Passion Flower (Herb/Suppl)

Brand and Other Names:apricot vine, corona de cristo, more...Fleischfarbige, fleur de la passion, flor de passion, maypop, passiflora incarnata, passion vine, purple passion flower, water lemon, wild passion flower
  • Print

Suggested Dosing

General Dosing Guidlines

Dried

0.25-2 g PO TID

Tea

1 cup PO BID-TID and 30 min before bedtime; 0.25-2 g/150 ml water

Liquid Extract

0.5-1 ml PO TID; 1:1 in 25% alcohol

Tincture

0.5-2 ml PO TID; 1:8 in 45% alcohol

Anxiety Disorder

Liquid extract: 45 gtt PO daily

Opiate Withdrawal

Liquid extract: 60 gtt PO daily

Next:

Suggested Uses

ADHD, cardiac rhythm abnormalities, generalized anxiety disorder, GI upset, hemorrhoids (topical), insomnia, nervousness/excitability, neuralgias, opiate withdrawal symptoms, pain

Efficacy

Possibly effective for nervous restlessness, anxiety, opiate withdrawal when used in combo with clonidine

Previous
Next:

Interactions

Interaction Checker

and Passion Flower

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            All Interactions Sort By:
             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (25)

                • amobarbital

                  passion flower increases effects of amobarbital by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • azelastine

                  passion flower increases effects of azelastine by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • brompheniramine

                  passion flower increases effects of brompheniramine by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • butabarbital

                  passion flower increases effects of butabarbital by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • butalbital

                  passion flower increases effects of butalbital by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • carbinoxamine

                  passion flower increases effects of carbinoxamine by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • chloral hydrate

                  passion flower increases effects of chloral hydrate by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • chlorpheniramine

                  passion flower increases effects of chlorpheniramine by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • cinnarizine

                  passion flower increases effects of cinnarizine by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • clemastine

                  passion flower increases effects of clemastine by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • cyclizine

                  passion flower increases effects of cyclizine by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • cyproheptadine

                  passion flower increases effects of cyproheptadine by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • dexchlorpheniramine

                  passion flower increases effects of dexchlorpheniramine by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • dexmedetomidine

                  passion flower increases effects of dexmedetomidine by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • dimenhydrinate

                  passion flower increases effects of dimenhydrinate by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • diphenhydramine

                  passion flower increases effects of diphenhydramine by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • doxylamine

                  passion flower increases effects of doxylamine by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • hydroxyzine

                  passion flower increases effects of hydroxyzine by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • pentobarbital

                  passion flower increases effects of pentobarbital by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • phenobarbital

                  passion flower increases effects of phenobarbital by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • primidone

                  passion flower increases effects of primidone by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • promethazine

                  passion flower increases effects of promethazine by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • secobarbital

                  passion flower increases effects of secobarbital by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • triclofos

                  passion flower increases effects of triclofos by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                • triprolidine

                  passion flower increases effects of triprolidine by pharmacodynamic synergism. Use Caution/Monitor. May enhance CNS depression.

                Minor (0)

                  Previous
                  Next:

                  Adverse Effects

                  Frequency Not Defined

                  Altered consciousness

                  Ataxia

                  Confusion

                  Dizziness

                  Drowsiness

                  Liver toxicity

                  Nausea/vomiting

                  Pancreas toxicity

                  Prolonged QT interval

                  Vasculitis

                  Ventricular tachycardia

                  Previous
                  Next:

                  Warnings

                  Contraindications

                  None reported

                  Cautions

                  Concurrent sedative agents

                  Previous
                  Next:

                  Pregnancy & Lactation

                  Pregnancy Category: unsafe

                  Lactation: avoid use

                  Pregnancy Categories

                  A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                  B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                  C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                  D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                  X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                  NA: Information not available.

                  Previous
                  Next:

                  Pharmacology

                  Metabolism: N/A

                  Excretion: N/A

                  Mechanism of Action

                  Apigenin: benzodiazepine receptor agonist

                  May have some MAOI activity

                  Previous
                  Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.