Danshen (Herb/Suppl)

Brand and Other Names:ch ih shen, huang ken, more...pin ma ts'ao, red sage, saliva root, salvia miltiorrhiza, Salvia miltiorrhiza Bunge, shu wei ts'ao, tan shen, tzu tan ken

Suggested Dosing

Oral dosing has not been studied in well conducted human trials. No specific dose can be recommended

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Suggested Uses

Abdominal cramps, acne, angina pectoris, circulation problems, eczema/psoriasis, hepatitis (chronic), insomnia, ischemic stroke, menstrual problems, skin conditions, bruising, & wound healing

Efficacy

Ischemic Stroke: Preliminary research indicates that PO or IV may improve neurological deficits after acute ischemic stroke. More studies are needed

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Interactions

Interaction Checker

and Danshen

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            All Interactions Sort By:
             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (15)

                • alteplase

                  alteplase and danshen both increase anticoagulation. Modify Therapy/Monitor Closely.

                • antithrombin alfa

                  antithrombin alfa and danshen both increase anticoagulation. Use Caution/Monitor.

                • antithrombin III

                  antithrombin III and danshen both increase anticoagulation. Use Caution/Monitor.

                • argatroban

                  argatroban and danshen both increase anticoagulation. Use Caution/Monitor.

                • bemiparin

                  bemiparin and danshen both increase anticoagulation. Use Caution/Monitor.

                • bivalirudin

                  bivalirudin and danshen both increase anticoagulation. Use Caution/Monitor.

                • dabigatran

                  dabigatran and danshen both increase anticoagulation. Use Caution/Monitor.

                • dalteparin

                  dalteparin and danshen both increase anticoagulation. Use Caution/Monitor.

                • enoxaparin

                  enoxaparin and danshen both increase anticoagulation. Use Caution/Monitor.

                • fondaparinux

                  fondaparinux and danshen both increase anticoagulation. Use Caution/Monitor.

                • heparin

                  heparin and danshen both increase anticoagulation. Use Caution/Monitor.

                • phenindione

                  phenindione and danshen both increase anticoagulation. Use Caution/Monitor.

                • protamine

                  protamine and danshen both increase anticoagulation. Use Caution/Monitor.

                • reteplase

                  reteplase and danshen both increase anticoagulation. Use Caution/Monitor.

                • tenecteplase

                  tenecteplase and danshen both increase anticoagulation. Use Caution/Monitor.

                Minor (56)

                • aceclofenac

                  aceclofenac and danshen both increase anticoagulation. Minor/Significance Unknown.

                • acemetacin

                  acemetacin and danshen both increase anticoagulation. Minor/Significance Unknown.

                • agrimony

                  agrimony and danshen both increase anticoagulation. Minor/Significance Unknown.

                • alfalfa

                  alfalfa and danshen both increase anticoagulation. Minor/Significance Unknown.

                • American ginseng

                  American ginseng and danshen both increase anticoagulation. Minor/Significance Unknown.

                • anamu

                  anamu and danshen both increase anticoagulation. Minor/Significance Unknown.

                • aspirin

                  aspirin and danshen both increase anticoagulation. Minor/Significance Unknown.

                • aspirin rectal

                  aspirin rectal and danshen both increase anticoagulation. Minor/Significance Unknown.

                • aspirin/citric acid/sodium bicarbonate

                  aspirin/citric acid/sodium bicarbonate and danshen both increase anticoagulation. Minor/Significance Unknown.

                • celecoxib

                  celecoxib and danshen both increase anticoagulation. Minor/Significance Unknown.

                • choline magnesium trisalicylate

                  choline magnesium trisalicylate and danshen both increase anticoagulation. Minor/Significance Unknown.

                • cinnamon

                  cinnamon and danshen both increase anticoagulation. Minor/Significance Unknown.

                • cordyceps

                  cordyceps and danshen both increase anticoagulation. Minor/Significance Unknown.

                • devil's claw

                  danshen and devil's claw both increase anticoagulation. Minor/Significance Unknown.

                • diclofenac

                  diclofenac and danshen both increase anticoagulation. Minor/Significance Unknown.

                • diflunisal

                  diflunisal and danshen both increase anticoagulation. Minor/Significance Unknown.

                • dong quai

                  danshen and dong quai both increase anticoagulation. Minor/Significance Unknown.

                • epoprostenol

                  danshen and epoprostenol both increase anticoagulation. Minor/Significance Unknown.

