Shepherd's Purse (Herb/Suppl)

Brand and Other Names:blindweed, caseweed, more...cocowort, lady's purse, mothers heart, pepper & salt, pickpocket, poor man's parmacettie, St James weed, witches' pouches
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Suggested Dosing

Insufficent reliable evidence on effectiveness

Oral: 1-4 g PO TID

Crushed herb: 10-15 g/d PO (may div TID)

Liquid extract: 5-8 g/d PO (may div TID)

Topical: 3-5 g applied topically

Next:

Suggested Uses

Blood pressure problems, arrhythmias, weak heart, epistaxis, PMS

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Interactions

Interaction Checker

and Shepherd's Purse

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            All Interactions Sort By:
             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (2)

              • calcium/magnesium/potassium/sodium oxybates

                shepherd's purse, calcium/magnesium/potassium/sodium oxybates. Either increases effects of the other by pharmacodynamic synergism. Avoid or Use Alternate Drug. Profound sedation, respiratory depression, coma, and death may result if coadministered. Reserve concomitant prescribing of these drugs in patients for whom other treatment options are inadequate. Limit dosages and durations to the minimum required. Monitor closely for signs of respiratory depression and sedation.

              • sodium oxybate

                shepherd's purse, sodium oxybate. Either increases effects of the other by pharmacodynamic synergism. Avoid or Use Alternate Drug. Profound sedation, respiratory depression, coma, and death may result if coadministered. Reserve concomitant prescribing of these drugs in patients for whom other treatment options are inadequate. Limit dosages and durations to the minimum required. Monitor closely for signs of respiratory depression and sedation.

              Monitor Closely (161)

              • albuterol

                shepherd's purse increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • alfentanil

                alfentanil and shepherd's purse both increase sedation. Use Caution/Monitor.

              • alprazolam

                alprazolam and shepherd's purse both increase sedation. Use Caution/Monitor.

              • amitriptyline

                amitriptyline and shepherd's purse both increase sedation. Use Caution/Monitor.

              • amobarbital

                amobarbital and shepherd's purse both increase sedation. Use Caution/Monitor.

              • amoxapine

                amoxapine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • apomorphine

                apomorphine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • arformoterol

                shepherd's purse increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • aripiprazole

                aripiprazole and shepherd's purse both increase sedation. Use Caution/Monitor.

              • armodafinil

                shepherd's purse increases and armodafinil decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • azelastine

                azelastine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • baclofen

                baclofen and shepherd's purse both increase sedation. Use Caution/Monitor.

              • belladonna and opium

                belladonna and opium and shepherd's purse both increase sedation. Use Caution/Monitor.

              • benperidol

                benperidol and shepherd's purse both increase sedation. Use Caution/Monitor.

              • benzphetamine

                shepherd's purse increases and benzphetamine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • brompheniramine

                brompheniramine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • buprenorphine

                buprenorphine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • buprenorphine buccal

                buprenorphine buccal and shepherd's purse both increase sedation. Use Caution/Monitor.

              • butabarbital

                butabarbital and shepherd's purse both increase sedation. Use Caution/Monitor.

              • butalbital

                butalbital and shepherd's purse both increase sedation. Use Caution/Monitor.

              • butorphanol

                butorphanol and shepherd's purse both increase sedation. Use Caution/Monitor.

              • caffeine

                shepherd's purse increases and caffeine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • carbinoxamine

                carbinoxamine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • carisoprodol

                carisoprodol and shepherd's purse both increase sedation. Use Caution/Monitor.

              • chloral hydrate

                chloral hydrate and shepherd's purse both increase sedation. Use Caution/Monitor.

              • chlordiazepoxide

                chlordiazepoxide and shepherd's purse both increase sedation. Use Caution/Monitor.

              • chlorpheniramine

                chlorpheniramine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • chlorpromazine

                chlorpromazine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • chlorzoxazone

                chlorzoxazone and shepherd's purse both increase sedation. Use Caution/Monitor.

              • cinnarizine

                cinnarizine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • clemastine

                clemastine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • clomipramine

                clomipramine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • clonazepam

                clonazepam and shepherd's purse both increase sedation. Use Caution/Monitor.

              • clorazepate

                clorazepate and shepherd's purse both increase sedation. Use Caution/Monitor.

              • clozapine

                clozapine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • codeine

                codeine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • cyclizine

                cyclizine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • cyclobenzaprine

                cyclobenzaprine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • cyproheptadine

                cyproheptadine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • dantrolene

                dantrolene and shepherd's purse both increase sedation. Use Caution/Monitor.

              • desipramine

                desipramine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • dexchlorpheniramine

                dexchlorpheniramine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • dexfenfluramine

                shepherd's purse increases and dexfenfluramine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • dexmedetomidine

                dexmedetomidine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • dexmethylphenidate

                shepherd's purse increases and dexmethylphenidate decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • dextroamphetamine

                shepherd's purse increases and dextroamphetamine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • dextromoramide

                dextromoramide and shepherd's purse both increase sedation. Use Caution/Monitor.

