Indication-specific dosing for Asian Ginseng, Chinese Ginseng, ginseng radix panax ginseng in combination, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.

Sections

Sections Panax Ginseng
Suggested Dosing
Suggested Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology

Suggested Dosing

Cut or Powdered Root

0.6-3 g PO qDay-TID

Brewed Root Tea

3 g PO qDay-TID

Erectile Dysfunction

900 mg PO TID

Topically cream applied 1 hour prior to intercouse and washed off before intercourse has been used

Diabetes

200 mg PO qDay

Other Information

100-300 mg extract TID for 3-4 weeks

Extract standardized to 7% ginsenosides

Suggested Uses

Adaptogen: adapt to internal/external stressors, fight fatigue, increase stamina

Anxiety, athletic/physical stamina enhancement, cognitive function, enhancement, depression, fertility (male), headaches, immunostimulant, menopausal hot-flashes, impotence

Efficacy

Possibly effective in cognitive function, diabetes, erectile dysfunction and premature ejaculation

Possibly ineffective for athletic performance, menopausal symptoms and quality of life

Insufficient reliable evidence to rate breast cancer, bronchitis, cancer, common cold, congestive heart failure and influenza

Interaction Checker

Enter a drug name and Panax Ginseng

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Contraindicated

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Minor

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Contraindicated (0)

Serious - Use Alternative (0)

Monitor Closely (68)

