Dosing & Uses
Dosage Forms & Strengths
gel/topical solution
- 6.3%
- 7.5%
- 10%
- 20%
liquid
- 5%
- 6.3%
- 7.5%
- 10%
- 20%
Bee Stings, Minor Burns, Sunburn, Insect Bites
Apply 5-20% to affected area q6-8hr PRN; remove sting prior to application if a bee sting
Mouth and Gum Irritation
Apply 10-20% solution (or other topical formulation) PRN
Sore Throat/Mouth Pain
1 lozenge dissolved in mouth; repeat q2hr PRN (generally use <2 days)
Apply 1 spray to affected area; spit after 1 min; may repeat up to 4 times
Hemorrhoids
Apply 5-20% externally to affected area q4hr
Dental pain
Use 2.5-20% solution (or other topical formulation) PRN
Boils
Apply 20% to affected area; not to exceed q12hr
Premature Ejaculation
EjectDelay (7.5% gel): Apply small amount to the penis gland 15-20 min before sexual intercourse
It can be applied with or without a condom
Washed off after intercourse
Dosage Forms & Strengths
gel/topical solution
- 6.3%
- 7.5%
- 10%
- 20%
liquid
- 5%
- 6.3%
- 7.5%
- 10%
- 20%
Teething Pain
<4 years
- Safety and efficacy not established
≥4 years
- Apply 7.5-10% to affected gum area; not to exceed q6hr
Bee Stings, Boils, Minor Burns, Sunburn, Insect Bites
<2 years
- Safety and efficacy not established
≥2 years
- Apply 5-20% to affected area q6-8hr PRN; remove sting prior to application if a bee sting
Mouth and Gum Irritation
<2 years: safety and efficacy not established
≥2 years: Apply 10-20% solution (or other topical formulation) PRN
Sore Throat/Mouth Pain
<5 years: Safety and efficacy not established
≥5 years
- Oral lozenge: 1 lozenge dissolved in mouth; repeat q2hr PRN (generally use <2 days)
- Oral spray: Apply 1 spray to affected area; spit after 1 min; may repeat up to 4 times
Hemorrhoids
<12 years: Safety and efficacy not established
≥12 years: Apply 5-20% externally to affected area q4hr
Adverse Effects
Frequency Not Defined
Burning
Contact dermatitis
Edema
Pruritus
Erythema
Rash
Stinging tenderness
Urticaria
Methemoglobenemia
Warnings
Contraindications
Hypersensitivity to benzocaine or other ester-type local anesthetics
Secondary bacterial infection of treated area
Cautions
Not for prolonged use
Risk of methemoglobinemia when used in mouth or throat
Pregnancy & Lactation
Pregnancy Category: C
Lactation: excretion in milk unknown; use with caution
Pregnancy Categories
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Pharmacology
Mechanism of Action
Local anesthetics prevent generation/conduction of nerve impulses by reducing sodium permeability and by increasing action potential threshold