              • diamorphine

                diamorphine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • diazepam

                diazepam and shepherd's purse both increase sedation. Use Caution/Monitor.

              • diethylpropion

                shepherd's purse increases and diethylpropion decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • difenoxin hcl

                difenoxin hcl and shepherd's purse both increase sedation. Use Caution/Monitor.

              • diltiazem

                shepherd's purse, diltiazem. Other (see comment). Use Caution/Monitor. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • dimenhydrinate

                dimenhydrinate and shepherd's purse both increase sedation. Use Caution/Monitor.

              • diphenhydramine

                diphenhydramine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • diphenoxylate hcl

                diphenoxylate hcl and shepherd's purse both increase sedation. Use Caution/Monitor.

              • dipipanone

                dipipanone and shepherd's purse both increase sedation. Use Caution/Monitor.

              • dobutamine

                shepherd's purse increases and dobutamine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • dopamine

                shepherd's purse increases and dopamine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • dopexamine

                shepherd's purse increases and dopexamine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • doxepin

                doxepin and shepherd's purse both increase sedation. Use Caution/Monitor.

              • doxylamine

                doxylamine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • droperidol

                droperidol and shepherd's purse both increase sedation. Use Caution/Monitor.

              • ephedrine

                shepherd's purse increases and ephedrine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • epinephrine

                shepherd's purse increases and epinephrine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • epinephrine racemic

                shepherd's purse increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • estazolam

                estazolam and shepherd's purse both increase sedation. Use Caution/Monitor.

              • ethanol

                ethanol and shepherd's purse both increase sedation. Use Caution/Monitor.

              • etomidate

                etomidate and shepherd's purse both increase sedation. Use Caution/Monitor.

              • fenfluramine

                shepherd's purse increases and fenfluramine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • fluphenazine

                fluphenazine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • flurazepam

                flurazepam and shepherd's purse both increase sedation. Use Caution/Monitor.

              • formoterol

                shepherd's purse increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • haloperidol

                haloperidol and shepherd's purse both increase sedation. Use Caution/Monitor.

              • hydromorphone

                hydromorphone and shepherd's purse both increase sedation. Use Caution/Monitor.

              • hydroxyzine

                hydroxyzine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • iloperidone

                iloperidone and shepherd's purse both increase sedation. Use Caution/Monitor.

              • imipramine

                imipramine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • isoproterenol

                shepherd's purse increases and isoproterenol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • ketotifen, ophthalmic

                ketotifen, ophthalmic and shepherd's purse both increase sedation. Use Caution/Monitor.

              • levalbuterol

                shepherd's purse increases and levalbuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • levorphanol

                levorphanol and shepherd's purse both increase sedation. Use Caution/Monitor.

              • lisdexamfetamine

                shepherd's purse increases and lisdexamfetamine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • lofepramine

                lofepramine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • lofexidine

                lofexidine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • loprazolam

                loprazolam and shepherd's purse both increase sedation. Use Caution/Monitor.

              • lorazepam

                lorazepam and shepherd's purse both increase sedation. Use Caution/Monitor.

              • lormetazepam

                lormetazepam and shepherd's purse both increase sedation. Use Caution/Monitor.

              • loxapine

                loxapine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • loxapine inhaled

                loxapine inhaled and shepherd's purse both increase sedation. Use Caution/Monitor.

              • maprotiline

                maprotiline and shepherd's purse both increase sedation. Use Caution/Monitor.

              • marijuana

                marijuana and shepherd's purse both increase sedation. Use Caution/Monitor.

              • melatonin

                melatonin and shepherd's purse both increase sedation. Use Caution/Monitor.

              • meperidine

                meperidine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • meprobamate

                meprobamate and shepherd's purse both increase sedation. Use Caution/Monitor.

              • metaproterenol

                shepherd's purse increases and metaproterenol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • metaxalone

                metaxalone and shepherd's purse both increase sedation. Use Caution/Monitor.

              • methadone

                methadone and shepherd's purse both increase sedation. Use Caution/Monitor.

              • methamphetamine

                shepherd's purse increases and methamphetamine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • methocarbamol

                methocarbamol and shepherd's purse both increase sedation. Use Caution/Monitor.

              • methylenedioxymethamphetamine

                shepherd's purse increases and methylenedioxymethamphetamine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • midazolam

                midazolam and shepherd's purse both increase sedation. Use Caution/Monitor.

              • midodrine

                shepherd's purse increases and midodrine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • mirtazapine

                mirtazapine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • modafinil

                shepherd's purse increases and modafinil decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • morphine

                morphine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • motherwort

                motherwort and shepherd's purse both increase sedation. Use Caution/Monitor.

