Blessed Thistle (Herb/Suppl)

Brand and Other Names:carbenia benedicta, bitter thistle, more...cardo santo, cnicin, cnicus benedictus, Holy Ghost herb, spotted thistle
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Suggested Dosing

Infusion: 2 g/150 mL water PO qD

Tea

1 cup (1.5-3 g/150 mL water) PO TID

4-6 g/d div TID PO (recommended by the German Commission E monograph)

Other Information

Tincture (1 g/5 mL): 10 mL PO qD

Fluidextract (1 g/mL): 2 mL PO qD OR 1.5-3 mL (1:1 in 25% alcohol) PO TID

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Suggested Uses

Indigestion, diarrhea, heartburn, poor appetite, flatulent dyspepsia, bronchial catarrh

Topical use: injured skin, gangrenous & indolent ulcers

Efficacy

Viral infections; antimicrobial effects in laboratory studies

Induced abortion: unclear safe and effective dosage

Increase breast milk flow: not recommended-see cautions

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Interactions

Interaction Checker

and Blessed Thistle

No Results

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    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (0)

                  Minor (14)

                  • aluminum hydroxide

                    blessed thistle decreases effects of aluminum hydroxide by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction.

                  • calcium carbonate

                    blessed thistle decreases effects of calcium carbonate by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction.

                  • cimetidine

                    blessed thistle decreases effects of cimetidine by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction.

                  • dexlansoprazole

                    blessed thistle decreases effects of dexlansoprazole by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction.

                  • esomeprazole

                    blessed thistle decreases effects of esomeprazole by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction.

                  • famotidine

                    blessed thistle decreases effects of famotidine by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction.

                  • ibuprofen/famotidine

                    blessed thistle decreases effects of ibuprofen/famotidine by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction.

                  • lansoprazole

                    blessed thistle decreases effects of lansoprazole by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction.

                  • nizatidine

                    blessed thistle decreases effects of nizatidine by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction.

                  • omeprazole

                    blessed thistle decreases effects of omeprazole by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction.

                  • pantoprazole

                    blessed thistle decreases effects of pantoprazole by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction.

                  • rabeprazole

                    blessed thistle decreases effects of rabeprazole by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction.

                  • sodium bicarbonate

                    blessed thistle decreases effects of sodium bicarbonate by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction.

                  • sodium citrate/citric acid

                    blessed thistle decreases effects of sodium citrate/citric acid by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction.

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                  Adverse Effects

                  Frequency Not Defined

                  GI irritation

                  Vomiting (>5 g dose)

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                  Warnings

                  Contraindications

                  Allergy to blesssed thistle

                  Crohn's disease, inflammatory bowel conditions, irritable bowel syndrome, ulcer

                  Pregnancy

                  Cautions

                  Do not confuse with milk thistle or other thistle products

                  Using to increase breast milk flow is discouraged since effect on nursing infant unknown

                  <18 years: not recommended

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                  Pregnancy & Lactation

                  Pregnancy Category: not recommended

                  Lactation: not recommended

                  Pregnancy Categories

                  A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                  B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                  C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                  D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                  X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                  NA: Information not available.

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                  Pharmacology

                  Metabolism: N/A

                  Excretion: N/A

                  Mechanism of Action

                  Active constituent: sesquiterpene lactones including cnicin

                  Stimulates secretion of saliva and gastric juices; antibacterial activity

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                  Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.