urea (OTC)

Brand and Other Names:Carmol 10, Keralac, more...Carmol 20, Carmol 40, Gordon's Urea, Aquacare, Ureacin 10, Ureacin 20, Utopic, Vanamide
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

cream

  • 10%
  • 20%
  • 30%
  • 35%
  • 40%
  • 41%
  • 45%
  • 50%

lotion

  • 10%
  • 20%
  • 25%
  • 35%
  • 40%
  • 45%

gel

  • 40%
  • 45%
  • 50%

suspension

  • 40%
  • 50%

solution

  • 50%

ointment

  • 10%
  • 20%
  • 50%

emulsion

  • 40%
  • 45%
  • 50%

aerosol, foam

  • 20%
  • 30%
  • 35%
  • 40%
  • 42%

Hyperkeratotic Skin Conditions

Indicated for hyperkeratotic conditions such as dry, rough skin; xerosis; ichthyosis; skin cracks and fissures; dermatitis; eczema; psoriasis; keratoses; and calluses

Apply topically to affected skin qDay or q8-12hr

Administration

Rub lotion/cream into skin until completely absorbed

Safety and efficacy not established

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Interactions

Interaction Checker

and urea

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            All Interactions Sort By:
             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (1)

                • collagenase

                  urea decreases effects of collagenase by increasing metabolism. Use Caution/Monitor.

                Minor (1)

                • vasopressin

                  urea increases effects of vasopressin by pharmacodynamic synergism. Minor/Significance Unknown.

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                Adverse Effects

                Frequency Not Defined

                Local irritation

                Transient stinging

                Rash

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                Warnings

                Contraindications

                Hypersensitivity

                Viral skin disease

                Cautions

                Ischemic skin necrosis reported with high concentration or irrigation

                Not for use near the eye

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                Pregnancy & Lactation

                Pregnancy category: C

                Lactation: Unknown

                Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

                Pregnancy Categories

                A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                NA: Information not available.

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                Pharmacology

                Mechanism of Action

                Elicits emollient and keratolytic effects; softens hyperkeratotic areas by disolving intracellular matrix, which subsequently loosens horny layer of the skin, or softens and debrides the nail plate

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                Images

                BRAND FORM. UNIT PRICE PILL IMAGE
                urea topical
                -
                39 % cream
                urea topical
                -
                50 % cream
                urea topical
                -
                45 % cream
                urea topical
                -
                45 % gel
                urea topical
                -
                40 % cream
                urea topical
                -
                40 % cream
                urea topical
                -
                40 % lotion
                urea topical
                -
                10 % cream
                urea topical
                -
                10 % lotion
                urea topical
                -
                41 % cream
                urea topical
                -
                40 % cream
                urea topical
                -
                40 % cream
                urea topical
                -
                40 % cream
                urea topical
                -
                40 % cream
                urea topical
                -
                35 % foam
                urea topical
                -
                20 % cream
                Kerafoam topical
                -
                42 % foam
                Kerafoam topical
                -
                30 % foam
                Kerafoam topical
                -
                42 % foam
                Kerafoam topical
                -
                30 % foam
                Umecta topical
                -
                40 % foam
                Uramaxin topical
                -
                45 % lotion
                Uramaxin topical
                -
                20 % foam
                Uramaxin topical
                -
                45 % cream
                Uramaxin topical
                -
                45 % gel
                Keralac topical
                -
                47 % cream
                Hydro 35 topical
                -
                35 % foam
                Uramaxin GT topical
                -
                45 % gel
                Utopic topical
                -
                41 % cream

                Copyright © 2010 First DataBank, Inc.

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                Patient Handout

                A Patient Handout is not currently available for this monograph.
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                Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.