Dosing & Uses
Epidermolysis Bullosa
Topical gene therapy pending FDA approval
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Pharmacology
Mechanism of Action
Recombinant herpes simplex virus type 1 (HSV-1) vector expressing the COL7A1 gene, which encodes type VII collagen
In recessive dystrophic epidermolysis bullosa, a flawed COL7A1 gene results in loss of type VII collagen, an important structural skin protein
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Images
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
