Indication-specific dosing for ch ih shen, huang ken, pin ma ts'ao danshen in combination, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.

Sections

Sections Danshen
Suggested Dosing
Suggested Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology

Suggested Dosing

Oral dosing has not been studied in well conducted human trials. No specific dose can be recommended

Suggested Uses

Abdominal cramps, acne, angina pectoris, circulation problems, eczema/psoriasis, hepatitis (chronic), insomnia, ischemic stroke, menstrual problems, skin conditions, bruising, & wound healing

Efficacy

Ischemic Stroke: Preliminary research indicates that PO or IV may improve neurological deficits after acute ischemic stroke. More studies are needed

Interaction Checker

Enter a drug name and Danshen

No Results

No Interactions Found

Interactions Found

Contraindicated

Serious - Use Alternative

Significant - Monitor Closely

Minor

All Interactions Sort By:

Contraindicated (0)

Serious - Use Alternative (0)

Monitor Closely (15)

alteplase
alteplase and danshen both increase anticoagulation. Modify Therapy/Monitor Closely.
antithrombin alfa
antithrombin alfa and danshen both increase anticoagulation. Use Caution/Monitor.
antithrombin III
antithrombin III and danshen both increase anticoagulation. Use Caution/Monitor.
argatroban
argatroban and danshen both increase anticoagulation. Use Caution/Monitor.
bemiparin
bemiparin and danshen both increase anticoagulation. Use Caution/Monitor.
bivalirudin
bivalirudin and danshen both increase anticoagulation. Use Caution/Monitor.
dabigatran
dabigatran and danshen both increase anticoagulation. Use Caution/Monitor.
dalteparin
dalteparin and danshen both increase anticoagulation. Use Caution/Monitor.
enoxaparin
enoxaparin and danshen both increase anticoagulation. Use Caution/Monitor.
fondaparinux
fondaparinux and danshen both increase anticoagulation. Use Caution/Monitor.
heparin
heparin and danshen both increase anticoagulation. Use Caution/Monitor.
phenindione
phenindione and danshen both increase anticoagulation. Use Caution/Monitor.
protamine
protamine and danshen both increase anticoagulation. Use Caution/Monitor.
reteplase
reteplase and danshen both increase anticoagulation. Use Caution/Monitor.
tenecteplase
tenecteplase and danshen both increase anticoagulation. Use Caution/Monitor.

Minor (56)

