Suggested Dosing
2 caps PO TID
1 cap contains
450 mg Withania somnifera (withania, ashwagandha)
100 mg Boswellia serrata (boswellia, Indian frankincense)
50 mg Curcuma longa (turmeric)
50 mg Zinc complex
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Suggested Uses
Osteoarthritis
Efficacy
Significant decrease pain and disability scores, without radiographic changes
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Adverse Effects
Frequency Not Defined
Nausea
Abdominal pain
Dermatitis
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Warnings
Contraindications
Hypersensitivity
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Pregnancy & Lactation
Pregnancy Category: N/A
Lactation: N/A
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Previous
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Pharmacology
Mechanism of Action
Anti-inflammatory within
- Boswellic acids (in boswellia)
- Curcumin (in turmeric)
- Withanolides (in withania)
Immunosuppr. within
- Withaferin-A
- Withanolide-D (in withania)
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
