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      News & Perspective Drugs & Diseases CME & Education Academy Video Decision Point
      Drugs & Diseases

      Shepherd's Purse (Herb/Suppl)

      Brand and Other Names:blindweed, caseweed, more...cocowort, lady's purse, mothers heart, pepper & salt, pickpocket, poor man's parmacettie, St James weed, witches' pouches
      • Print

      Suggested Dosing

      Insufficent reliable evidence on effectiveness

      Oral: 1-4 g PO TID

      Crushed herb: 10-15 g/d PO (may div TID)

      Liquid extract: 5-8 g/d PO (may div TID)

      Topical: 3-5 g applied topically

      Next:

      Suggested Uses

      Blood pressure problems, arrhythmias, weak heart, epistaxis, PMS

      Previous
      Next:

      Interactions

      Interaction Checker

      and Shepherd's Purse

      No Results

         activity indicator 
        No Interactions Found
        Interactions Found

        Contraindicated

          Serious - Use Alternative

            Significant - Monitor Closely

              Minor

                All Interactions Sort By:
                 activity indicator 

                Contraindicated (0)

                  Serious - Use Alternative (2)

                  • calcium/magnesium/potassium/sodium oxybates

                    shepherd's purse, calcium/magnesium/potassium/sodium oxybates. Either increases effects of the other by pharmacodynamic synergism. Avoid or Use Alternate Drug. Profound sedation, respiratory depression, coma, and death may result if coadministered. Reserve concomitant prescribing of these drugs in patients for whom other treatment options are inadequate. Limit dosages and durations to the minimum required. Monitor closely for signs of respiratory depression and sedation.

                  • sodium oxybate

                    shepherd's purse, sodium oxybate. Either increases effects of the other by pharmacodynamic synergism. Avoid or Use Alternate Drug. Profound sedation, respiratory depression, coma, and death may result if coadministered. Reserve concomitant prescribing of these drugs in patients for whom other treatment options are inadequate. Limit dosages and durations to the minimum required. Monitor closely for signs of respiratory depression and sedation.

                  Monitor Closely (161)

                  • albuterol

                    shepherd's purse increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • alfentanil

                    alfentanil and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • alprazolam

                    alprazolam and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • amitriptyline

                    amitriptyline and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • amobarbital

                    amobarbital and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • amoxapine

                    amoxapine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • apomorphine

                    apomorphine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • arformoterol

                    shepherd's purse increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • aripiprazole

                    aripiprazole and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • armodafinil

                    shepherd's purse increases and armodafinil decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • azelastine

                    azelastine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • baclofen

                    baclofen and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • belladonna and opium

                    belladonna and opium and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • benperidol

                    benperidol and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • benzphetamine

                    shepherd's purse increases and benzphetamine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • brompheniramine

                    brompheniramine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • buprenorphine

                    buprenorphine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • buprenorphine buccal

                    buprenorphine buccal and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • butabarbital

                    butabarbital and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • butalbital

                    butalbital and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • butorphanol

                    butorphanol and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • caffeine

                    shepherd's purse increases and caffeine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • carbinoxamine

                    carbinoxamine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • carisoprodol

                    carisoprodol and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • chloral hydrate

                    chloral hydrate and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • chlordiazepoxide

                    chlordiazepoxide and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • chlorpheniramine

                    chlorpheniramine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • chlorpromazine

                    chlorpromazine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • chlorzoxazone

                    chlorzoxazone and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • cinnarizine

                    cinnarizine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • clemastine

                    clemastine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • clomipramine

                    clomipramine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • clonazepam

                    clonazepam and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • clorazepate

                    clorazepate and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • clozapine

                    clozapine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • codeine

                    codeine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • cyclizine

                    cyclizine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • cyclobenzaprine

                    cyclobenzaprine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • cyproheptadine

                    cyproheptadine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • dantrolene

                    dantrolene and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • desipramine

                    desipramine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • dexchlorpheniramine

                    dexchlorpheniramine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • dexfenfluramine

                    shepherd's purse increases and dexfenfluramine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • dexmedetomidine

                    dexmedetomidine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • dexmethylphenidate

                    shepherd's purse increases and dexmethylphenidate decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • dextroamphetamine

                    shepherd's purse increases and dextroamphetamine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • dextromoramide

                    dextromoramide and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • diamorphine

                    diamorphine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • diazepam

                    diazepam and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • diethylpropion

                    shepherd's purse increases and diethylpropion decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • difenoxin hcl

                    difenoxin hcl and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • diltiazem

                    shepherd's purse, diltiazem. Other (see comment). Use Caution/Monitor. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • dimenhydrinate

                    dimenhydrinate and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • diphenhydramine

                    diphenhydramine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • diphenoxylate hcl

                    diphenoxylate hcl and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • dipipanone

                    dipipanone and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • dobutamine

                    shepherd's purse increases and dobutamine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • dopamine

                    shepherd's purse increases and dopamine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • dopexamine

                    shepherd's purse increases and dopexamine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • doxepin