aceclofenac
aceclofenac and panax ginseng both increase anticoagulation. Use Caution/Monitor.
acemetacin
acemetacin and panax ginseng both increase anticoagulation. Use Caution/Monitor.
agrimony
agrimony and panax ginseng both increase anticoagulation. Use Caution/Monitor.
alfalfa
alfalfa and panax ginseng both increase anticoagulation. Use Caution/Monitor.
alteplase
alteplase and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
American ginseng
American ginseng and panax ginseng both increase anticoagulation. Use Caution/Monitor.
antithrombin alfa
antithrombin alfa and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
antithrombin III
antithrombin III and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
argatroban
argatroban and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
aspirin
aspirin and panax ginseng both increase anticoagulation. Use Caution/Monitor.
aspirin rectal
aspirin rectal and panax ginseng both increase anticoagulation. Use Caution/Monitor.
aspirin/citric acid/sodium bicarbonate
aspirin/citric acid/sodium bicarbonate and panax ginseng both increase anticoagulation. Use Caution/Monitor.
bemiparin
bemiparin and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
bivalirudin
bivalirudin and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
celecoxib
celecoxib and panax ginseng both increase anticoagulation. Use Caution/Monitor.
cinnamon
cinnamon and panax ginseng both increase anticoagulation. Use Caution/Monitor.
cordyceps
cordyceps and panax ginseng both increase anticoagulation. Use Caution/Monitor.
dabigatran
dabigatran and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
dalteparin
dalteparin and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
diclofenac
diclofenac and panax ginseng both increase anticoagulation. Use Caution/Monitor.
diflunisal
diflunisal and panax ginseng both increase anticoagulation. Use Caution/Monitor.
dong quai
dong quai and panax ginseng both increase anticoagulation. Use Caution/Monitor.
enoxaparin
enoxaparin and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
epoprostenol
epoprostenol and panax ginseng both increase anticoagulation. Use Caution/Monitor.
etodolac
etodolac and panax ginseng both increase anticoagulation. Use Caution/Monitor.
fennel
fennel and panax ginseng both increase anticoagulation. Use Caution/Monitor.
fenoprofen
fenoprofen and panax ginseng both increase anticoagulation. Use Caution/Monitor.
feverfew
feverfew and panax ginseng both increase anticoagulation. Use Caution/Monitor.
flurbiprofen
flurbiprofen and panax ginseng both increase anticoagulation. Use Caution/Monitor.
fondaparinux
fondaparinux and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
forskolin
forskolin and panax ginseng both increase anticoagulation. Use Caution/Monitor.
garlic
garlic and panax ginseng both increase anticoagulation. Use Caution/Monitor.
ginger
ginger and panax ginseng both increase anticoagulation. Use Caution/Monitor.
ginkgo biloba
ginkgo biloba and panax ginseng both increase anticoagulation. Use Caution/Monitor.
heparin
heparin and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
horse chestnut seed
horse chestnut seed and panax ginseng both increase anticoagulation. Use Caution/Monitor.
ibuprofen
ibuprofen and panax ginseng both increase anticoagulation. Use Caution/Monitor.
ibuprofen IV
ibuprofen IV and panax ginseng both increase anticoagulation. Use Caution/Monitor.
indomethacin
indomethacin and panax ginseng both increase anticoagulation. Use Caution/Monitor.
ketoprofen
ketoprofen and panax ginseng both increase anticoagulation. Use Caution/Monitor.
ketorolac
ketorolac and panax ginseng both increase anticoagulation. Use Caution/Monitor.
ketorolac intranasal
ketorolac intranasal and panax ginseng both increase anticoagulation. Use Caution/Monitor.
lornoxicam
lornoxicam and panax ginseng both increase anticoagulation. Use Caution/Monitor.
meclofenamate
meclofenamate and panax ginseng both increase anticoagulation. Use Caution/Monitor.
mefenamic acid
mefenamic acid and panax ginseng both increase anticoagulation. Use Caution/Monitor.
meloxicam
meloxicam and panax ginseng both increase anticoagulation. Use Caution/Monitor.
mistletoe
panax ginseng increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.
nabumetone
nabumetone and panax ginseng both increase anticoagulation. Use Caution/Monitor.
naproxen
naproxen and panax ginseng both increase anticoagulation. Use Caution/Monitor.
nettle
panax ginseng increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.
oxaprozin
oxaprozin and panax ginseng both increase anticoagulation. Use Caution/Monitor.
parecoxib
parecoxib and panax ginseng both increase anticoagulation. Use Caution/Monitor.
pau d'arco
panax ginseng and pau d'arco both increase anticoagulation. Use Caution/Monitor.
phenindione
phenindione and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
phytoestrogens
panax ginseng and phytoestrogens both increase anticoagulation. Use Caution/Monitor.
piroxicam
piroxicam and panax ginseng both increase anticoagulation. Use Caution/Monitor.
protamine
protamine and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
reishi
panax ginseng and reishi both increase anticoagulation. Use Caution/Monitor.
reteplase
reteplase and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
salicylates (non-asa)
salicylates (non-asa) and panax ginseng both increase anticoagulation. Use Caution/Monitor.
salsalate
salsalate and panax ginseng both increase anticoagulation. Use Caution/Monitor.
Siberian ginseng
panax ginseng and Siberian ginseng both increase anticoagulation. Use Caution/Monitor.
sulfasalazine
sulfasalazine and panax ginseng both increase anticoagulation. Use Caution/Monitor.
sulindac
sulindac and panax ginseng both increase anticoagulation. Use Caution/Monitor.
tenecteplase
tenecteplase and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
tolfenamic acid
tolfenamic acid and panax ginseng both increase anticoagulation. Use Caution/Monitor.
tolmetin
tolmetin and panax ginseng both increase anticoagulation. Use Caution/Monitor.
vitamin K1 (phytonadione)
panax ginseng increases and vitamin K1 (phytonadione) decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

Minor (37)

