Suggested Dosing
Hypercholesterolemia
1200 mg/day PO capsules
1-2 Tbs 1-3 times daily as functional foods (margarine, salad dressing)
Bayer Heart Health Advantage
- 12 years or older: 400 mg PO BID with meals
Benign Prostatic Hyperplasia
60 -130 mg/day PO divided BID/TID of beta-sitosterol
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Suggested Uses
Hypercholesterolemia, Benign prostatic hyperplasia (BPH).
Efficacy
Proven effective in lowering LDL in conjunction with diet & exercise
Improves urinary symptoms with BPH
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Adverse Effects
Frequency Not Defined
Xanthomatosis
Atherosclerosis in patients with sitosterolemia (very rare)
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Warnings
Contraindications
N/A
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Pregnancy & Lactation
Pregnancy Category: N/A
Lactation: N/A
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Previous
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Pharmacology
Metabolism: N/A
Excretion: N/A
Mechanism of Action
Plant-derived sterols; decr cholesterol absorption from small intestine
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