                    doxepin and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • doxylamine

                    doxylamine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • droperidol

                    droperidol and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • ephedrine

                    shepherd's purse increases and ephedrine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • epinephrine

                    shepherd's purse increases and epinephrine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • epinephrine racemic

                    shepherd's purse increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • estazolam

                    estazolam and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • ethanol

                    ethanol and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • etomidate

                    etomidate and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • fenfluramine

                    shepherd's purse increases and fenfluramine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • fluphenazine

                    fluphenazine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • flurazepam

                    flurazepam and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • formoterol

                    shepherd's purse increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • haloperidol

                    haloperidol and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • hydromorphone

                    hydromorphone and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • hydroxyzine

                    hydroxyzine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • iloperidone

                    iloperidone and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • imipramine

                    imipramine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • isoproterenol

                    shepherd's purse increases and isoproterenol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • ketotifen, ophthalmic

                    ketotifen, ophthalmic and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • levalbuterol

                    shepherd's purse increases and levalbuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • levorphanol

                    levorphanol and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • lisdexamfetamine

                    shepherd's purse increases and lisdexamfetamine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • lofepramine

                    lofepramine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • lofexidine

                    lofexidine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • loprazolam

                    loprazolam and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • lorazepam

                    lorazepam and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • lormetazepam

                    lormetazepam and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • loxapine

                    loxapine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • loxapine inhaled

                    loxapine inhaled and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • maprotiline

                    maprotiline and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • marijuana

                    marijuana and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • melatonin

                    melatonin and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • meperidine

                    meperidine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • meprobamate

                    meprobamate and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • metaproterenol

                    shepherd's purse increases and metaproterenol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • metaxalone

                    metaxalone and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • methadone

                    methadone and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • methamphetamine

                    shepherd's purse increases and methamphetamine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • methocarbamol

                    methocarbamol and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • methylenedioxymethamphetamine

                    shepherd's purse increases and methylenedioxymethamphetamine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • midazolam

                    midazolam and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • midodrine

                    shepherd's purse increases and midodrine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • mirtazapine

                    mirtazapine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • modafinil

                    shepherd's purse increases and modafinil decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • morphine

                    morphine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • motherwort

                    motherwort and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • moxonidine

                    moxonidine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • nabilone

                    nabilone and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • nalbuphine

                    nalbuphine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • norepinephrine

                    shepherd's purse increases and norepinephrine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • nortriptyline

                    nortriptyline and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • olanzapine

                    olanzapine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • opium tincture

                    opium tincture and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • orphenadrine

                    orphenadrine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • oxazepam

                    oxazepam and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • oxycodone

                    oxycodone and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • oxymorphone

                    oxymorphone and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • paliperidone

                    paliperidone and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • papaveretum

                    papaveretum and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • papaverine

                    papaverine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • pentazocine

                    pentazocine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • pentobarbital

                    pentobarbital and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • perphenazine

                    perphenazine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • phendimetrazine

                    shepherd's purse increases and phendimetrazine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • phenobarbital

                    phenobarbital and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • phentermine

                    shepherd's purse increases and phentermine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • phenylephrine

                    shepherd's purse increases and phenylephrine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • phenylephrine PO

                    shepherd's purse increases and phenylephrine PO decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor. .

                  • pholcodine

                    pholcodine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • pimozide

                    pimozide and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • pirbuterol

                    shepherd's purse increases and pirbuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • primidone

                    primidone and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • prochlorperazine

                    prochlorperazine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • promethazine

                    promethazine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • propylhexedrine

                    shepherd's purse increases and propylhexedrine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • protriptyline

                    protriptyline and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • quazepam

                    quazepam and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • quetiapine

                    quetiapine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • ramelteon

                    ramelteon and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • risperidone

                    risperidone and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • salmeterol

                    shepherd's purse increases and salmeterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • scullcap

                    scullcap and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • secobarbital

                    secobarbital and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • sufentanil

                    sufentanil and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • tapentadol

                    tapentadol and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • temazepam

                    temazepam and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • terbutaline

                    shepherd's purse increases and terbutaline decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • thioridazine

                    thioridazine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • thiothixene

                    thiothixene and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • topiramate

                    shepherd's purse and topiramate both increase sedation. Modify Therapy/Monitor Closely.

                  • tramadol

                    tramadol and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • trazodone

                    trazodone and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • triazolam

                    triazolam and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • triclofos

                    triclofos and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • trifluoperazine

                    trifluoperazine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • trimipramine

                    trimipramine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • triprolidine

                    triprolidine and shepherd's purse both increase sedation. Use Caution/Monitor.

                  • xylometazoline

                    shepherd's purse increases and xylometazoline decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • yohimbine

                    shepherd's purse increases and yohimbine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                  • ziconotide

                    shepherd's purse and ziconotide both increase sedation. Use Caution/Monitor.

                  • ziprasidone

                    ziprasidone and shepherd's purse both increase sedation. Use Caution/Monitor.