amitriptyline
panax ginseng increases effects of amitriptyline by pharmacodynamic synergism. Minor/Significance Unknown.
amoxapine
panax ginseng increases effects of amoxapine by pharmacodynamic synergism. Minor/Significance Unknown.
anamu
anamu and panax ginseng both increase anticoagulation. Minor/Significance Unknown.
clomipramine
panax ginseng increases effects of clomipramine by pharmacodynamic synergism. Minor/Significance Unknown.
danshen
danshen and panax ginseng both increase anticoagulation. Minor/Significance Unknown.
desipramine
panax ginseng increases effects of desipramine by pharmacodynamic synergism. Minor/Significance Unknown.
devil's claw
devil's claw and panax ginseng both increase anticoagulation. Minor/Significance Unknown.
dosulepin
panax ginseng increases effects of dosulepin by pharmacodynamic synergism. Minor/Significance Unknown.
doxepin
panax ginseng increases effects of doxepin by pharmacodynamic synergism. Minor/Significance Unknown.
duloxetine
panax ginseng increases effects of duloxetine by pharmacodynamic synergism. Minor/Significance Unknown.
escitalopram
panax ginseng increases effects of escitalopram by pharmacodynamic synergism. Minor/Significance Unknown.
fluoxetine
panax ginseng increases effects of fluoxetine by pharmacodynamic synergism. Minor/Significance Unknown.
green tea
green tea, panax ginseng. Other (see comment). Minor/Significance Unknown. Comment: Use caution when combining green tea with herbs that exhibit antiplatelet effects or anticoagulant activity.
imipramine
panax ginseng increases effects of imipramine by pharmacodynamic synergism. Minor/Significance Unknown.
insulin aspart
panax ginseng increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown.
insulin detemir
panax ginseng increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown.
insulin glargine
panax ginseng increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown.
insulin glulisine
panax ginseng increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown.
insulin lispro
panax ginseng increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown.
insulin NPH
panax ginseng increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown.
insulin regular human
panax ginseng increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown.
isocarboxazid
panax ginseng increases effects of isocarboxazid by pharmacodynamic synergism. Minor/Significance Unknown.
linezolid
panax ginseng increases effects of linezolid by pharmacodynamic synergism. Minor/Significance Unknown.
lofepramine
panax ginseng increases effects of lofepramine by pharmacodynamic synergism. Minor/Significance Unknown.
maprotiline
panax ginseng increases effects of maprotiline by pharmacodynamic synergism. Minor/Significance Unknown.
milnacipran
panax ginseng increases effects of milnacipran by pharmacodynamic synergism. Minor/Significance Unknown.
nefazodone
panax ginseng increases effects of nefazodone by pharmacodynamic synergism. Minor/Significance Unknown.
nortriptyline
panax ginseng increases effects of nortriptyline by pharmacodynamic synergism. Minor/Significance Unknown.
paroxetine
panax ginseng increases effects of paroxetine by pharmacodynamic synergism. Minor/Significance Unknown.
phenelzine
panax ginseng increases effects of phenelzine by pharmacodynamic synergism. Minor/Significance Unknown.
procarbazine
panax ginseng increases effects of procarbazine by pharmacodynamic synergism. Minor/Significance Unknown.
protriptyline
panax ginseng increases effects of protriptyline by pharmacodynamic synergism. Minor/Significance Unknown.
sertraline
panax ginseng increases effects of sertraline by pharmacodynamic synergism. Minor/Significance Unknown.
tranylcypromine
panax ginseng increases effects of tranylcypromine by pharmacodynamic synergism. Minor/Significance Unknown.
trazodone
panax ginseng increases effects of trazodone by pharmacodynamic synergism. Minor/Significance Unknown.
trimipramine
panax ginseng increases effects of trimipramine by pharmacodynamic synergism. Minor/Significance Unknown.
venlafaxine
panax ginseng increases effects of venlafaxine by pharmacodynamic synergism. Minor/Significance Unknown.

