Articulin (Herb/Suppl)

Brand and Other Names:articulin F

Suggested Dosing

2 caps PO TID

1 cap contains

450 mg Withania somnifera (withania, ashwagandha)

100 mg Boswellia serrata (boswellia, Indian frankincense)

50 mg Curcuma longa (turmeric)

50 mg Zinc complex

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Suggested Uses

Osteoarthritis

Efficacy

Significant decrease pain and disability scores, without radiographic changes

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Adverse Effects

Frequency Not Defined

Nausea

Abdominal pain

Dermatitis

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Warnings

Contraindications

Hypersensitivity

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Pregnancy & Lactation

Pregnancy Category: N/A

Lactation: N/A

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

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Pharmacology

Mechanism of Action

Anti-inflammatory within

  • Boswellic acids (in boswellia)
  • Curcumin (in turmeric)
  • Withanolides (in withania)

Immunosuppr. within

  • Withaferin-A
  • Withanolide-D (in withania)
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.