Dosing & Uses
Dosage Forms & Strengths
ciprofloxacin/hydrocortisone
suspension
- 0.2%/1%
Acute Otitis Externa
3 gtt in affected ear q12hr for 7 days
Dosage Forms & Strengths
ciprofloxacin/hydrocortisone
suspension
- 0.2%/1%
Acute Otitis Externa
< 1 year
- Safety and efficacy not established
> 1 year
- 3 gtt in affected ear q12hr for 7 days
Interactions
Interaction Checker
No Results

Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor

Adverse Effects
Frequency Not Defined
Headache
Pruritus
Migraine headache
Hyperesthesia
Paresthesias
Fungal dermatitis
Cough
Rash
Dermatitis
Urticaria
Alopecia
Warnings
Contraindications
Hypersensitivity to drugs or components
Tympanic membrane perforation (nonsterile preparation)
Viral infections of external canal including varicella & herpes simplex infections
Cautions
Not for ophthalmic use or injection
Prolonged use may result in bacterial or fungal overgrowth
Resistance to the product may develop
If infection not improved after one week of therapy, cultures should be obtained to guide further treatment
Discontinue at first appearance of skin rash or any other sign of hypersensitivity; serious and occasionally fatal hypersensitivity (anaphylactic) reactions, some following first dose, reported in patients receiving systemic quinolones; serious acute hypersensitivity reactions may require immediate emergency treatment
Dropper cap contains natural rubber (latex) which may cause severe allergic reactions
Pregnancy & Lactation
Pregnancy Category: C
Lactation: Excretion in breast milk unknown; not recommended
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Ciprofloxacin: Fluoroquinolone antibiotic; inhibits DNA gyrase; promotes breakage of double-stranded DNA; bactericidal
Hydrocortisone: Antiinflammatory agent
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Patient Handout
Formulary
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