Pleurisy Root (Herb/Suppl)

Brand and Other Names:asclepsias tuberosa, butterfly weed, more...Canada Root, flux root, orange milkweed, swallowwort, tuber root, white root, wind root
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Suggested Dosing

Tincture: 1-4 mL PO TID in water

Otherwise follow Mfr's instructions

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Suggested Uses

Respiratory problems, eg cough, cold, bronchitis

Uterine d/o, rheumatism

Efficacy: not proven

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Interactions

Interaction Checker

and Pleurisy Root

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            All Interactions Sort By:
             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (0)

                  Minor (35)

                  • amitriptyline

                    pleurisy root decreases effects of amitriptyline by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • amoxapine

                    pleurisy root decreases effects of amoxapine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • bazedoxifene/conjugated estrogens

                    pleurisy root decreases effects of bazedoxifene/conjugated estrogens by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • clomipramine

                    pleurisy root decreases effects of clomipramine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • conjugated estrogens

                    pleurisy root decreases effects of conjugated estrogens by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • conjugated estrogens, vaginal

                    pleurisy root decreases effects of conjugated estrogens, vaginal by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • desipramine

                    pleurisy root decreases effects of desipramine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • digoxin

                    pleurisy root, digoxin. Either increases effects of the other by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction, due to cardenolide glycoside content of pleurisy root.

                  • dosulepin

                    pleurisy root decreases effects of dosulepin by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • doxepin

                    pleurisy root decreases effects of doxepin by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • duloxetine

                    pleurisy root decreases effects of duloxetine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • escitalopram

                    pleurisy root decreases effects of escitalopram by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • estradiol

                    pleurisy root decreases effects of estradiol by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • estrogens conjugated synthetic

                    pleurisy root decreases effects of estrogens conjugated synthetic by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • estrogens esterified

                    pleurisy root decreases effects of estrogens esterified by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • estropipate

                    pleurisy root decreases effects of estropipate by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • fluoxetine

                    pleurisy root decreases effects of fluoxetine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • imipramine

                    pleurisy root decreases effects of imipramine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • isocarboxazid

                    pleurisy root decreases effects of isocarboxazid by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • linezolid

                    pleurisy root decreases effects of linezolid by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • lofepramine

                    pleurisy root decreases effects of lofepramine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • maprotiline

                    pleurisy root decreases effects of maprotiline by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • mestranol

                    pleurisy root decreases effects of mestranol by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • milnacipran

                    pleurisy root decreases effects of milnacipran by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • nefazodone

                    pleurisy root decreases effects of nefazodone by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • nortriptyline

                    pleurisy root decreases effects of nortriptyline by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • paroxetine

                    pleurisy root decreases effects of paroxetine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • phenelzine

                    pleurisy root decreases effects of phenelzine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • procarbazine

                    pleurisy root decreases effects of procarbazine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • protriptyline

                    pleurisy root decreases effects of protriptyline by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • sertraline

                    pleurisy root decreases effects of sertraline by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • tranylcypromine

                    pleurisy root decreases effects of tranylcypromine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • trazodone

                    pleurisy root decreases effects of trazodone by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • trimipramine

                    pleurisy root decreases effects of trimipramine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • venlafaxine

                    pleurisy root decreases effects of venlafaxine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

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                  Adverse Effects

                  Nausea, vomiting, diarrhea, arrythmia

                  Overdose can lead to death d/t respiratory paralysis or heart failure

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                  Warnings

                  Contraindications

                  Pregnancy

                  History of heart disease

                  Hormone dependent neoplasia

                  Cautions

                  Large amounts ingested can be toxic, even fatal

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                  Pregnancy & Lactation

                  Pregnancy Category: contraindicated

                  Lactation: contraindicated

                  Pregnancy Categories

                  A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                  B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                  C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                  D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                  X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                  NA: Information not available.

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                  Pharmacology

                  Metabolism: N/A

                  Excretion: N/A

                  Mechanism of Action

                  May have antiinflammatory properties that relieves respiratory problems & rheumatism

                  May have actions similar to estrogen that palliates uterine problems

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                  Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.