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      Drugs & Diseases

      Cinnamon (Herb/Suppl)

      Brand and Other Names:Cinnamon Cassia, batavia cassia, more...batavia cinnamon, cassia aromaticum, Ceylon cinnamon, Chinese cinnamon, cinnamomum sp, padang cassia, panang cinnamon, Saigon cassia, Saigon cinnamon
      • Print

      Suggested Dosing

      Diabetes Type 1 & 2

      1-6 grams (1 teaspoon = 4.75 grams) of cassia cinnamon PO qD for up to 4 months

      Dried Bark

      2-6 g/d PO

      Tincture

      3-7 mL PO TID

      Essential Oil

      0.05-0.2 mL/d

      Next:

      Suggested Uses

      Diabetes, GI antispasmodic/antiflatulent, diarrhea, dysmenorrhea

      Cold, influenza, general antimicrobial (essential oil)

      Efficacy

      Placebo-controlled human trial demonstrated decr blood glucose, triglycerides, LDL, total cholesterol in type 2 diabetes (dose-dependent: 6 g/d most effective)

      Possibly effective as antispasmodic

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      Interactions

      Interaction Checker

      and Cinnamon

      No Results

         activity indicator 
        No Interactions Found
        Interactions Found

        Contraindicated

          Serious - Use Alternative

            Significant - Monitor Closely

              Minor

                All Interactions Sort By:
                 activity indicator 

                Contraindicated (0)

                  Serious - Use Alternative (0)

                    Monitor Closely (96)

                    • acarbose

                      cinnamon increases effects of acarbose by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • aceclofenac

                      aceclofenac and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • acemetacin

                      acemetacin and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • agrimony

                      agrimony and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • albiglutide

                      cinnamon increases effects of albiglutide by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • alfalfa

                      alfalfa and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • alteplase

                      alteplase and cinnamon both increase anticoagulation. Use Caution/Monitor. In theory, cinnamon may interact with blood-thinning medications due to the presence of coumarin.

                    • American ginseng

                      American ginseng and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • antithrombin alfa

                      antithrombin alfa and cinnamon both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • antithrombin III

                      antithrombin III and cinnamon both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • argatroban

                      argatroban and cinnamon both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • aspirin

                      aspirin and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • aspirin rectal

                      aspirin rectal and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • aspirin/citric acid/sodium bicarbonate

                      aspirin/citric acid/sodium bicarbonate and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • bemiparin

                      bemiparin and cinnamon both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • bivalirudin

                      bivalirudin and cinnamon both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • celecoxib

                      celecoxib and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • chlorpropamide

                      cinnamon increases effects of chlorpropamide by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • choline magnesium trisalicylate

                      choline magnesium trisalicylate and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • cordyceps

                      cinnamon and cordyceps both increase anticoagulation. Use Caution/Monitor.

                    • dabigatran

                      dabigatran and cinnamon both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • dalteparin

                      dalteparin and cinnamon both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • diclofenac

                      diclofenac and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • diflunisal

                      diflunisal and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • dong quai

                      cinnamon and dong quai both increase anticoagulation. Use Caution/Monitor.

                    • enoxaparin

                      enoxaparin and cinnamon both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • epoprostenol

                      cinnamon and epoprostenol both increase anticoagulation. Use Caution/Monitor.

                    • etodolac

                      etodolac and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • exenatide injectable solution

                      cinnamon increases effects of exenatide injectable solution by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • exenatide injectable suspension

                      cinnamon increases effects of exenatide injectable suspension by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • fennel

                      cinnamon and fennel both increase anticoagulation. Use Caution/Monitor.

                    • fenoprofen

                      fenoprofen and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • feverfew

                      cinnamon and feverfew both increase anticoagulation. Use Caution/Monitor.

                    • flurbiprofen

                      flurbiprofen and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • fondaparinux

                      fondaparinux and cinnamon both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • forskolin

                      cinnamon and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • garlic

                      cinnamon and garlic both increase anticoagulation. Use Caution/Monitor.

                    • ginger

                      cinnamon and ginger both increase anticoagulation. Use Caution/Monitor.

                    • ginkgo biloba

                      cinnamon and ginkgo biloba both increase anticoagulation. Use Caution/Monitor.

                    • glimepiride

                      cinnamon increases effects of glimepiride by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • glipizide

                      cinnamon increases effects of glipizide by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • glyburide

                      cinnamon increases effects of glyburide by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • heparin

                      heparin and cinnamon both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • horse chestnut seed

                      cinnamon and horse chestnut seed both increase anticoagulation. Use Caution/Monitor.