aceclofenac
Monitor Closely (1)aceclofenac and panax ginseng both increase anticoagulation. Use Caution/Monitor.
acemetacin
Monitor Closely (1)acemetacin and panax ginseng both increase anticoagulation. Use Caution/Monitor.
agrimony
Monitor Closely (1)agrimony and panax ginseng both increase anticoagulation. Use Caution/Monitor.
alfalfa
Monitor Closely (1)alfalfa and panax ginseng both increase anticoagulation. Use Caution/Monitor.
alteplase
Monitor Closely (1)alteplase and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
American ginseng
Monitor Closely (1)American ginseng and panax ginseng both increase anticoagulation. Use Caution/Monitor.
amitriptyline
Minor (1)panax ginseng increases effects of amitriptyline by pharmacodynamic synergism. Minor/Significance Unknown.
amoxapine
Minor (1)panax ginseng increases effects of amoxapine by pharmacodynamic synergism. Minor/Significance Unknown.
anamu
Minor (1)anamu and panax ginseng both increase anticoagulation. Minor/Significance Unknown.
antithrombin alfa
Monitor Closely (1)antithrombin alfa and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
antithrombin III
Monitor Closely (1)antithrombin III and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
argatroban
Monitor Closely (1)argatroban and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
aspirin
Monitor Closely (1)aspirin and panax ginseng both increase anticoagulation. Use Caution/Monitor.
aspirin rectal
Monitor Closely (1)aspirin rectal and panax ginseng both increase anticoagulation. Use Caution/Monitor.
aspirin/citric acid/sodium bicarbonate
Monitor Closely (1)aspirin/citric acid/sodium bicarbonate and panax ginseng both increase anticoagulation. Use Caution/Monitor.
bemiparin
Monitor Closely (1)bemiparin and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
bivalirudin
Monitor Closely (1)bivalirudin and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
celecoxib
Monitor Closely (1)celecoxib and panax ginseng both increase anticoagulation. Use Caution/Monitor.
cinnamon
Monitor Closely (1)cinnamon and panax ginseng both increase anticoagulation. Use Caution/Monitor.
clomipramine
Minor (1)panax ginseng increases effects of clomipramine by pharmacodynamic synergism. Minor/Significance Unknown.
cordyceps
Monitor Closely (1)cordyceps and panax ginseng both increase anticoagulation. Use Caution/Monitor.
dabigatran
Monitor Closely (1)dabigatran and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
dalteparin
Monitor Closely (1)dalteparin and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
danshen
Minor (1)danshen and panax ginseng both increase anticoagulation. Minor/Significance Unknown.
desipramine
Minor (1)panax ginseng increases effects of desipramine by pharmacodynamic synergism. Minor/Significance Unknown.
devil's claw
Minor (1)devil's claw and panax ginseng both increase anticoagulation. Minor/Significance Unknown.
diclofenac
Monitor Closely (1)diclofenac and panax ginseng both increase anticoagulation. Use Caution/Monitor.
diflunisal
Monitor Closely (1)diflunisal and panax ginseng both increase anticoagulation. Use Caution/Monitor.
dong quai
Monitor Closely (1)dong quai and panax ginseng both increase anticoagulation. Use Caution/Monitor.
dosulepin
Minor (1)panax ginseng increases effects of dosulepin by pharmacodynamic synergism. Minor/Significance Unknown.
doxepin
Minor (1)panax ginseng increases effects of doxepin by pharmacodynamic synergism. Minor/Significance Unknown.
duloxetine
Minor (1)panax ginseng increases effects of duloxetine by pharmacodynamic synergism. Minor/Significance Unknown.
enoxaparin
Monitor Closely (1)enoxaparin and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
epoprostenol
Monitor Closely (1)epoprostenol and panax ginseng both increase anticoagulation. Use Caution/Monitor.
escitalopram
Minor (1)panax ginseng increases effects of escitalopram by pharmacodynamic synergism. Minor/Significance Unknown.
etodolac
Monitor Closely (1)etodolac and panax ginseng both increase anticoagulation. Use Caution/Monitor.
fennel
Monitor Closely (1)fennel and panax ginseng both increase anticoagulation. Use Caution/Monitor.
fenoprofen
Monitor Closely (1)fenoprofen and panax ginseng both increase anticoagulation. Use Caution/Monitor.
feverfew
Monitor Closely (1)feverfew and panax ginseng both increase anticoagulation. Use Caution/Monitor.
fluoxetine
Minor (1)panax ginseng increases effects of fluoxetine by pharmacodynamic synergism. Minor/Significance Unknown.
