Forskolin (Herb/Suppl)

Brand and Other Names:coleus forskohlii, colforsin, more...makandi, maohouqiaoruihua, pashanabhedi
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Suggested Dosing

Oral

100-300 mg/day PO of extract containing 10-20% forskolin

Inhalation

Asthma: 10 mg of forskolin powder; use a Spinhaler inhalator

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Suggested Uses

Cancer, obesity, glaucoma, allergies & asthma; heart failure, intestinal spasms, dysmenorrhea, IBS, UTI, hypertension, angina, insomnia, & convulsions

Efficacy

Small clinical studies indicate obesity reduction potential as well as asthma prevention

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Interactions

Interaction Checker

and Forskolin

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (69)

                • aceclofenac

                  aceclofenac and forskolin both increase anticoagulation. Use Caution/Monitor.

                • acemetacin

                  acemetacin and forskolin both increase anticoagulation. Use Caution/Monitor.

                • agrimony

                  agrimony and forskolin both increase anticoagulation. Use Caution/Monitor.

                • alfalfa

                  alfalfa and forskolin both increase anticoagulation. Use Caution/Monitor.

                • alteplase

                  alteplase and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely. Forskolin may cause bleeding due to additive platelet inhibition.

                • American ginseng

                  American ginseng and forskolin both increase anticoagulation. Use Caution/Monitor.

                • antithrombin alfa

                  antithrombin alfa and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                • antithrombin III

                  antithrombin III and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                • argatroban

                  argatroban and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                • aspirin

                  aspirin and forskolin both increase anticoagulation. Use Caution/Monitor.

                • aspirin rectal

                  aspirin rectal and forskolin both increase anticoagulation. Use Caution/Monitor.

                • aspirin/citric acid/sodium bicarbonate

                  aspirin/citric acid/sodium bicarbonate and forskolin both increase anticoagulation. Use Caution/Monitor.

                • bemiparin

                  bemiparin and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                • bivalirudin

                  bivalirudin and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                • celecoxib

                  celecoxib and forskolin both increase anticoagulation. Use Caution/Monitor.

                • choline magnesium trisalicylate

                  choline magnesium trisalicylate and forskolin both increase anticoagulation. Use Caution/Monitor.

                • cinnamon

                  cinnamon and forskolin both increase anticoagulation. Use Caution/Monitor.

                • cordyceps

                  cordyceps and forskolin both increase anticoagulation. Use Caution/Monitor.

                • dabigatran

                  dabigatran and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                • dalteparin

                  dalteparin and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                • diclofenac

                  diclofenac and forskolin both increase anticoagulation. Use Caution/Monitor.

                • diflunisal

                  diflunisal and forskolin both increase anticoagulation. Use Caution/Monitor.

                • dong quai

                  dong quai and forskolin both increase anticoagulation. Use Caution/Monitor.

                • enoxaparin

                  enoxaparin and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                • epoprostenol

                  epoprostenol and forskolin both increase anticoagulation. Use Caution/Monitor.

                • etodolac

                  etodolac and forskolin both increase anticoagulation. Use Caution/Monitor.

                • fennel

                  fennel and forskolin both increase anticoagulation. Use Caution/Monitor.

                • fenoprofen

                  fenoprofen and forskolin both increase anticoagulation. Use Caution/Monitor.

                • feverfew

                  feverfew and forskolin both increase anticoagulation. Use Caution/Monitor.

                • flurbiprofen

                  flurbiprofen and forskolin both increase anticoagulation. Use Caution/Monitor.

                • fondaparinux

                  fondaparinux and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                • garlic

                  forskolin and garlic both increase anticoagulation. Use Caution/Monitor.

                • ginger

                  forskolin and ginger both increase anticoagulation. Use Caution/Monitor.

                • ginkgo biloba

                  forskolin and ginkgo biloba both increase anticoagulation. Use Caution/Monitor.

                • heparin

                  heparin and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                • horse chestnut seed

                  forskolin and horse chestnut seed both increase anticoagulation. Use Caution/Monitor.

                • ibuprofen

                  ibuprofen and forskolin both increase anticoagulation. Use Caution/Monitor.

                • ibuprofen IV

                  ibuprofen IV and forskolin both increase anticoagulation. Use Caution/Monitor.

                • indomethacin

                  indomethacin and forskolin both increase anticoagulation. Use Caution/Monitor.

                • ketoprofen

                  ketoprofen and forskolin both increase anticoagulation. Use Caution/Monitor.

                • ketorolac

                  ketorolac and forskolin both increase anticoagulation. Use Caution/Monitor.

                • ketorolac intranasal

                  ketorolac intranasal and forskolin both increase anticoagulation. Use Caution/Monitor.

                • lornoxicam

                  lornoxicam and forskolin both increase anticoagulation. Use Caution/Monitor.

                • meclofenamate

                  meclofenamate and forskolin both increase anticoagulation. Use Caution/Monitor.

                • mefenamic acid

                  mefenamic acid and forskolin both increase anticoagulation. Use Caution/Monitor.

                • meloxicam

                  meloxicam and forskolin both increase anticoagulation. Use Caution/Monitor.

