Dosing & Uses
Mucositis
Pending FDA approval for radiotherapy-induced severe oral mucositis (SOM) in patients with head and neck cancer
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Pharmacology
Mechanism of Action
Mimetic of the enzyme superoxide dismutase (SOD) that may potentially be used to reduce oral mucositis and esophagitis associated with radiation therapy and chemoradiotherapy
Upon administration, avasopasem manganese may mimic native SODs and catalyze formation of molecular oxygen and hydrogen peroxide from the burst of superoxide anion present in irradiated tissues upon radiation
This may decrease radiation damage to normal tissues
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Images
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