flurbiprofen
Monitor Closely (1)flurbiprofen and panax ginseng both increase anticoagulation. Use Caution/Monitor.
fondaparinux
Monitor Closely (1)fondaparinux and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
forskolin
Monitor Closely (1)forskolin and panax ginseng both increase anticoagulation. Use Caution/Monitor.
garlic
Monitor Closely (1)garlic and panax ginseng both increase anticoagulation. Use Caution/Monitor.
ginger
Monitor Closely (1)ginger and panax ginseng both increase anticoagulation. Use Caution/Monitor.
ginkgo biloba
Monitor Closely (1)ginkgo biloba and panax ginseng both increase anticoagulation. Use Caution/Monitor.
green tea
Minor (1)green tea, panax ginseng. Other (see comment). Minor/Significance Unknown. Comment: Use caution when combining green tea with herbs that exhibit antiplatelet effects or anticoagulant activity.
heparin
Monitor Closely (1)heparin and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
horse chestnut seed
Monitor Closely (1)horse chestnut seed and panax ginseng both increase anticoagulation. Use Caution/Monitor.
ibuprofen
Monitor Closely (1)ibuprofen and panax ginseng both increase anticoagulation. Use Caution/Monitor.
ibuprofen IV
Monitor Closely (1)ibuprofen IV and panax ginseng both increase anticoagulation. Use Caution/Monitor.
imipramine
Minor (1)panax ginseng increases effects of imipramine by pharmacodynamic synergism. Minor/Significance Unknown.
indomethacin
Monitor Closely (1)indomethacin and panax ginseng both increase anticoagulation. Use Caution/Monitor.
insulin aspart
Minor (1)panax ginseng increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown.
insulin detemir
Minor (1)panax ginseng increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown.
insulin glargine
Minor (1)panax ginseng increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown.
insulin glulisine
Minor (1)panax ginseng increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown.
insulin lispro
Minor (1)panax ginseng increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown.
insulin NPH
Minor (1)panax ginseng increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown.
insulin regular human
Minor (1)panax ginseng increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown.
isocarboxazid
Minor (1)panax ginseng increases effects of isocarboxazid by pharmacodynamic synergism. Minor/Significance Unknown.
ketoprofen
Monitor Closely (1)ketoprofen and panax ginseng both increase anticoagulation. Use Caution/Monitor.
ketorolac
Monitor Closely (1)ketorolac and panax ginseng both increase anticoagulation. Use Caution/Monitor.
ketorolac intranasal
Monitor Closely (1)ketorolac intranasal and panax ginseng both increase anticoagulation. Use Caution/Monitor.
linezolid
Minor (1)panax ginseng increases effects of linezolid by pharmacodynamic synergism. Minor/Significance Unknown.
lofepramine
Minor (1)panax ginseng increases effects of lofepramine by pharmacodynamic synergism. Minor/Significance Unknown.
lornoxicam
Monitor Closely (1)lornoxicam and panax ginseng both increase anticoagulation. Use Caution/Monitor.
maprotiline
Minor (1)panax ginseng increases effects of maprotiline by pharmacodynamic synergism. Minor/Significance Unknown.
meclofenamate
Monitor Closely (1)meclofenamate and panax ginseng both increase anticoagulation. Use Caution/Monitor.
mefenamic acid
Monitor Closely (1)mefenamic acid and panax ginseng both increase anticoagulation. Use Caution/Monitor.
meloxicam
Monitor Closely (1)meloxicam and panax ginseng both increase anticoagulation. Use Caution/Monitor.
milnacipran
Minor (1)panax ginseng increases effects of milnacipran by pharmacodynamic synergism. Minor/Significance Unknown.
mistletoe
Monitor Closely (1)panax ginseng increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.
nabumetone
Monitor Closely (1)nabumetone and panax ginseng both increase anticoagulation. Use Caution/Monitor.
naproxen
Monitor Closely (1)naproxen and panax ginseng both increase anticoagulation. Use Caution/Monitor.
nefazodone
Minor (1)panax ginseng increases effects of nefazodone by pharmacodynamic synergism. Minor/Significance Unknown.
nettle
Monitor Closely (1)panax ginseng increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.
nortriptyline
Minor (1)panax ginseng increases effects of nortriptyline by pharmacodynamic synergism. Minor/Significance Unknown.
oxaprozin
