Dosing & Uses
Topical Antiseptic
Apply to clean wound PRN
Surgical Scrub
Apply solution to wet hands and scrub for 5 min
Endophthalmitis (Orphan)
Orphan designation for treatment of endophthalmitis
Orphan sponsor
- Cumulus Pharmaceutical LLC; 1712 Pioneer Avenue, Suite 1377; Cheyenne, Wyoming 82001
Safety and efficacy in children not established
Interactions
Interaction Checker
No Results
Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor
Adverse Effects
Frequency Not Defined
Hypothyroidism in neonates (<28 days old) after use by mother prior to delivery; use with caution in pregnancy, lactation and children
Severe pain on application
Irritation
Pruritus
Erythema
Rash
Edematous erythema
Acneform eruption
Warnings
Contraindications
Hypersensitivity
Cautions
Toxicity may occur if applied in large quantities or prolonged periods of time
Use caution in patients with burns
Use caution in renal impairment or thyroid disorders
Use with caution in children
Not for application to deep puncture wounds or serious burns
Discontinue if swelling, redness, pain or irritation develop
Do not use for longer than 1 week
Pregnancy & Lactation
Pregnancy Category: B
Lactation: Use caution; enters breast
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Wide spectrum microbicidal; oxidizes cell constituents; iodinates proteins and inactivates them
Pharmacokinetics
Absorption: Systemic absorptoin as iodine