                  Minor (78)

                  • acebutolol

                    shepherd's purse, acebutolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • ambrisentan

                    shepherd's purse, ambrisentan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • amiloride

                    shepherd's purse, amiloride. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • amlodipine

                    shepherd's purse, amlodipine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • atenolol

                    shepherd's purse, atenolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • bendroflumethiazide

                    shepherd's purse, bendroflumethiazide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • betaxolol

                    shepherd's purse, betaxolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • bisoprolol

                    shepherd's purse, bisoprolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • bosentan

                    shepherd's purse, bosentan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • bumetanide

                    shepherd's purse, bumetanide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • candesartan

                    shepherd's purse, candesartan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • carvedilol

                    shepherd's purse, carvedilol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • celiprolol

                    shepherd's purse, celiprolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • chlorothiazide

                    shepherd's purse, chlorothiazide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • chlorthalidone

                    shepherd's purse, chlorthalidone. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • clevidipine

                    shepherd's purse, clevidipine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • clonidine

                    shepherd's purse, clonidine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • cyclopenthiazide

                    shepherd's purse, cyclopenthiazide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • digoxin

                    shepherd's purse, digoxin. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with cardiovascular therapy.

                  • drospirenone

                    shepherd's purse, drospirenone. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • enalapril

                    shepherd's purse, enalapril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • eplerenone

                    shepherd's purse, eplerenone. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • epoprostenol

                    shepherd's purse, epoprostenol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • eprosartan

                    shepherd's purse, eprosartan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • esmolol

                    shepherd's purse, esmolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • ethacrynic acid

                    shepherd's purse, ethacrynic acid. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • eucalyptus

                    eucalyptus and shepherd's purse both increase sedation. Minor/Significance Unknown.

                  • felodipine

                    shepherd's purse, felodipine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • fenoldopam

                    shepherd's purse, fenoldopam. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • fosinopril

                    shepherd's purse, fosinopril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • furosemide

                    shepherd's purse, furosemide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • guanfacine

                    shepherd's purse, guanfacine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • hydralazine

                    shepherd's purse, hydralazine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • hydrochlorothiazide

                    shepherd's purse, hydrochlorothiazide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • iloprost

                    shepherd's purse, iloprost. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • imidapril

                    shepherd's purse, imidapril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • indapamide

                    shepherd's purse, indapamide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • irbesartan

                    shepherd's purse, irbesartan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • isradipine

                    shepherd's purse, isradipine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • ketanserin

                    shepherd's purse, ketanserin. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • labetalol

                    shepherd's purse, labetalol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • levothyroxine

                    shepherd's purse decreases effects of levothyroxine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • liothyronine

                    shepherd's purse decreases effects of liothyronine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • lisinopril

                    shepherd's purse, lisinopril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • losartan

                    shepherd's purse, losartan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • mecamylamine

                    shepherd's purse, mecamylamine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • methyclothiazide

                    shepherd's purse, methyclothiazide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • metolazone

                    shepherd's purse, metolazone. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • metoprolol

                    shepherd's purse, metoprolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • metyrosine

                    shepherd's purse, metyrosine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • minoxidil

                    shepherd's purse, minoxidil. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • moexipril

                    shepherd's purse, moexipril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • moxonidine

                    shepherd's purse, moxonidine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • nadolol

                    shepherd's purse, nadolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • nebivolol

                    shepherd's purse, nebivolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • nicardipine

                    shepherd's purse, nicardipine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • nifedipine

                    shepherd's purse, nifedipine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • nisoldipine

                    shepherd's purse, nisoldipine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • olmesartan

                    shepherd's purse, olmesartan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • penbutolol

                    shepherd's purse, penbutolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • perindopril

                    shepherd's purse, perindopril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • pindolol

                    shepherd's purse, pindolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • propranolol

                    shepherd's purse, propranolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • quinapril

                    shepherd's purse, quinapril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • ramipril

                    shepherd's purse, ramipril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • sacubitril/valsartan

                    shepherd's purse, sacubitril/valsartan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • sage

                    sage and shepherd's purse both increase sedation. Minor/Significance Unknown.

                  • sotalol

                    shepherd's purse, sotalol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • spironolactone

                    shepherd's purse, spironolactone. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • telmisartan

                    shepherd's purse, telmisartan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • thyroid desiccated

                    shepherd's purse decreases effects of thyroid desiccated by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

                  • timolol

                    shepherd's purse, timolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • torsemide

                    shepherd's purse, torsemide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • trandolapril

                    shepherd's purse, trandolapril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • treprostinil

                    shepherd's purse, treprostinil. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • triamterene

                    shepherd's purse, triamterene. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • valsartan

                    shepherd's purse, valsartan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

                  • verapamil

                    shepherd's purse, verapamil. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

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                  Warnings

                  Contraindications

                  Pregnancy

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                  Pregnancy & Lactation

                  Pregnancy Category: do not use

                  Lactation: N/A

                  Pregnancy Categories

                  A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                  B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                  C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                  D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                  X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                  NA: Information not available.

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                  Pharmacology

                  Mechanism of Action

                  Influences blood pressure, boosts cardiac output/heart rate, promotes uterine contractions; contains saponins, bursinic acid, flavonoids, choline, beta carotene, and Vitamins B, C, and K

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                  Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
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