aceclofenac
aceclofenac and danshen both increase anticoagulation. Minor/Significance Unknown.
acemetacin
acemetacin and danshen both increase anticoagulation. Minor/Significance Unknown.
agrimony
agrimony and danshen both increase anticoagulation. Minor/Significance Unknown.
alfalfa
alfalfa and danshen both increase anticoagulation. Minor/Significance Unknown.
American ginseng
American ginseng and danshen both increase anticoagulation. Minor/Significance Unknown.
anamu
anamu and danshen both increase anticoagulation. Minor/Significance Unknown.
aspirin
aspirin and danshen both increase anticoagulation. Minor/Significance Unknown.
aspirin rectal
aspirin rectal and danshen both increase anticoagulation. Minor/Significance Unknown.
aspirin/citric acid/sodium bicarbonate
aspirin/citric acid/sodium bicarbonate and danshen both increase anticoagulation. Minor/Significance Unknown.
celecoxib
celecoxib and danshen both increase anticoagulation. Minor/Significance Unknown.
choline magnesium trisalicylate
choline magnesium trisalicylate and danshen both increase anticoagulation. Minor/Significance Unknown.
cinnamon
cinnamon and danshen both increase anticoagulation. Minor/Significance Unknown.
cordyceps
cordyceps and danshen both increase anticoagulation. Minor/Significance Unknown.
devil's claw
danshen and devil's claw both increase anticoagulation. Minor/Significance Unknown.
diclofenac
diclofenac and danshen both increase anticoagulation. Minor/Significance Unknown.
diflunisal
diflunisal and danshen both increase anticoagulation. Minor/Significance Unknown.
dong quai
danshen and dong quai both increase anticoagulation. Minor/Significance Unknown.
epoprostenol
danshen and epoprostenol both increase anticoagulation. Minor/Significance Unknown.
etodolac
etodolac and danshen both increase anticoagulation. Minor/Significance Unknown.
fennel
danshen and fennel both increase anticoagulation. Minor/Significance Unknown.
fenoprofen
fenoprofen and danshen both increase anticoagulation. Minor/Significance Unknown.
feverfew
danshen and feverfew both increase anticoagulation. Minor/Significance Unknown.
flurbiprofen
flurbiprofen and danshen both increase anticoagulation. Minor/Significance Unknown.
forskolin
danshen and forskolin both increase anticoagulation. Minor/Significance Unknown.
garlic
danshen and garlic both increase anticoagulation. Minor/Significance Unknown.
ginger
danshen and ginger both increase anticoagulation. Minor/Significance Unknown.
ginkgo biloba
danshen and ginkgo biloba both increase anticoagulation. Minor/Significance Unknown.
horse chestnut seed
danshen and horse chestnut seed both increase anticoagulation. Minor/Significance Unknown.
ibuprofen
ibuprofen and danshen both increase anticoagulation. Minor/Significance Unknown.
ibuprofen IV
ibuprofen IV and danshen both increase anticoagulation. Minor/Significance Unknown.
indomethacin
indomethacin and danshen both increase anticoagulation. Minor/Significance Unknown.
ketoprofen
ketoprofen and danshen both increase anticoagulation. Minor/Significance Unknown.
ketorolac
ketorolac and danshen both increase anticoagulation. Minor/Significance Unknown.
ketorolac intranasal
ketorolac intranasal and danshen both increase anticoagulation. Minor/Significance Unknown.
lornoxicam
lornoxicam and danshen both increase anticoagulation. Minor/Significance Unknown.
meclofenamate
meclofenamate and danshen both increase anticoagulation. Minor/Significance Unknown.
mefenamic acid
mefenamic acid and danshen both increase anticoagulation. Minor/Significance Unknown.
meloxicam
meloxicam and danshen both increase anticoagulation. Minor/Significance Unknown.
mistletoe
danshen increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
nabumetone
nabumetone and danshen both increase anticoagulation. Minor/Significance Unknown.
naproxen
naproxen and danshen both increase anticoagulation. Minor/Significance Unknown.
nettle
danshen increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
oxaprozin
oxaprozin and danshen both increase anticoagulation. Minor/Significance Unknown.
panax ginseng
danshen and panax ginseng both increase anticoagulation. Minor/Significance Unknown.
parecoxib
parecoxib and danshen both increase anticoagulation. Minor/Significance Unknown.
pau d'arco
danshen and pau d'arco both increase anticoagulation. Minor/Significance Unknown.
phytoestrogens
danshen and phytoestrogens both increase anticoagulation. Minor/Significance Unknown.
piroxicam
piroxicam and danshen both increase anticoagulation. Minor/Significance Unknown.
reishi
danshen and reishi both increase anticoagulation. Minor/Significance Unknown.
salicylates (non-asa)
salicylates (non-asa) and danshen both increase anticoagulation. Minor/Significance Unknown.
salsalate
salsalate and danshen both increase anticoagulation. Minor/Significance Unknown.
Siberian ginseng
danshen and Siberian ginseng both increase anticoagulation. Minor/Significance Unknown.
sulfasalazine
sulfasalazine and danshen both increase anticoagulation. Minor/Significance Unknown.
sulindac
sulindac and danshen both increase anticoagulation. Minor/Significance Unknown.
tolfenamic acid
tolfenamic acid and danshen both increase anticoagulation. Minor/Significance Unknown.
tolmetin
tolmetin and danshen both increase anticoagulation. Minor/Significance Unknown.

