Dosing & Uses
Part a fixed-dose combination product with decitabine for treatment of myelodysplastic syndrome (MDS)
Pharmacology
Mechanism of Action
Cytidine deaminase (CDA) is a key enzyme in the catabolism of cytidines (eg, decitabine), since their deamination results in a loss of their pharmacological activity
Cedazuridine binds to and inhibits CDA, primarily found in the GI tract and liver that catalyzes the deamination of cytidine and cytidine analogs
When administered in combination with a cytidine, it specifically prevents its breakdown and increases its bioavailability and efficacy
Images
Formulary
Adding plans allows you to compare formulary status to other drugs in the same class.
To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.
Adding plans allows you to:
- View the formulary and any restrictions for each plan.
- Manage and view all your plans together – even plans in different states.
- Compare formulary status to other drugs in the same class.
- Access your plan list on any device – mobile or desktop.