              • moxonidine

                moxonidine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • nabilone

                nabilone and shepherd's purse both increase sedation. Use Caution/Monitor.

              • nalbuphine

                nalbuphine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • norepinephrine

                shepherd's purse increases and norepinephrine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • nortriptyline

                nortriptyline and shepherd's purse both increase sedation. Use Caution/Monitor.

              • olanzapine

                olanzapine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • opium tincture

                opium tincture and shepherd's purse both increase sedation. Use Caution/Monitor.

              • orphenadrine

                orphenadrine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • oxazepam

                oxazepam and shepherd's purse both increase sedation. Use Caution/Monitor.

              • oxycodone

                oxycodone and shepherd's purse both increase sedation. Use Caution/Monitor.

              • oxymorphone

                oxymorphone and shepherd's purse both increase sedation. Use Caution/Monitor.

              • paliperidone

                paliperidone and shepherd's purse both increase sedation. Use Caution/Monitor.

              • papaveretum

                papaveretum and shepherd's purse both increase sedation. Use Caution/Monitor.

              • papaverine

                papaverine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • pentazocine

                pentazocine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • pentobarbital

                pentobarbital and shepherd's purse both increase sedation. Use Caution/Monitor.

              • perphenazine

                perphenazine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • phendimetrazine

                shepherd's purse increases and phendimetrazine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • phenobarbital

                phenobarbital and shepherd's purse both increase sedation. Use Caution/Monitor.

              • phentermine

                shepherd's purse increases and phentermine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • phenylephrine

                shepherd's purse increases and phenylephrine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • phenylephrine PO

                shepherd's purse increases and phenylephrine PO decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor. .

              • pholcodine

                pholcodine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • pimozide

                pimozide and shepherd's purse both increase sedation. Use Caution/Monitor.

              • pirbuterol

                shepherd's purse increases and pirbuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • primidone

                primidone and shepherd's purse both increase sedation. Use Caution/Monitor.

              • prochlorperazine

                prochlorperazine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • promethazine

                promethazine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • propylhexedrine

                shepherd's purse increases and propylhexedrine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • protriptyline

                protriptyline and shepherd's purse both increase sedation. Use Caution/Monitor.

              • quazepam

                quazepam and shepherd's purse both increase sedation. Use Caution/Monitor.

              • quetiapine

                quetiapine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • ramelteon

                ramelteon and shepherd's purse both increase sedation. Use Caution/Monitor.

              • risperidone

                risperidone and shepherd's purse both increase sedation. Use Caution/Monitor.

              • salmeterol

                shepherd's purse increases and salmeterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • scullcap

                scullcap and shepherd's purse both increase sedation. Use Caution/Monitor.

              • secobarbital

                secobarbital and shepherd's purse both increase sedation. Use Caution/Monitor.

              • sufentanil

                sufentanil and shepherd's purse both increase sedation. Use Caution/Monitor.

              • tapentadol

                tapentadol and shepherd's purse both increase sedation. Use Caution/Monitor.

              • temazepam

                temazepam and shepherd's purse both increase sedation. Use Caution/Monitor.

              • terbutaline

                shepherd's purse increases and terbutaline decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • thioridazine

                thioridazine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • thiothixene

                thiothixene and shepherd's purse both increase sedation. Use Caution/Monitor.

              • topiramate

                shepherd's purse and topiramate both increase sedation. Modify Therapy/Monitor Closely.

              • tramadol

                tramadol and shepherd's purse both increase sedation. Use Caution/Monitor.

              • trazodone

                trazodone and shepherd's purse both increase sedation. Use Caution/Monitor.

              • triazolam

                triazolam and shepherd's purse both increase sedation. Use Caution/Monitor.

              • triclofos

                triclofos and shepherd's purse both increase sedation. Use Caution/Monitor.

              • trifluoperazine

                trifluoperazine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • trimipramine

                trimipramine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • triprolidine

                triprolidine and shepherd's purse both increase sedation. Use Caution/Monitor.

              • xylometazoline

                shepherd's purse increases and xylometazoline decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • yohimbine

                shepherd's purse increases and yohimbine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • ziconotide

                shepherd's purse and ziconotide both increase sedation. Use Caution/Monitor.

              • ziprasidone

                ziprasidone and shepherd's purse both increase sedation. Use Caution/Monitor.

