Indication-specific dosing for asclepsias tuberosa, butterfly weed, Canada Root pleurisy root in combination, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.

Sections

Sections Pleurisy Root
Suggested Dosing
Suggested Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology

Suggested Dosing

Tincture: 1-4 mL PO TID in water

Otherwise follow Mfr's instructions

Suggested Uses

Respiratory problems, eg cough, cold, bronchitis

Uterine d/o, rheumatism

Efficacy: not proven

Interaction Checker

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Interactions Found

Contraindicated

Serious - Use Alternative

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Contraindicated (0)

Serious - Use Alternative (0)

Monitor Closely (0)

Minor (35)

amitriptyline
pleurisy root decreases effects of amitriptyline by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
amoxapine
pleurisy root decreases effects of amoxapine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
bazedoxifene/conjugated estrogens
pleurisy root decreases effects of bazedoxifene/conjugated estrogens by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
clomipramine
pleurisy root decreases effects of clomipramine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
conjugated estrogens
pleurisy root decreases effects of conjugated estrogens by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
conjugated estrogens, vaginal
pleurisy root decreases effects of conjugated estrogens, vaginal by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
desipramine
pleurisy root decreases effects of desipramine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
digoxin
pleurisy root, digoxin. Either increases effects of the other by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction, due to cardenolide glycoside content of pleurisy root.
dosulepin
pleurisy root decreases effects of dosulepin by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
doxepin
pleurisy root decreases effects of doxepin by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
duloxetine
pleurisy root decreases effects of duloxetine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
escitalopram
pleurisy root decreases effects of escitalopram by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
estradiol
pleurisy root decreases effects of estradiol by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
estrogens conjugated synthetic
pleurisy root decreases effects of estrogens conjugated synthetic by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
estrogens esterified
pleurisy root decreases effects of estrogens esterified by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
estropipate
pleurisy root decreases effects of estropipate by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
fluoxetine
pleurisy root decreases effects of fluoxetine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
imipramine
pleurisy root decreases effects of imipramine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
isocarboxazid
pleurisy root decreases effects of isocarboxazid by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
linezolid
pleurisy root decreases effects of linezolid by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
lofepramine
pleurisy root decreases effects of lofepramine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
maprotiline
pleurisy root decreases effects of maprotiline by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
mestranol
pleurisy root decreases effects of mestranol by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
milnacipran
pleurisy root decreases effects of milnacipran by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
nefazodone
pleurisy root decreases effects of nefazodone by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
nortriptyline
pleurisy root decreases effects of nortriptyline by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
paroxetine
pleurisy root decreases effects of paroxetine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
phenelzine
pleurisy root decreases effects of phenelzine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
procarbazine
pleurisy root decreases effects of procarbazine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
protriptyline
pleurisy root decreases effects of protriptyline by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
sertraline
pleurisy root decreases effects of sertraline by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
tranylcypromine
pleurisy root decreases effects of tranylcypromine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
trazodone
pleurisy root decreases effects of trazodone by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
trimipramine
pleurisy root decreases effects of trimipramine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
venlafaxine
pleurisy root decreases effects of venlafaxine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

amitriptyline
Minor (1)pleurisy root decreases effects of amitriptyline by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
amoxapine
Minor (1)pleurisy root decreases effects of amoxapine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
bazedoxifene/conjugated estrogens
Minor (1)pleurisy root decreases effects of bazedoxifene/conjugated estrogens by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
clomipramine
Minor (1)pleurisy root decreases effects of clomipramine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
conjugated estrogens
Minor (1)pleurisy root decreases effects of conjugated estrogens by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
conjugated estrogens, vaginal
Minor (1)pleurisy root decreases effects of conjugated estrogens, vaginal by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
desipramine
Minor (1)pleurisy root decreases effects of desipramine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
digoxin
Minor (1)pleurisy root, digoxin. Either increases effects of the other by pharmacodynamic synergism. Minor/Significance Unknown. Theoretical interaction, due to cardenolide glycoside content of pleurisy root.
dosulepin
Minor (1)pleurisy root decreases effects of dosulepin by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
doxepin
Minor (1)pleurisy root decreases effects of doxepin by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
duloxetine
Minor (1)pleurisy root decreases effects of duloxetine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
escitalopram
Minor (1)pleurisy root decreases effects of escitalopram by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
estradiol
Minor (1)pleurisy root decreases effects of estradiol by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
estrogens conjugated synthetic
Minor (1)pleurisy root decreases effects of estrogens conjugated synthetic by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
estrogens esterified
Minor (1)pleurisy root decreases effects of estrogens esterified by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
estropipate
Minor (1)pleurisy root decreases effects of estropipate by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
fluoxetine
Minor (1)pleurisy root decreases effects of fluoxetine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
imipramine
Minor (1)pleurisy root decreases effects of imipramine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
isocarboxazid
Minor (1)pleurisy root decreases effects of isocarboxazid by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
linezolid
Minor (1)pleurisy root decreases effects of linezolid by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
lofepramine
Minor (1)pleurisy root decreases effects of lofepramine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
maprotiline
Minor (1)pleurisy root decreases effects of maprotiline by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
mestranol
Minor (1)pleurisy root decreases effects of mestranol by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
milnacipran
Minor (1)pleurisy root decreases effects of milnacipran by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
nefazodone
Minor (1)pleurisy root decreases effects of nefazodone by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
nortriptyline
Minor (1)pleurisy root decreases effects of nortriptyline by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
paroxetine
Minor (1)pleurisy root decreases effects of paroxetine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
phenelzine
Minor (1)pleurisy root decreases effects of phenelzine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
procarbazine
Minor (1)pleurisy root decreases effects of procarbazine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
protriptyline
Minor (1)pleurisy root decreases effects of protriptyline by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
sertraline
Minor (1)pleurisy root decreases effects of sertraline by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
tranylcypromine
Minor (1)pleurisy root decreases effects of tranylcypromine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
trazodone
Minor (1)pleurisy root decreases effects of trazodone by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
trimipramine
Minor (1)pleurisy root decreases effects of trimipramine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.
venlafaxine
Minor (1)pleurisy root decreases effects of venlafaxine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

Adverse Effects

Nausea, vomiting, diarrhea, arrythmia

Overdose can lead to death d/t respiratory paralysis or heart failure

Contraindications

Pregnancy

History of heart disease

Hormone dependent neoplasia

Cautions

Large amounts ingested can be toxic, even fatal

Pregnancy & Lactation

Pregnancy Category: contraindicated

Lactation: contraindicated

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Pharmacology

Metabolism: N/A

Excretion: N/A

Mechanism of Action

May have antiinflammatory properties that relieves respiratory problems & rheumatism

May have actions similar to estrogen that palliates uterine problems

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

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Sections Pleurisy Root
Suggested Dosing
Suggested Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology

Pleurisy Root (Herb/Suppl)