aceclofenac
Minor (1)aceclofenac and danshen both increase anticoagulation. Minor/Significance Unknown.
acemetacin
Minor (1)acemetacin and danshen both increase anticoagulation. Minor/Significance Unknown.
agrimony
Minor (1)agrimony and danshen both increase anticoagulation. Minor/Significance Unknown.
alfalfa
Minor (1)alfalfa and danshen both increase anticoagulation. Minor/Significance Unknown.
alteplase
Monitor Closely (1)alteplase and danshen both increase anticoagulation. Modify Therapy/Monitor Closely.
American ginseng
Minor (1)American ginseng and danshen both increase anticoagulation. Minor/Significance Unknown.
anamu
Minor (1)anamu and danshen both increase anticoagulation. Minor/Significance Unknown.
antithrombin alfa
Monitor Closely (1)antithrombin alfa and danshen both increase anticoagulation. Use Caution/Monitor.
antithrombin III
Monitor Closely (1)antithrombin III and danshen both increase anticoagulation. Use Caution/Monitor.
argatroban
Monitor Closely (1)argatroban and danshen both increase anticoagulation. Use Caution/Monitor.
aspirin
Minor (1)aspirin and danshen both increase anticoagulation. Minor/Significance Unknown.
aspirin rectal
Minor (1)aspirin rectal and danshen both increase anticoagulation. Minor/Significance Unknown.
aspirin/citric acid/sodium bicarbonate
Minor (1)aspirin/citric acid/sodium bicarbonate and danshen both increase anticoagulation. Minor/Significance Unknown.
bemiparin
Monitor Closely (1)bemiparin and danshen both increase anticoagulation. Use Caution/Monitor.
bivalirudin
Monitor Closely (1)bivalirudin and danshen both increase anticoagulation. Use Caution/Monitor.
celecoxib
Minor (1)celecoxib and danshen both increase anticoagulation. Minor/Significance Unknown.
choline magnesium trisalicylate
Minor (1)choline magnesium trisalicylate and danshen both increase anticoagulation. Minor/Significance Unknown.
cinnamon
Minor (1)cinnamon and danshen both increase anticoagulation. Minor/Significance Unknown.
cordyceps
Minor (1)cordyceps and danshen both increase anticoagulation. Minor/Significance Unknown.
dabigatran
Monitor Closely (1)dabigatran and danshen both increase anticoagulation. Use Caution/Monitor.
dalteparin
Monitor Closely (1)dalteparin and danshen both increase anticoagulation. Use Caution/Monitor.
devil's claw
Minor (1)danshen and devil's claw both increase anticoagulation. Minor/Significance Unknown.
diclofenac
Minor (1)diclofenac and danshen both increase anticoagulation. Minor/Significance Unknown.
diflunisal
Minor (1)diflunisal and danshen both increase anticoagulation. Minor/Significance Unknown.
dong quai
Minor (1)danshen and dong quai both increase anticoagulation. Minor/Significance Unknown.
enoxaparin
Monitor Closely (1)enoxaparin and danshen both increase anticoagulation. Use Caution/Monitor.
epoprostenol
Minor (1)danshen and epoprostenol both increase anticoagulation. Minor/Significance Unknown.
etodolac
Minor (1)etodolac and danshen both increase anticoagulation. Minor/Significance Unknown.
fennel
Minor (1)danshen and fennel both increase anticoagulation. Minor/Significance Unknown.
fenoprofen
Minor (1)fenoprofen and danshen both increase anticoagulation. Minor/Significance Unknown.
feverfew
Minor (1)danshen and feverfew both increase anticoagulation. Minor/Significance Unknown.
flurbiprofen
Minor (1)flurbiprofen and danshen both increase anticoagulation. Minor/Significance Unknown.
fondaparinux
Monitor Closely (1)fondaparinux and danshen both increase anticoagulation. Use Caution/Monitor.
forskolin
Minor (1)danshen and forskolin both increase anticoagulation. Minor/Significance Unknown.
garlic
Minor (1)danshen and garlic both increase anticoagulation. Minor/Significance Unknown.
ginger
Minor (1)danshen and ginger both increase anticoagulation. Minor/Significance Unknown.
ginkgo biloba
Minor (1)danshen and ginkgo biloba both increase anticoagulation. Minor/Significance Unknown.
heparin
Monitor Closely (1)heparin and danshen both increase anticoagulation. Use Caution/Monitor.
horse chestnut seed
