urea (OTC)

Brand and Other Names:Carmol 10, Keralac, more...Carmol 20, Carmol 40, Gordon's Urea, Aquacare, Ureacin 10, Ureacin 20, Utopic, Vanamide
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

cream

  • 10%
  • 20%
  • 30%
  • 35%
  • 40%
  • 41%
  • 45%
  • 50%

lotion

  • 10%
  • 20%
  • 25%
  • 35%
  • 40%
  • 45%

gel

  • 40%
  • 45%
  • 50%

suspension

  • 40%
  • 50%

solution

  • 50%

ointment

  • 10%
  • 20%
  • 50%

emulsion

  • 40%
  • 45%
  • 50%

aerosol, foam

  • 20%
  • 30%
  • 35%
  • 40%
  • 42%
more...

Hyperkeratotic Skin Conditions

Indicated for hyperkeratotic conditions such as dry, rough skin; xerosis; ichthyosis; skin cracks and fissures; dermatitis; eczema; psoriasis; keratoses; and calluses

Apply topically to affected skin qDay or q8-12hr

Administration

Rub lotion/cream into skin until completely absorbed

Safety and efficacy not established

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Interactions

Interaction Checker

and urea

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Local irritation

            Transient stinging

            Rash

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            Warnings

            Contraindications

            Hypersensitivity

            Viral skin disease

            Cautions

            Ischemic skin necrosis reported with high concentration or irrigation

            Not for use near the eye

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            Pregnancy & Lactation

            Pregnancy category: C

            Lactation: Unknown

            Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Mechanism of Action

            Elicits emollient and keratolytic effects; softens hyperkeratotic areas by disolving intracellular matrix, which subsequently loosens horny layer of the skin, or softens and debrides the nail plate

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            Images

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            Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.