Monitor Closely (1)oxaprozin and panax ginseng both increase anticoagulation. Use Caution/Monitor.
parecoxib
Monitor Closely (1)parecoxib and panax ginseng both increase anticoagulation. Use Caution/Monitor.
paroxetine
Minor (1)panax ginseng increases effects of paroxetine by pharmacodynamic synergism. Minor/Significance Unknown.
pau d'arco
Monitor Closely (1)panax ginseng and pau d'arco both increase anticoagulation. Use Caution/Monitor.
phenelzine
Minor (1)panax ginseng increases effects of phenelzine by pharmacodynamic synergism. Minor/Significance Unknown.
phenindione
Monitor Closely (1)phenindione and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
phytoestrogens
Monitor Closely (1)panax ginseng and phytoestrogens both increase anticoagulation. Use Caution/Monitor.
piroxicam
Monitor Closely (1)piroxicam and panax ginseng both increase anticoagulation. Use Caution/Monitor.
procarbazine
Minor (1)panax ginseng increases effects of procarbazine by pharmacodynamic synergism. Minor/Significance Unknown.
protamine
Monitor Closely (1)protamine and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
protriptyline
Minor (1)panax ginseng increases effects of protriptyline by pharmacodynamic synergism. Minor/Significance Unknown.
reishi
Monitor Closely (1)panax ginseng and reishi both increase anticoagulation. Use Caution/Monitor.
reteplase
Monitor Closely (1)reteplase and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
salicylates (non-asa)
Monitor Closely (1)salicylates (non-asa) and panax ginseng both increase anticoagulation. Use Caution/Monitor.
salsalate
Monitor Closely (1)salsalate and panax ginseng both increase anticoagulation. Use Caution/Monitor.
sertraline
Minor (1)panax ginseng increases effects of sertraline by pharmacodynamic synergism. Minor/Significance Unknown.
Siberian ginseng
Monitor Closely (1)panax ginseng and Siberian ginseng both increase anticoagulation. Use Caution/Monitor.
sulfasalazine
Monitor Closely (1)sulfasalazine and panax ginseng both increase anticoagulation. Use Caution/Monitor.
sulindac
Monitor Closely (1)sulindac and panax ginseng both increase anticoagulation. Use Caution/Monitor.
tenecteplase
Monitor Closely (1)tenecteplase and panax ginseng both increase anticoagulation. Modify Therapy/Monitor Closely.
tolfenamic acid
Monitor Closely (1)tolfenamic acid and panax ginseng both increase anticoagulation. Use Caution/Monitor.
tolmetin
Monitor Closely (1)tolmetin and panax ginseng both increase anticoagulation. Use Caution/Monitor.
tranylcypromine
Minor (1)panax ginseng increases effects of tranylcypromine by pharmacodynamic synergism. Minor/Significance Unknown.
trazodone
Minor (1)panax ginseng increases effects of trazodone by pharmacodynamic synergism. Minor/Significance Unknown.
trimipramine
Minor (1)panax ginseng increases effects of trimipramine by pharmacodynamic synergism. Minor/Significance Unknown.
venlafaxine
Minor (1)panax ginseng increases effects of venlafaxine by pharmacodynamic synergism. Minor/Significance Unknown.
vitamin K1 (phytonadione)
Monitor Closely (1)panax ginseng increases and vitamin K1 (phytonadione) decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

Frequency Not Defined

Allergic skin reactions

Amenorrhea

Appetite decreased

Cerebral arteritis

Cholestatic hepatitis

Diarrhea

Edema

Euphoria

Headache

Hyperpyrexia

Hypertension

Hypotension

Insomnia

Mania

Mastalgia

Neonatal death

Palpitations

Pruritis

Rose spots

Stevens-Johnson syndrome

Tachycardia

Vaginal bleeding

Vertigo

Contraindications

Bleeding disorders, breast cancer, endometrial cancer, endometriosis, estrogen-dependent malignancies, diabetes, hormone sensitive conditions, hypertension, hypersensitivity, neonates, organ transplant recipients, ovarian cancer, pregnancy, thromboembolic disorders, uterine fibroids

Cautions

Cardiovascular disease, concurrent CYP2D6 substrates, diabetes mellitus, insomnia, peds, schizophrenia

Pregnancy & Lactation

Pregnancy Category: X

Lactation: N/A

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Mechanism of Action

Ginsenosides have many different effects, and varying concentrations

Some ADRs caused by contaminants

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

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Sections Panax Ginseng
Suggested Dosing
Suggested Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology

Panax Ginseng (Herb/Suppl)