Cipro HC Otic (hydrocortisone-ciprofloxacin) dosing, indications, interactions, adverse effects, and more

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Sections hydrocortisone/ciprofloxacin
Dosing & Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology
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Patient Handout
Formulary

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

ciprofloxacin/hydrocortisone

suspension

0.2%/1%

Acute Otitis Externa

3 gtt in affected ear q12hr for 7 days

Dosage Forms & Strengths

ciprofloxacin/hydrocortisone

suspension

0.2%/1%

Acute Otitis Externa

< 1 year

Safety and efficacy not established

> 1 year

3 gtt in affected ear q12hr for 7 days

Interaction Checker

Enter a drug name and hydrocortisone/ciprofloxacin

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No Interactions Found

Interactions Found

Contraindicated

Serious - Use Alternative

Significant - Monitor Closely

Minor

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Frequency Not Defined

Headache

Pruritus

Migraine headache

Hyperesthesia

Paresthesias

Fungal dermatitis

Cough

Rash

Dermatitis

Urticaria

Alopecia

Contraindications

Hypersensitivity to drugs or components

Tympanic membrane perforation (nonsterile preparation)

Viral infections of external canal including varicella & herpes simplex infections

Cautions

Not for ophthalmic use or injection

Prolonged use may result in bacterial or fungal overgrowth

Resistance to the product may develop

If infection not improved after one week of therapy, cultures should be obtained to guide further treatment

Discontinue at first appearance of skin rash or any other sign of hypersensitivity; serious and occasionally fatal hypersensitivity (anaphylactic) reactions, some following first dose, reported in patients receiving systemic quinolones; serious acute hypersensitivity reactions may require immediate emergency treatment

Dropper cap contains natural rubber (latex) which may cause severe allergic reactions

Pregnancy & Lactation

Pregnancy Category: C

Lactation: Excretion in breast milk unknown; not recommended

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Mechanism of Action

Ciprofloxacin: Fluoroquinolone antibiotic; inhibits DNA gyrase; promotes breakage of double-stranded DNA; bactericidal

Hydrocortisone: Antiinflammatory agent

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Patient Handout

Formulary

FormularyPatient Discounts

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The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

View explanations for tiers and restrictions

Tier	Description
1	This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2	This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC	NOT COVERED – Drugs that are not covered by the plan.

Code	Definition
PA	Prior Authorization Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL	Quantity Limits Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST	Step Therapy Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR	Other Restrictions Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

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Sections hydrocortisone/ciprofloxacin
Dosing & Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology
Images
Patient Handout
Formulary

hydrocortisone/ciprofloxacin (Rx)

Dosing & Uses

Dosage Forms & Strengths

suspension

Acute Otitis Externa

Dosage Forms & Strengths

suspension

Acute Otitis Externa

< 1 year

> 1 year

Interactions

Interaction Checker

Contraindicated

Serious - Use Alternative

Significant - Monitor Closely

Minor

Adverse Effects

Frequency Not Defined

Warnings

Contraindications

Cautions

Pregnancy & Lactation

Pregnancy Categories

Pharmacology

Mechanism of Action

Images

Patient Handout

Formulary

Plans

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