Suggested Dosing
Oral
100-300 mg/day PO of extract containing 10-20% forskolin
Inhalation
Asthma: 10 mg of forskolin powder; use a Spinhaler inhalator
Suggested Uses
Cancer, obesity, glaucoma, allergies & asthma; heart failure, intestinal spasms, dysmenorrhea, IBS, UTI, hypertension, angina, insomnia, & convulsions
Efficacy
Small clinical studies indicate obesity reduction potential as well as asthma prevention
Interactions
Interaction Checker
No Results
Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor
Adverse Effects
Hypotension (with beta-blockers, vasodilators, calcium channel blockers), tachycardia, bleeding
Warnings
Contraindications
Data not available
Cautions
Risk of bleeding
Pregnancy & Lactation
Pregnancy Category: avoid use
Lactation: avoid use
Pregnancy Categories
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Pharmacology
Metabolism: N/A
Excretion: N/A
Mechanism of Action
Promotes activation of adenylate cyclase & incr intracellular cAMP resulting in beta-adrenergic effects:
- positive inotrope
- vasodilator
- inhibits Plt aggregation