                • etodolac

                  etodolac and danshen both increase anticoagulation. Minor/Significance Unknown.

                • fennel

                  danshen and fennel both increase anticoagulation. Minor/Significance Unknown.

                • fenoprofen

                  fenoprofen and danshen both increase anticoagulation. Minor/Significance Unknown.

                • feverfew

                  danshen and feverfew both increase anticoagulation. Minor/Significance Unknown.

                • flurbiprofen

                  flurbiprofen and danshen both increase anticoagulation. Minor/Significance Unknown.

                • forskolin

                  danshen and forskolin both increase anticoagulation. Minor/Significance Unknown.

                • garlic

                  danshen and garlic both increase anticoagulation. Minor/Significance Unknown.

                • ginger

                  danshen and ginger both increase anticoagulation. Minor/Significance Unknown.

                • ginkgo biloba

                  danshen and ginkgo biloba both increase anticoagulation. Minor/Significance Unknown.

                • horse chestnut seed

                  danshen and horse chestnut seed both increase anticoagulation. Minor/Significance Unknown.

                • ibuprofen

                  ibuprofen and danshen both increase anticoagulation. Minor/Significance Unknown.

                • ibuprofen IV

                  ibuprofen IV and danshen both increase anticoagulation. Minor/Significance Unknown.

                • indomethacin

                  indomethacin and danshen both increase anticoagulation. Minor/Significance Unknown.

                • ketoprofen

                  ketoprofen and danshen both increase anticoagulation. Minor/Significance Unknown.

                • ketorolac

                  ketorolac and danshen both increase anticoagulation. Minor/Significance Unknown.

                • ketorolac intranasal

                  ketorolac intranasal and danshen both increase anticoagulation. Minor/Significance Unknown.

                • lornoxicam

                  lornoxicam and danshen both increase anticoagulation. Minor/Significance Unknown.

                • meclofenamate

                  meclofenamate and danshen both increase anticoagulation. Minor/Significance Unknown.

                • mefenamic acid

                  mefenamic acid and danshen both increase anticoagulation. Minor/Significance Unknown.

                • meloxicam

                  meloxicam and danshen both increase anticoagulation. Minor/Significance Unknown.

                • mistletoe

                  danshen increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                • nabumetone

                  nabumetone and danshen both increase anticoagulation. Minor/Significance Unknown.

                • naproxen

                  naproxen and danshen both increase anticoagulation. Minor/Significance Unknown.

                • nettle

                  danshen increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                • oxaprozin

                  oxaprozin and danshen both increase anticoagulation. Minor/Significance Unknown.

                • panax ginseng

                  danshen and panax ginseng both increase anticoagulation. Minor/Significance Unknown.

                • parecoxib

                  parecoxib and danshen both increase anticoagulation. Minor/Significance Unknown.

                • pau d'arco

                  danshen and pau d'arco both increase anticoagulation. Minor/Significance Unknown.

                • phytoestrogens

                  danshen and phytoestrogens both increase anticoagulation. Minor/Significance Unknown.

                • piroxicam

                  piroxicam and danshen both increase anticoagulation. Minor/Significance Unknown.

                • reishi

                  danshen and reishi both increase anticoagulation. Minor/Significance Unknown.

                • salicylates (non-asa)

                  salicylates (non-asa) and danshen both increase anticoagulation. Minor/Significance Unknown.

                • salsalate

                  salsalate and danshen both increase anticoagulation. Minor/Significance Unknown.

                • Siberian ginseng

                  danshen and Siberian ginseng both increase anticoagulation. Minor/Significance Unknown.

                • sulfasalazine

                  sulfasalazine and danshen both increase anticoagulation. Minor/Significance Unknown.

                • sulindac

                  sulindac and danshen both increase anticoagulation. Minor/Significance Unknown.

                • tolfenamic acid

                  tolfenamic acid and danshen both increase anticoagulation. Minor/Significance Unknown.

                • tolmetin

                  tolmetin and danshen both increase anticoagulation. Minor/Significance Unknown.

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                Adverse Effects

                Pruritis, reduced appetite, stomach upset

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                Warnings

                Contraindications

                Bleeding disorders

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                Pregnancy & Lactation

                Pregnancy Category: avoid use

                Lactation: avoid use

                Pregnancy Categories

                A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                NA: Information not available.

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                Pharmacology

                Metabolism: N/A

                Excretion: N/A

                Mechanism of Action

                Root has antispasmodic and antithrombotic properties; increases coronary flow rate

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                Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.