                • mistletoe

                  forskolin increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • nabumetone

                  nabumetone and forskolin both increase anticoagulation. Use Caution/Monitor.

                • naproxen

                  naproxen and forskolin both increase anticoagulation. Use Caution/Monitor.

                • nettle

                  forskolin increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • oxaprozin

                  oxaprozin and forskolin both increase anticoagulation. Use Caution/Monitor.

                • panax ginseng

                  forskolin and panax ginseng both increase anticoagulation. Use Caution/Monitor.

                • parecoxib

                  parecoxib and forskolin both increase anticoagulation. Use Caution/Monitor.

                • pau d'arco

                  forskolin and pau d'arco both increase anticoagulation. Use Caution/Monitor.

                • phenindione

                  phenindione and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                • phytoestrogens

                  forskolin and phytoestrogens both increase anticoagulation. Use Caution/Monitor.

                • piroxicam

                  piroxicam and forskolin both increase anticoagulation. Use Caution/Monitor.

                • protamine

                  protamine and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                • reishi

                  forskolin and reishi both increase anticoagulation. Use Caution/Monitor.

                • reteplase

                  reteplase and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                • salicylates (non-asa)

                  salicylates (non-asa) and forskolin both increase anticoagulation. Use Caution/Monitor.

                • salsalate

                  salsalate and forskolin both increase anticoagulation. Use Caution/Monitor.

                • Siberian ginseng

                  forskolin and Siberian ginseng both increase anticoagulation. Use Caution/Monitor.

                • sulfasalazine

                  sulfasalazine and forskolin both increase anticoagulation. Use Caution/Monitor.

                • sulindac

                  sulindac and forskolin both increase anticoagulation. Use Caution/Monitor.

                • tenecteplase

                  tenecteplase and forskolin both increase anticoagulation. Modify Therapy/Monitor Closely.

                • tolfenamic acid

                  tolfenamic acid and forskolin both increase anticoagulation. Use Caution/Monitor.

                • tolmetin

                  tolmetin and forskolin both increase anticoagulation. Use Caution/Monitor.

                • vitamin K1 (phytonadione)

                  forskolin increases and vitamin K1 (phytonadione) decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                Minor (81)

                • acarbose

                  forskolin increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • acebutolol

                  forskolin increases effects of acebutolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • amiloride

                  forskolin increases effects of amiloride by pharmacodynamic synergism. Minor/Significance Unknown.

                • amlodipine

                  forskolin increases effects of amlodipine by pharmacodynamic synergism. Minor/Significance Unknown.

                • anamu

                  anamu and forskolin both increase anticoagulation. Minor/Significance Unknown.

                • atenolol

                  forskolin increases effects of atenolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • bendroflumethiazide

                  forskolin increases effects of bendroflumethiazide by pharmacodynamic synergism. Minor/Significance Unknown.

                • betaxolol

                  forskolin increases effects of betaxolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • bisoprolol

                  forskolin increases effects of bisoprolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • bosentan

                  forskolin increases effects of bosentan by pharmacodynamic synergism. Minor/Significance Unknown.

                • bumetanide

                  forskolin increases effects of bumetanide by pharmacodynamic synergism. Minor/Significance Unknown.

                • carvedilol

                  forskolin increases effects of carvedilol by pharmacodynamic synergism. Minor/Significance Unknown.

                • celiprolol

                  forskolin increases effects of celiprolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • chlorothiazide

                  forskolin increases effects of chlorothiazide by pharmacodynamic synergism. Minor/Significance Unknown.

                • chlorpropamide

                  forskolin increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • chlorthalidone

                  forskolin increases effects of chlorthalidone by pharmacodynamic synergism. Minor/Significance Unknown.

                • clevidipine

                  forskolin increases effects of clevidipine by pharmacodynamic synergism. Minor/Significance Unknown.

                • clonidine

                  forskolin increases effects of clonidine by pharmacodynamic synergism. Minor/Significance Unknown.

                • cyclopenthiazide

                  forskolin increases effects of cyclopenthiazide by pharmacodynamic synergism. Minor/Significance Unknown.

                • danshen

                  danshen and forskolin both increase anticoagulation. Minor/Significance Unknown.

                • devil's claw

                  devil's claw and forskolin both increase anticoagulation. Minor/Significance Unknown.

                • diltiazem

                  forskolin increases effects of diltiazem by pharmacodynamic synergism. Minor/Significance Unknown.

                • drospirenone

                  forskolin increases effects of drospirenone by pharmacodynamic synergism. Minor/Significance Unknown.

                • eplerenone

                  forskolin increases effects of eplerenone by pharmacodynamic synergism. Minor/Significance Unknown.

                • epoprostenol

                  forskolin increases effects of epoprostenol by pharmacodynamic synergism. Minor/Significance Unknown.

                • esmolol

                  forskolin increases effects of esmolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • ethacrynic acid

                  forskolin increases effects of ethacrynic acid by pharmacodynamic synergism. Minor/Significance Unknown.

                • felodipine

                  forskolin increases effects of felodipine by pharmacodynamic synergism. Minor/Significance Unknown.

