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      Drugs & Diseases

      Forskolin (Herb/Suppl)

      Brand and Other Names:coleus forskohlii, colforsin, more...makandi, maohouqiaoruihua, pashanabhedi
      • Print

      Suggested Dosing

      Oral

      100-300 mg/day PO of extract containing 10-20% forskolin

      Inhalation

      Asthma: 10 mg of forskolin powder; use a Spinhaler inhalator

      Next:

      Suggested Uses

      Cancer, obesity, glaucoma, allergies & asthma; heart failure, intestinal spasms, dysmenorrhea, IBS, UTI, hypertension, angina, insomnia, & convulsions

      Efficacy

      Small clinical studies indicate obesity reduction potential as well as asthma prevention

      Previous
      Next:

      Interactions

      Interaction Checker

      and Forskolin

      No Results

         activity indicator 
        No Interactions Found
        Interactions Found

        Contraindicated

          Serious - Use Alternative

            Significant - Monitor Closely

              Minor

                All Interactions Sort By:
                 activity indicator 

                Contraindicated (0)

                  Serious - Use Alternative (0)

                    Monitor Closely (69)

                    • aceclofenac

                      aceclofenac and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • acemetacin

                      acemetacin and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • agrimony

                      agrimony and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • alfalfa

                      alfalfa and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • alteplase

                      alteplase and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely. Forskolin may cause bleeding due to additive platelet inhibition.

                    • American ginseng

                      American ginseng and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • antithrombin alfa

                      antithrombin alfa and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • antithrombin III

                      antithrombin III and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • argatroban

                      argatroban and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • aspirin

                      aspirin and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • aspirin rectal

                      aspirin rectal and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • aspirin/citric acid/sodium bicarbonate

                      aspirin/citric acid/sodium bicarbonate and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • bemiparin

                      bemiparin and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • bivalirudin

                      bivalirudin and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • celecoxib

                      celecoxib and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • choline magnesium trisalicylate

                      choline magnesium trisalicylate and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • cinnamon

                      cinnamon and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • cordyceps

                      cordyceps and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • dabigatran

                      dabigatran and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • dalteparin

                      dalteparin and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • diclofenac

                      diclofenac and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • diflunisal

                      diflunisal and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • dong quai

                      dong quai and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • enoxaparin

                      enoxaparin and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • epoprostenol

                      epoprostenol and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • etodolac

                      etodolac and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • fennel

                      fennel and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • fenoprofen

                      fenoprofen and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • feverfew

                      feverfew and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • flurbiprofen

                      flurbiprofen and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • fondaparinux

                      fondaparinux and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • garlic

                      forskolin and garlic both increase anticoagulation. Use Caution/Monitor.

                    • ginger

                      forskolin and ginger both increase anticoagulation. Use Caution/Monitor.

                    • ginkgo biloba

                      forskolin and ginkgo biloba both increase anticoagulation. Use Caution/Monitor.

                    • heparin

                      heparin and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • horse chestnut seed

                      forskolin and horse chestnut seed both increase anticoagulation. Use Caution/Monitor.

                    • ibuprofen

                      ibuprofen and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • ibuprofen IV

                      ibuprofen IV and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • indomethacin

                      indomethacin and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • ketoprofen

                      ketoprofen and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • ketorolac

                      ketorolac and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • ketorolac intranasal

                      ketorolac intranasal and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • lornoxicam

                      lornoxicam and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • meclofenamate

                      meclofenamate and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • mefenamic acid

                      mefenamic acid and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • meloxicam

                      meloxicam and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • mistletoe

                      forskolin increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                    • nabumetone

                      nabumetone and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • naproxen

                      naproxen and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • nettle

                      forskolin increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                    • oxaprozin

                      oxaprozin and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • panax ginseng

                      forskolin and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                    • parecoxib

                      parecoxib and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • pau d'arco

                      forskolin and pau d'arco both increase anticoagulation. Use Caution/Monitor.

                    • phenindione

                      phenindione and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • phytoestrogens

                      forskolin and phytoestrogens both increase anticoagulation. Use Caution/Monitor.

                    • piroxicam

                      piroxicam and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • protamine

                      protamine and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • reishi

                      forskolin and reishi both increase anticoagulation. Use Caution/Monitor.

                    • reteplase

                      reteplase and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • salicylates (non-asa)

                      salicylates (non-asa) and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • salsalate

                      salsalate and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • Siberian ginseng

                      forskolin and Siberian ginseng both increase anticoagulation. Use Caution/Monitor.

                    • sulfasalazine

                      sulfasalazine and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • sulindac

                      sulindac and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • tenecteplase

                      tenecteplase and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                    • tolfenamic acid

                      tolfenamic acid and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • tolmetin

                      tolmetin and forskolin both increase anticoagulation. Use Caution/Monitor.

                    • vitamin K1 (phytonadione)

                      forskolin increases and vitamin K1 (phytonadione) decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                    Minor (81)

                    • acarbose

                      forskolin increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • acebutolol

                      forskolin increases effects of acebutolol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • amiloride

                      forskolin increases effects of amiloride by pharmacodynamic synergism. Minor/Significance Unknown.

                    • amlodipine

                      forskolin increases effects of amlodipine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • anamu

                      anamu and forskolin both increase anticoagulation. Minor/Significance Unknown.

                    • atenolol

                      forskolin increases effects of atenolol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • bendroflumethiazide

                      forskolin increases effects of bendroflumethiazide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • betaxolol

                      forskolin increases effects of betaxolol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • bisoprolol

                      forskolin increases effects of bisoprolol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • bosentan

                      forskolin increases effects of bosentan by pharmacodynamic synergism. Minor/Significance Unknown.

