance Unknown.
etodolac
Minor (1)etodolac and anamu both increase anticoagulation. Minor/Significance Unknown.
fennel
Minor (1)anamu and fennel both increase anticoagulation. Minor/Significance Unknown.
fenoprofen
Minor (1)fenoprofen and anamu both increase anticoagulation. Minor/Significance Unknown.
feverfew
Minor (1)anamu and feverfew both increase anticoagulation. Minor/Significance Unknown.
flurbiprofen
Minor (1)flurbiprofen and anamu both increase anticoagulation. Minor/Significance Unknown.
fondaparinux
Monitor Closely (1)fondaparinux and anamu both increase anticoagulation. Use Caution/Monitor.
forskolin
Minor (1)anamu and forskolin both increase anticoagulation. Minor/Significance Unknown.
garlic
Minor (1)anamu and garlic both increase anticoagulation. Minor/Significance Unknown.
ginger
Minor (1)anamu and ginger both increase anticoagulation. Minor/Significance Unknown.
ginkgo biloba
Minor (1)anamu and ginkgo biloba both increase anticoagulation. Minor/Significance Unknown.
glimepiride
Minor (1)anamu increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
glipizide
Minor (1)anamu increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
glyburide
Minor (1)anamu increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
heparin
Monitor Closely (1)heparin and anamu both increase anticoagulation. Use Caution/Monitor.
horse chestnut seed
Minor (1)anamu and horse chestnut seed both increase anticoagulation. Minor/Significance Unknown.
ibuprofen
Minor (1)ibuprofen and anamu both increase anticoagulation. Minor/Significance Unknown.
ibuprofen IV
Minor (1)ibuprofen IV and anamu both increase anticoagulation. Minor/Significance Unknown.
indomethacin
Minor (1)indomethacin and anamu both increase anticoagulation. Minor/Significance Unknown.
insulin aspart
Minor (1)anamu increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
insulin detemir
Minor (1)anamu increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
insulin glargine
Minor (1)anamu increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
insulin glulisine
Minor (1)anamu increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
insulin lispro
Minor (1)anamu increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
insulin NPH
Minor (1)anamu increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
insulin regular human
Minor (1)anamu increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
ketoprofen
Minor (1)ketoprofen and anamu both increase anticoagulation. Minor/Significance Unknown.
ketorolac
Minor (1)ketorolac and anamu both increase anticoagulation. Minor/Significance Unknown.
ketorolac intranasal
Minor (1)ketorolac intranasal and anamu both increase anticoagulation. Minor/Significance Unknown.
lornoxicam
Minor (1)lornoxicam and anamu both increase anticoagulation. Minor/Significance Unknown.
meclofenamate
Minor (1)meclofenamate and anamu both increase anticoagulation. Minor/Significance Unknown.
mefenamic acid
Minor (1)mefenamic acid and anamu both increase anticoagulation. Minor/Significance Unknown.
meloxicam
Minor (1)meloxicam and anamu both increase anticoagulation. Minor/Significance Unknown.
metformin
Minor (1)anamu increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
miglitol
Minor (1)anamu increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
mistletoe
Minor (1)anamu increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
nabumetone
Minor (1)nabumetone and anamu both increase anticoagulation. Minor/Significance Unknown.
naproxen
Minor (1)naproxen and anamu both increase anticoagulation. Minor/Significance Unknown.
nateglinide
Minor (1)anamu increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
nettle
Minor (1)anamu increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
oxaprozin
Minor (1)oxaprozin and anamu both increase anticoagulation. Minor/Significance Unknown.
panax ginseng
Minor (1)anamu and panax ginseng both increase anticoagulation. Minor/Significance Unknown.
parecoxib
Minor (1)parecoxib and anamu both increase anticoagulation. Minor/Significance Unknown.
pau d'arco
Minor (1)anamu and pau d'arco both increase anticoagulation. Minor/Significance Unknown.
phenindione
Monitor Closely (1)phenindione and anamu both increase anticoagulation. Use Caution/Monitor.
phytoestrogens
Minor (1)anamu and phytoestrogens both increase anticoagulation. Minor/Significance Unknown.
pioglitazone
Minor (1)anamu increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
piroxicam
Minor (1)piroxicam and anamu both increase anticoagulation. Minor/Significance Unknown.
protamine
Monitor Closely (1)protamine and anamu both increase anticoagulation. Use Caution/Monitor.
reishi
Minor (1)anamu and reishi both increase anticoagulation. Minor/Significance Unknown.
repaglinide
Minor (1)anamu increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
reteplase
Monitor Closely (1)reteplase and anamu both increase anticoagulation. Use Caution/Monitor.
rosiglitazone
Minor (1)anamu increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
salicylates (non-asa)
Minor (1)salicylates (non-asa) and anamu both increase anticoagulation. Minor/Significance Unknown.
salsalate
Minor (1)salsalate and anamu both increase anticoagulation. Minor/Significance Unknown.
saxagliptin
Minor (1)anamu increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
Siberian ginseng
Minor (1)anamu and Siberian ginseng both increase anticoagulation. Minor/Significance Unknown.
sitagliptin
Minor (1)anamu increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
sulfasalazine
Minor (1)sulfasalazine and anamu both increase anticoagulation. Minor/Significance Unknown.
sulindac
Minor (1)sulindac and anamu both increase anticoagulation. Minor/Significance Unknown.
tenecteplase
Monitor Closely (1)tenecteplase and anamu both increase anticoagulation. Use Caution/Monitor.
tolazamide
Minor (1)anamu increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
tolbutamide
Minor (1)anamu increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.
tolfenamic acid
Minor (1)tolfenamic acid and anamu both increase anticoagulation. Minor/Significance Unknown.
tolmetin
Minor (1)tolmetin and anamu both increase anticoagulation. Minor/Significance Unknown.
vildagliptin
Minor (1)anamu increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction.

Frequency Not Defined

May cause hypoglycemia

Contraindications

Pregnancy

Cautions

Bleeding diathesis, concomitant anticoagulants

DM, hypoglycemia

Pregnancy & Lactation

Pregnancy Category: do not use

Lactation: N/A

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Pharmacology

Metabolism: N/A

Excretion: N/A

Mechanism of Action

Immunostimulatory and anticancerous; contains several putative antineoplastic chemicals (eg, dibenzyl trisulfide) but precise mechanism not known

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

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