Dosing & Uses
AdultPediatric
Major Depressive Disorder
Pending FDA approval for adjunctive treatment of major depressive disorder in patients with inadequate response to standard therapies
Safety and efficacy not established
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Pharmacology
Mechanism of Action
Buprenorphine: Partial mu-opioid receptor agonist and kappa-opioid receptor antagonist
Samidorphan: Mu-opioid antagonist
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Images
No images available for this drug.
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.