Dosing & Uses
Acceptable Safe Boron Intake
Natural product; no established RDA for this nutrient
1-20 mg/day; maximum tolerable intake ~20 mg/day
Acceptable Safe Boron Intake
1-3 years: 3 mg/day
3-8 years: 6 mg/day
8-13 years: 11 mg/day
13-18 years: 17 mg/day
Interactions
Interaction Checker
No Results
Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor
Contraindicated (0)
Serious - Use Alternative (0)
Monitor Closely (0)
Minor (8)
- bazedoxifene/conjugated estrogens
boron increases levels of bazedoxifene/conjugated estrogens by altering metabolism. Minor/Significance Unknown.
- conjugated estrogens
boron increases levels of conjugated estrogens by altering metabolism. Minor/Significance Unknown.
- conjugated estrogens, vaginal
boron increases levels of conjugated estrogens, vaginal by altering metabolism. Minor/Significance Unknown.
- estradiol
boron increases levels of estradiol by altering metabolism. Minor/Significance Unknown.
- estrogens conjugated synthetic
boron increases levels of estrogens conjugated synthetic by altering metabolism. Minor/Significance Unknown.
- estrogens esterified
boron increases levels of estrogens esterified by altering metabolism. Minor/Significance Unknown.
- estropipate
boron increases levels of estropipate by altering metabolism. Minor/Significance Unknown.
- mestranol
boron increases levels of mestranol by altering metabolism. Minor/Significance Unknown.
Adverse Effects
Frequency Not Defined
Blue/green discoloration of feces
Dermatitis
Diarrhea
Epigastric pain
Nausea
Renal impairment (rare: high dose)
Vomiting
Warnings
Contraindications
None reported
Cautions
Not yet fully established as required for human nutrition
There is no evidence that boron supplementation higher than levels found in diet is beneficial
Pregnancy & Lactation
Pregnancy Category: Safe when used below epected levels; not for intravaginal use as it has been associated with birth defects
Lactation: Not studied
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Has role in mineral metabolism & membrane function; may increase 17-ß-estradiol levels
Supplementation useful when dietary intake is inadequate