                    • ibuprofen

                      ibuprofen and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • ibuprofen IV

                      ibuprofen IV and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • indomethacin

                      indomethacin and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • insulin aspart

                      cinnamon increases effects of insulin aspart by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • insulin detemir

                      cinnamon increases effects of insulin detemir by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • insulin glargine

                      cinnamon increases effects of insulin glargine by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • insulin glulisine

                      cinnamon increases effects of insulin glulisine by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • insulin lispro

                      cinnamon increases effects of insulin lispro by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • insulin NPH

                      cinnamon increases effects of insulin NPH by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • insulin regular human

                      cinnamon increases effects of insulin regular human by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • ketoprofen

                      ketoprofen and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • ketorolac

                      ketorolac and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • ketorolac intranasal

                      ketorolac intranasal and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • liraglutide

                      cinnamon increases effects of liraglutide by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • lornoxicam

                      lornoxicam and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • meclofenamate

                      meclofenamate and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • mefenamic acid

                      mefenamic acid and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • meloxicam

                      meloxicam and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • metformin

                      cinnamon increases effects of metformin by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • miglitol

                      cinnamon increases effects of miglitol by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • mistletoe

                      cinnamon increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                    • nabumetone

                      nabumetone and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • naproxen

                      naproxen and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • nateglinide

                      cinnamon increases effects of nateglinide by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • nettle

                      cinnamon increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                    • oxaprozin

                      oxaprozin and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • panax ginseng

                      cinnamon and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                    • parecoxib

                      parecoxib and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • pau d'arco

                      cinnamon and pau d'arco both increase anticoagulation. Use Caution/Monitor.

                    • phenindione

                      phenindione and cinnamon both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • phytoestrogens

                      cinnamon and phytoestrogens both increase anticoagulation. Use Caution/Monitor.

                    • pioglitazone

                      cinnamon increases effects of pioglitazone by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • piroxicam

                      piroxicam and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • protamine

                      protamine and cinnamon both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • reishi

                      cinnamon and reishi both increase anticoagulation. Use Caution/Monitor.

                    • repaglinide

                      cinnamon increases effects of repaglinide by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • reteplase

                      reteplase and cinnamon both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • rosiglitazone

                      cinnamon increases effects of rosiglitazone by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • salicylates (non-asa)

                      salicylates (non-asa) and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • salsalate

                      salsalate and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • saxagliptin

                      cinnamon increases effects of saxagliptin by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • Siberian ginseng

                      cinnamon and Siberian ginseng both increase anticoagulation. Use Caution/Monitor.

                    • sitagliptin

                      cinnamon increases effects of sitagliptin by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • sulfasalazine

                      sulfasalazine and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • sulindac

                      sulindac and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • tenecteplase

                      tenecteplase and cinnamon both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • tolazamide

                      cinnamon increases effects of tolazamide by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • tolbutamide

                      cinnamon increases effects of tolbutamide by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    • tolfenamic acid

                      tolfenamic acid and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • tolmetin

                      tolmetin and cinnamon both increase anticoagulation. Use Caution/Monitor.

                    • turmeric

                      cinnamon and turmeric both increase anticoagulation. Use Caution/Monitor.

                    • vildagliptin

                      cinnamon increases effects of vildagliptin by pharmacodynamic synergism. Use Caution/Monitor. Potential for hypoglycemia.

                    Minor (3)

                    • anamu

                      anamu and cinnamon both increase anticoagulation. Minor/Significance Unknown.

                    • danshen

                      cinnamon and danshen both increase anticoagulation. Minor/Significance Unknown.

                    • devil's claw

                      cinnamon and devil's claw both increase anticoagulation. Minor/Significance Unknown.

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                    Adverse Effects

                    Frequency Not Defined

                    Essential oil may irritate mucous membranes

                    Excessive doses may cause hypoglycemia

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                    Warnings

                    Contraindications

                    Hypersensitivity

                    Pregnancy (> amounts found in food)

                    Cautions

                    Most preparations contain cassia cinnamon, a coumarin-containing variety

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                    Pregnancy & Lactation

                    Pregnancy Category: N/A

                    Lactation: N/A

                    Pregnancy Categories

                    A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                    B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                    C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                    D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                    X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                    NA: Information not available.

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                    Pharmacology

                    Metabolism: N/A

                    Excretion: N/A

                    Mechanism of Action

                    Cinnamic Acid - hypoglycemic properties

                    Volatile (essential) oils demonstrate antimicrobial activity in vitro, & decrease smooth muscle spasm

                    Tannins are astringent (anti-hemorrhagic)

                    Previous
                    Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
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