                • fenoldopam

                  forskolin increases effects of fenoldopam by pharmacodynamic synergism. Minor/Significance Unknown.

                • furosemide

                  forskolin increases effects of furosemide by pharmacodynamic synergism. Minor/Significance Unknown.

                • glimepiride

                  forskolin increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • glipizide

                  forskolin increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • glyburide

                  forskolin increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • guanfacine

                  forskolin increases effects of guanfacine by pharmacodynamic synergism. Minor/Significance Unknown.

                • hydralazine

                  forskolin increases effects of hydralazine by pharmacodynamic synergism. Minor/Significance Unknown.

                • hydrochlorothiazide

                  forskolin increases effects of hydrochlorothiazide by pharmacodynamic synergism. Minor/Significance Unknown.

                • iloprost

                  forskolin increases effects of iloprost by pharmacodynamic synergism. Minor/Significance Unknown.

                • indapamide

                  forskolin increases effects of indapamide by pharmacodynamic synergism. Minor/Significance Unknown.

                • insulin aspart

                  forskolin increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • insulin detemir

                  forskolin increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • insulin glargine

                  forskolin increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • insulin glulisine

                  forskolin increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • insulin lispro

                  forskolin increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • insulin NPH

                  forskolin increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • insulin regular human

                  forskolin increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • isradipine

                  forskolin increases effects of isradipine by pharmacodynamic synergism. Minor/Significance Unknown.

                • ketanserin

                  forskolin increases effects of ketanserin by pharmacodynamic synergism. Minor/Significance Unknown.

                • labetalol

                  forskolin increases effects of labetalol by pharmacodynamic synergism. Minor/Significance Unknown.

                • mecamylamine

                  forskolin increases effects of mecamylamine by pharmacodynamic synergism. Minor/Significance Unknown.

                • metformin

                  forskolin increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • methyclothiazide

                  forskolin increases effects of methyclothiazide by pharmacodynamic synergism. Minor/Significance Unknown.

                • metolazone

                  forskolin increases effects of metolazone by pharmacodynamic synergism. Minor/Significance Unknown.

                • metoprolol

                  forskolin increases effects of metoprolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • metyrosine

                  forskolin increases effects of metyrosine by pharmacodynamic synergism. Minor/Significance Unknown.

                • miglitol

                  forskolin increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • minoxidil

                  forskolin increases effects of minoxidil by pharmacodynamic synergism. Minor/Significance Unknown.

                • moxonidine

                  forskolin increases effects of moxonidine by pharmacodynamic synergism. Minor/Significance Unknown.

                • nadolol

                  forskolin increases effects of nadolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • nateglinide

                  forskolin increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • nebivolol

                  forskolin increases effects of nebivolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • nicardipine

                  forskolin increases effects of nicardipine by pharmacodynamic synergism. Minor/Significance Unknown.

                • nifedipine

                  forskolin increases effects of nifedipine by pharmacodynamic synergism. Minor/Significance Unknown.

                • nisoldipine

                  forskolin increases effects of nisoldipine by pharmacodynamic synergism. Minor/Significance Unknown.

                • penbutolol

                  forskolin increases effects of penbutolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • pindolol

                  forskolin increases effects of pindolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • pioglitazone

                  forskolin increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • propranolol

                  forskolin increases effects of propranolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • repaglinide

                  forskolin increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • rosiglitazone

                  forskolin increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • saxagliptin

                  forskolin increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • sitagliptin

                  forskolin increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • sotalol

                  forskolin increases effects of sotalol by pharmacodynamic synergism. Minor/Significance Unknown.

                • spironolactone

                  forskolin increases effects of spironolactone by pharmacodynamic synergism. Minor/Significance Unknown.

                • timolol

                  forskolin increases effects of timolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • tolazamide

                  forskolin increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • tolbutamide

                  forskolin increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

                • torsemide

                  forskolin increases effects of torsemide by pharmacodynamic synergism. Minor/Significance Unknown.

                • treprostinil

                  forskolin increases effects of treprostinil by pharmacodynamic synergism. Minor/Significance Unknown.

                • triamterene

                  forskolin increases effects of triamterene by pharmacodynamic synergism. Minor/Significance Unknown.

                • verapamil

                  forskolin increases effects of verapamil by pharmacodynamic synergism. Minor/Significance Unknown.

                • vildagliptin

                  forskolin increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Colenol, a compound found in Coleus root, may stimulate insulin release.

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                Adverse Effects

                Hypotension (with beta-blockers, vasodilators, calcium channel blockers), tachycardia, bleeding

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                Warnings

                Contraindications

                Data not available

                Cautions

                Risk of bleeding

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                Pregnancy & Lactation

                Pregnancy Category: avoid use

                Lactation: avoid use

                Pregnancy Categories

                A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                NA: Information not available.

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                Pharmacology

                Metabolism: N/A

                Excretion: N/A

                Mechanism of Action

                Promotes activation of adenylate cyclase & incr intracellular cAMP resulting in beta-adrenergic effects:

                • positive inotrope
                • vasodilator
                • inhibits Plt aggregation
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                Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.