Suggested Dosing
Oral dosing has not been studied in well conducted human trials. No specific dose can be recommended
Suggested Uses
Abdominal cramps, acne, angina pectoris, circulation problems, eczema/psoriasis, hepatitis (chronic), insomnia, ischemic stroke, menstrual problems, skin conditions, bruising, & wound healing
Efficacy
Ischemic Stroke: Preliminary research indicates that PO or IV may improve neurological deficits after acute ischemic stroke. More studies are needed
Interactions
Interaction Checker
No Results

Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor

Contraindicated (0)
Serious - Use Alternative (0)
Monitor Closely (15)
- alteplase
alteplase and danshen both increase anticoagulation. Modify Therapy/Monitor Closely.
- antithrombin alfa
antithrombin alfa and danshen both increase anticoagulation. Use Caution/Monitor.
- antithrombin III
antithrombin III and danshen both increase anticoagulation. Use Caution/Monitor.
- argatroban
argatroban and danshen both increase anticoagulation. Use Caution/Monitor.
- bemiparin
bemiparin and danshen both increase anticoagulation. Use Caution/Monitor.
- bivalirudin
bivalirudin and danshen both increase anticoagulation. Use Caution/Monitor.
- dabigatran
dabigatran and danshen both increase anticoagulation. Use Caution/Monitor.
- dalteparin
dalteparin and danshen both increase anticoagulation. Use Caution/Monitor.
- enoxaparin
enoxaparin and danshen both increase anticoagulation. Use Caution/Monitor.
- fondaparinux
fondaparinux and danshen both increase anticoagulation. Use Caution/Monitor.
- heparin
heparin and danshen both increase anticoagulation. Use Caution/Monitor.
- phenindione
phenindione and danshen both increase anticoagulation. Use Caution/Monitor.
- protamine
protamine and danshen both increase anticoagulation. Use Caution/Monitor.
- reteplase
reteplase and danshen both increase anticoagulation. Use Caution/Monitor.
- tenecteplase
tenecteplase and danshen both increase anticoagulation. Use Caution/Monitor.
Minor (56)
- aceclofenac
aceclofenac and danshen both increase anticoagulation. Minor/Significance Unknown.
- acemetacin
acemetacin and danshen both increase anticoagulation. Minor/Significance Unknown.
- agrimony
agrimony and danshen both increase anticoagulation. Minor/Significance Unknown.
- alfalfa
alfalfa and danshen both increase anticoagulation. Minor/Significance Unknown.
- American ginseng
American ginseng and danshen both increase anticoagulation. Minor/Significance Unknown.
- anamu
anamu and danshen both increase anticoagulation. Minor/Significance Unknown.
- aspirin
aspirin and danshen both increase anticoagulation. Minor/Significance Unknown.
- aspirin rectal
aspirin rectal and danshen both increase anticoagulation. Minor/Significance Unknown.
- aspirin/citric acid/sodium bicarbonate
aspirin/citric acid/sodium bicarbonate and danshen both increase anticoagulation. Minor/Significance Unknown.
- celecoxib
celecoxib and danshen both increase anticoagulation. Minor/Significance Unknown.
- choline magnesium trisalicylate
choline magnesium trisalicylate and danshen both increase anticoagulation. Minor/Significance Unknown.
- cinnamon
cinnamon and danshen both increase anticoagulation. Minor/Significance Unknown.
- cordyceps
cordyceps and danshen both increase anticoagulation. Minor/Significance Unknown.
- devil's claw
danshen and devil's claw both increase anticoagulation. Minor/Significance Unknown.
- diclofenac
diclofenac and danshen both increase anticoagulation. Minor/Significance Unknown.
- diflunisal
diflunisal and danshen both increase anticoagulation. Minor/Significance Unknown.
- dong quai
danshen and dong quai both increase anticoagulation. Minor/Significance Unknown.
- epoprostenol
danshen and epoprostenol both increase anticoagulation. Minor/Significance Unknown.
- etodolac
etodolac and danshen both increase anticoagulation. Minor/Significance Unknown.