Minor (1)danshen and horse chestnut seed both increase anticoagulation. Minor/Significance Unknown.
ibuprofen
Minor (1)ibuprofen and danshen both increase anticoagulation. Minor/Significance Unknown.
ibuprofen IV
Minor (1)ibuprofen IV and danshen both increase anticoagulation. Minor/Significance Unknown.
indomethacin
Minor (1)indomethacin and danshen both increase anticoagulation. Minor/Significance Unknown.
ketoprofen
Minor (1)ketoprofen and danshen both increase anticoagulation. Minor/Significance Unknown.
ketorolac
Minor (1)ketorolac and danshen both increase anticoagulation. Minor/Significance Unknown.
ketorolac intranasal
Minor (1)ketorolac intranasal and danshen both increase anticoagulation. Minor/Significance Unknown.
lornoxicam
Minor (1)lornoxicam and danshen both increase anticoagulation. Minor/Significance Unknown.
meclofenamate
Minor (1)meclofenamate and danshen both increase anticoagulation. Minor/Significance Unknown.
mefenamic acid
Minor (1)mefenamic acid and danshen both increase anticoagulation. Minor/Significance Unknown.
meloxicam
Minor (1)meloxicam and danshen both increase anticoagulation. Minor/Significance Unknown.
mistletoe
Minor (1)danshen increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
nabumetone
Minor (1)nabumetone and danshen both increase anticoagulation. Minor/Significance Unknown.
naproxen
Minor (1)naproxen and danshen both increase anticoagulation. Minor/Significance Unknown.
nettle
Minor (1)danshen increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.
oxaprozin
Minor (1)oxaprozin and danshen both increase anticoagulation. Minor/Significance Unknown.
panax ginseng
Minor (1)danshen and panax ginseng both increase anticoagulation. Minor/Significance Unknown.
parecoxib
Minor (1)parecoxib and danshen both increase anticoagulation. Minor/Significance Unknown.
pau d'arco
Minor (1)danshen and pau d'arco both increase anticoagulation. Minor/Significance Unknown.
phenindione
Monitor Closely (1)phenindione and danshen both increase anticoagulation. Use Caution/Monitor.
phytoestrogens
Minor (1)danshen and phytoestrogens both increase anticoagulation. Minor/Significance Unknown.
piroxicam
Minor (1)piroxicam and danshen both increase anticoagulation. Minor/Significance Unknown.
protamine
Monitor Closely (1)protamine and danshen both increase anticoagulation. Use Caution/Monitor.
reishi
Minor (1)danshen and reishi both increase anticoagulation. Minor/Significance Unknown.
reteplase
Monitor Closely (1)reteplase and danshen both increase anticoagulation. Use Caution/Monitor.
salicylates (non-asa)
Minor (1)salicylates (non-asa) and danshen both increase anticoagulation. Minor/Significance Unknown.
salsalate
Minor (1)salsalate and danshen both increase anticoagulation. Minor/Significance Unknown.
Siberian ginseng
Minor (1)danshen and Siberian ginseng both increase anticoagulation. Minor/Significance Unknown.
sulfasalazine
Minor (1)sulfasalazine and danshen both increase anticoagulation. Minor/Significance Unknown.
sulindac
Minor (1)sulindac and danshen both increase anticoagulation. Minor/Significance Unknown.
tenecteplase
Monitor Closely (1)tenecteplase and danshen both increase anticoagulation. Use Caution/Monitor.
tolfenamic acid
Minor (1)tolfenamic acid and danshen both increase anticoagulation. Minor/Significance Unknown.
tolmetin
Minor (1)tolmetin and danshen both increase anticoagulation. Minor/Significance Unknown.

Adverse Effects

Pruritis, reduced appetite, stomach upset

Contraindications

Bleeding disorders

Pregnancy & Lactation

Pregnancy Category: avoid use

Lactation: avoid use

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Pharmacology

Metabolism: N/A

Excretion: N/A

Mechanism of Action

Root has antispasmodic and antithrombotic properties; increases coronary flow rate

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

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Sections Danshen
Suggested Dosing
Suggested Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology

Danshen (Herb/Suppl)