Chitosan (Herb/Suppl)

Brand and Other Names:chitin, chitosan ascorbate, more...deacetylated chitin biopolymer, N,O-sulfated chitosan, N-carboxybutyl chitosan, O-sulfated N-acetylchitosan, sulfated N-carboxymethylchitosan, sulfated O-carboxymethylchitosan
  • Print

Suggested Dosing

Renal Failure with Chronic Hemodialysis

1.35 g PO TID

Topical

Dosage varies

Next:

Suggested Uses

Hypercholesterolemia, periodontitis (topical use), hemodialysis (chronic), weight loss, Crohn's disease

Previous
Next:

Interactions

Interaction Checker

and Chitosan

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            All Interactions Sort By:
             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (12)

                • antithrombin alfa

                  chitosan increases effects of antithrombin alfa by Other (see comment). Use Caution/Monitor. Comment: Chitosan can decrease GI absorption of vitamin K, enhancing anticoagulant effects.

                • antithrombin III

                  chitosan increases effects of antithrombin III by Other (see comment). Use Caution/Monitor. Comment: Chitosan can decrease GI absorption of vitamin K, enhancing anticoagulant effects.

                • argatroban

                  chitosan increases effects of argatroban by Other (see comment). Use Caution/Monitor. Comment: Chitosan can decrease GI absorption of vitamin K, enhancing anticoagulant effects.

                • bemiparin

                  chitosan increases effects of bemiparin by Other (see comment). Use Caution/Monitor. Comment: Chitosan can decrease GI absorption of vitamin K, enhancing anticoagulant effects.

                • bivalirudin

                  chitosan increases effects of bivalirudin by Other (see comment). Use Caution/Monitor. Comment: Chitosan can decrease GI absorption of vitamin K, enhancing anticoagulant effects.

                • dabigatran

                  chitosan increases effects of dabigatran by Other (see comment). Use Caution/Monitor. Comment: Chitosan can decrease GI absorption of vitamin K, enhancing anticoagulant effects.

                • dalteparin

                  chitosan increases effects of dalteparin by Other (see comment). Use Caution/Monitor. Comment: Chitosan can decrease GI absorption of vitamin K, enhancing anticoagulant effects.

                • enoxaparin

                  chitosan increases effects of enoxaparin by Other (see comment). Use Caution/Monitor. Comment: Chitosan can decrease GI absorption of vitamin K, enhancing anticoagulant effects.

                • fondaparinux

                  chitosan increases effects of fondaparinux by Other (see comment). Use Caution/Monitor. Comment: Chitosan can decrease GI absorption of vitamin K, enhancing anticoagulant effects.

                • heparin

                  chitosan increases effects of heparin by Other (see comment). Use Caution/Monitor. Comment: Chitosan can decrease GI absorption of vitamin K, enhancing anticoagulant effects.

                • phenindione

                  chitosan increases effects of phenindione by Other (see comment). Use Caution/Monitor. Comment: Chitosan can decrease GI absorption of vitamin K, enhancing anticoagulant effects.

                • protamine

                  chitosan increases effects of protamine by Other (see comment). Use Caution/Monitor. Comment: Chitosan can decrease GI absorption of vitamin K, enhancing anticoagulant effects.

                Minor (2)

                • vitamin A

                  chitosan decreases levels of vitamin A by inhibition of GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

                • vitamin E

                  chitosan decreases levels of vitamin E by inhibition of GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

                Previous
                Next:

                Adverse Effects

                None reported

                Previous
                Next:

                Warnings

                Contraindications

                None reported

                Cautions

                Shellfish allergy

                Previous
                Next:

                Pregnancy & Lactation

                Pregnancy Category: avoid use

                Lactation: avoid use

                Pregnancy Categories

                A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                NA: Information not available.

                Previous
                Next:

                Pharmacology

                Metabolism: N/A

                Excretion: N/A

                Mechanism of Action

                Crustacean shell derivative; prevents enterohepatic recirculation of cholesterol

                Topical: protects periodontal pockets from oxygen, allowing tissue proliferation

                Previous
                Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.