- fennel
danshen and fennel both increase anticoagulation. Minor/Significance Unknown.
- fenoprofen
fenoprofen and danshen both increase anticoagulation. Minor/Significance Unknown.
- feverfew
danshen and feverfew both increase anticoagulation. Minor/Significance Unknown.
- flurbiprofen
flurbiprofen and danshen both increase anticoagulation. Minor/Significance Unknown.
- forskolin
danshen and forskolin both increase anticoagulation. Minor/Significance Unknown.
- garlic
danshen and garlic both increase anticoagulation. Minor/Significance Unknown.
- ginger
danshen and ginger both increase anticoagulation. Minor/Significance Unknown.
- ginkgo biloba
danshen and ginkgo biloba both increase anticoagulation. Minor/Significance Unknown.
- horse chestnut seed
danshen and horse chestnut seed both increase anticoagulation. Minor/Significance Unknown.
- ibuprofen
ibuprofen and danshen both increase anticoagulation. Minor/Significance Unknown.
- ibuprofen IV
ibuprofen IV and danshen both increase anticoagulation. Minor/Significance Unknown.
- indomethacin
indomethacin and danshen both increase anticoagulation. Minor/Significance Unknown.
- ketoprofen
ketoprofen and danshen both increase anticoagulation. Minor/Significance Unknown.
- ketorolac
ketorolac and danshen both increase anticoagulation. Minor/Significance Unknown.
- ketorolac intranasal
ketorolac intranasal and danshen both increase anticoagulation. Minor/Significance Unknown.
- lornoxicam
lornoxicam and danshen both increase anticoagulation. Minor/Significance Unknown.
- meclofenamate
meclofenamate and danshen both increase anticoagulation. Minor/Significance Unknown.
- mefenamic acid
mefenamic acid and danshen both increase anticoagulation. Minor/Significance Unknown.
- meloxicam
meloxicam and danshen both increase anticoagulation. Minor/Significance Unknown.
- mistletoe
danshen increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- nabumetone
nabumetone and danshen both increase anticoagulation. Minor/Significance Unknown.
- naproxen
naproxen and danshen both increase anticoagulation. Minor/Significance Unknown.
- nettle
danshen increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
- oxaprozin
oxaprozin and danshen both increase anticoagulation. Minor/Significance Unknown.
- panax ginseng
danshen and panax ginseng both increase anticoagulation. Minor/Significance Unknown.
- parecoxib
parecoxib and danshen both increase anticoagulation. Minor/Significance Unknown.
- pau d'arco
danshen and pau d'arco both increase anticoagulation. Minor/Significance Unknown.
- phytoestrogens
danshen and phytoestrogens both increase anticoagulation. Minor/Significance Unknown.
- piroxicam
piroxicam and danshen both increase anticoagulation. Minor/Significance Unknown.
- reishi
danshen and reishi both increase anticoagulation. Minor/Significance Unknown.
- salicylates (non-asa)
salicylates (non-asa) and danshen both increase anticoagulation. Minor/Significance Unknown.
- salsalate
salsalate and danshen both increase anticoagulation. Minor/Significance Unknown.
- Siberian ginseng
danshen and Siberian ginseng both increase anticoagulation. Minor/Significance Unknown.
- sulfasalazine
sulfasalazine and danshen both increase anticoagulation. Minor/Significance Unknown.
- sulindac
sulindac and danshen both increase anticoagulation. Minor/Significance Unknown.
- tolfenamic acid
tolfenamic acid and danshen both increase anticoagulation. Minor/Significance Unknown.
- tolmetin
tolmetin and danshen both increase anticoagulation. Minor/Significance Unknown.
Adverse Effects
Pruritis, reduced appetite, stomach upset
Warnings
Contraindications
Bleeding disorders
Pregnancy & Lactation
Pregnancy Category: avoid use
Lactation: avoid use
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Metabolism: N/A
Excretion: N/A
Mechanism of Action
Root has antispasmodic and antithrombotic properties; increases coronary flow rate