              Minor (78)

              • acebutolol

                shepherd's purse, acebutolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • ambrisentan

                shepherd's purse, ambrisentan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • amiloride

                shepherd's purse, amiloride. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • amlodipine

                shepherd's purse, amlodipine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • atenolol

                shepherd's purse, atenolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • bendroflumethiazide

                shepherd's purse, bendroflumethiazide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • betaxolol

                shepherd's purse, betaxolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • bisoprolol

                shepherd's purse, bisoprolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • bosentan

                shepherd's purse, bosentan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • bumetanide

                shepherd's purse, bumetanide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • candesartan

                shepherd's purse, candesartan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • carvedilol

                shepherd's purse, carvedilol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • celiprolol

                shepherd's purse, celiprolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • chlorothiazide

                shepherd's purse, chlorothiazide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • chlorthalidone

                shepherd's purse, chlorthalidone. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • clevidipine

                shepherd's purse, clevidipine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • clonidine

                shepherd's purse, clonidine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • cyclopenthiazide

                shepherd's purse, cyclopenthiazide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • digoxin

                shepherd's purse, digoxin. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with cardiovascular therapy.

              • drospirenone

                shepherd's purse, drospirenone. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • enalapril

                shepherd's purse, enalapril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • eplerenone

                shepherd's purse, eplerenone. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • epoprostenol

                shepherd's purse, epoprostenol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • eprosartan

                shepherd's purse, eprosartan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • esmolol

                shepherd's purse, esmolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • ethacrynic acid

                shepherd's purse, ethacrynic acid. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • eucalyptus

                eucalyptus and shepherd's purse both increase sedation. Minor/Significance Unknown.

              • felodipine

                shepherd's purse, felodipine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • fenoldopam

                shepherd's purse, fenoldopam. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • fosinopril

                shepherd's purse, fosinopril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • furosemide

                shepherd's purse, furosemide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • guanfacine

                shepherd's purse, guanfacine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • hydralazine

                shepherd's purse, hydralazine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • hydrochlorothiazide

                shepherd's purse, hydrochlorothiazide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • iloprost

                shepherd's purse, iloprost. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • imidapril

                shepherd's purse, imidapril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • indapamide

                shepherd's purse, indapamide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • irbesartan

                shepherd's purse, irbesartan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • isradipine

                shepherd's purse, isradipine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • ketanserin

                shepherd's purse, ketanserin. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • labetalol

                shepherd's purse, labetalol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • levothyroxine

                shepherd's purse decreases effects of levothyroxine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

              • liothyronine

                shepherd's purse decreases effects of liothyronine by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

              • lisinopril

                shepherd's purse, lisinopril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • losartan

                shepherd's purse, losartan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • mecamylamine

                shepherd's purse, mecamylamine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • methyclothiazide

                shepherd's purse, methyclothiazide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • metolazone

                shepherd's purse, metolazone. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • metoprolol

                shepherd's purse, metoprolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • metyrosine

                shepherd's purse, metyrosine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • minoxidil

                shepherd's purse, minoxidil. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • moexipril

                shepherd's purse, moexipril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • moxonidine

                shepherd's purse, moxonidine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • nadolol

                shepherd's purse, nadolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • nebivolol

                shepherd's purse, nebivolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • nicardipine

                shepherd's purse, nicardipine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • nifedipine

                shepherd's purse, nifedipine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • nisoldipine

                shepherd's purse, nisoldipine. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • olmesartan

                shepherd's purse, olmesartan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • penbutolol

                shepherd's purse, penbutolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • perindopril

                shepherd's purse, perindopril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • pindolol

                shepherd's purse, pindolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • propranolol

                shepherd's purse, propranolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • quinapril

                shepherd's purse, quinapril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • ramipril

                shepherd's purse, ramipril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • sacubitril/valsartan

                shepherd's purse, sacubitril/valsartan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • sage

                sage and shepherd's purse both increase sedation. Minor/Significance Unknown.

              • sotalol

                shepherd's purse, sotalol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • spironolactone

                shepherd's purse, spironolactone. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • telmisartan

                shepherd's purse, telmisartan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • thyroid desiccated

                shepherd's purse decreases effects of thyroid desiccated by unspecified interaction mechanism. Minor/Significance Unknown. Theoretical interaction.

              • timolol

                shepherd's purse, timolol. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • torsemide

                shepherd's purse, torsemide. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • trandolapril

                shepherd's purse, trandolapril. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • treprostinil

                shepherd's purse, treprostinil. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • triamterene

                shepherd's purse, triamterene. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • valsartan

                shepherd's purse, valsartan. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

              • verapamil

                shepherd's purse, verapamil. Other (see comment). Minor/Significance Unknown. Comment: Theoretically, shepherd's purse may interfere with BP control.

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              Warnings

              Contraindications

              Pregnancy

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              Pregnancy & Lactation

              Pregnancy Category: do not use

              Lactation: N/A

              Pregnancy Categories

              A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

              B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

              C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

              D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

              X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

              NA: Information not available.

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              Pharmacology

              Mechanism of Action

              Influences blood pressure, boosts cardiac output/heart rate, promotes uterine contractions; contains saponins, bursinic acid, flavonoids, choline, beta carotene, and Vitamins B, C, and K

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              Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.