                    • bumetanide

                      forskolin increases effects of bumetanide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • carvedilol

                      forskolin increases effects of carvedilol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • celiprolol

                      forskolin increases effects of celiprolol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • chlorothiazide

                      forskolin increases effects of chlorothiazide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • chlorpropamide

                      forskolin increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • chlorthalidone

                      forskolin increases effects of chlorthalidone by pharmacodynamic synergism. Minor/Significance Unknown.

                    • clevidipine

                      forskolin increases effects of clevidipine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • clonidine

                      forskolin increases effects of clonidine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • cyclopenthiazide

                      forskolin increases effects of cyclopenthiazide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • danshen

                      danshen and forskolin both increase anticoagulation. Minor/Significance Unknown.

                    • devil's claw

                      devil's claw and forskolin both increase anticoagulation. Minor/Significance Unknown.

                    • diltiazem

                      forskolin increases effects of diltiazem by pharmacodynamic synergism. Minor/Significance Unknown.

                    • drospirenone

                      forskolin increases effects of drospirenone by pharmacodynamic synergism. Minor/Significance Unknown.

                    • eplerenone

                      forskolin increases effects of eplerenone by pharmacodynamic synergism. Minor/Significance Unknown.

                    • epoprostenol

                      forskolin increases effects of epoprostenol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • esmolol

                      forskolin increases effects of esmolol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • ethacrynic acid

                      forskolin increases effects of ethacrynic acid by pharmacodynamic synergism. Minor/Significance Unknown.

                    • felodipine

                      forskolin increases effects of felodipine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • fenoldopam

                      forskolin increases effects of fenoldopam by pharmacodynamic synergism. Minor/Significance Unknown.

                    • furosemide

                      forskolin increases effects of furosemide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • glimepiride

                      forskolin increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • glipizide

                      forskolin increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • glyburide

                      forskolin increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • guanfacine

                      forskolin increases effects of guanfacine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • hydralazine

                      forskolin increases effects of hydralazine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • hydrochlorothiazide

                      forskolin increases effects of hydrochlorothiazide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • iloprost

                      forskolin increases effects of iloprost by pharmacodynamic synergism. Minor/Significance Unknown.

                    • indapamide

                      forskolin increases effects of indapamide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • insulin aspart

                      forskolin increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • insulin detemir

                      forskolin increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • insulin glargine

                      forskolin increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • insulin glulisine

                      forskolin increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • insulin lispro

                      forskolin increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • insulin NPH

                      forskolin increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • insulin regular human

                      forskolin increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • isradipine

                      forskolin increases effects of isradipine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • ketanserin

                      forskolin increases effects of ketanserin by pharmacodynamic synergism. Minor/Significance Unknown.

                    • labetalol

                      forskolin increases effects of labetalol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • mecamylamine

                      forskolin increases effects of mecamylamine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • metformin

                      forskolin increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • methyclothiazide

                      forskolin increases effects of methyclothiazide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • metolazone

                      forskolin increases effects of metolazone by pharmacodynamic synergism. Minor/Significance Unknown.

                    • metoprolol

                      forskolin increases effects of metoprolol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • metyrosine

                      forskolin increases effects of metyrosine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • miglitol

                      forskolin increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • minoxidil

                      forskolin increases effects of minoxidil by pharmacodynamic synergism. Minor/Significance Unknown.

                    • moxonidine

                      forskolin increases effects of moxonidine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • nadolol

                      forskolin increases effects of nadolol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • nateglinide

                      forskolin increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • nebivolol

                      forskolin increases effects of nebivolol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • nicardipine

                      forskolin increases effects of nicardipine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • nifedipine

                      forskolin increases effects of nifedipine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • nisoldipine

                      forskolin increases effects of nisoldipine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • penbutolol

                      forskolin increases effects of penbutolol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • pindolol

                      forskolin increases effects of pindolol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • pioglitazone

                      forskolin increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • propranolol

                      forskolin increases effects of propranolol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • repaglinide

                      forskolin increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • rosiglitazone

                      forskolin increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • saxagliptin

                      forskolin increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • sitagliptin

                      forskolin increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • sotalol

                      forskolin increases effects of sotalol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • spironolactone

                      forskolin increases effects of spironolactone by pharmacodynamic synergism. Minor/Significance Unknown.

                    • timolol

                      forskolin increases effects of timolol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • tolazamide

                      forskolin increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • tolbutamide

                      forskolin increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    • torsemide

                      forskolin increases effects of torsemide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • treprostinil

                      forskolin increases effects of treprostinil by pharmacodynamic synergism. Minor/Significance Unknown.

                    • triamterene

                      forskolin increases effects of triamterene by pharmacodynamic synergism. Minor/Significance Unknown.

                    • verapamil

                      forskolin increases effects of verapamil by pharmacodynamic synergism. Minor/Significance Unknown.

                    • vildagliptin

                      forskolin increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                    Previous
                    Next:

                    Adverse Effects

                    Hypotension (with beta-blockers, vasodilators, calcium channel blockers), tachycardia, bleeding

                    Previous
                    Next:

                    Warnings

                    Contraindications

                    Data not available

                    Cautions

                    Risk of bleeding

                    Previous
                    Next:

                    Pregnancy & Lactation

                    Pregnancy Category: avoid use

                    Lactation: avoid use

                    Pregnancy Categories

                    A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                    B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                    C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                    D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                    X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                    NA: Information not available.

                    Previous
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                    Pharmacology

                    Metabolism: N/A

                    Excretion: N/A

                    Mechanism of Action

                    Promotes activation of adenylate cyclase & incr intracellular cAMP resulting in beta-adrenergic effects:

                    • positive inotrope
                    • vasodilator
                    • inhibits Plt aggregation
                    Previous
                    Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
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