Forskolin (Herbs/Suppl)

Brand and Other Names:coleus forskohlii, colforsin, more...makandi, maohouqiaoruihua, pashanabhedi
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Suggested Dosing

Oral

100-300 mg/day PO of extract containing 10-20% forskolin

Inhalation

Asthma: 10 mg of forskolin powder; use a Spinhaler inhalator

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Suggested Uses

Cancer, obesity, glaucoma, allergies & asthma; heart failure, intestinal spasms, dysmenorrhea, IBS, UTI, hypertension, angina, insomnia, & convulsions

Efficacy

Small clinical studies indicate obesity reduction potential as well as asthma prevention

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Interactions

Interaction Checker

and Forskolin

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Hypotension (with beta-blockers, vasodilators, calcium channel blockers), tachycardia, bleeding

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            Warnings

            Contraindications

            Data not available

            Cautions

            Risk of bleeding

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            Pregnancy & Lactation

            Pregnancy Category: avoid use

            Lactation: avoid use

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Metabolism: N/A

            Excretion: N/A

            Mechanism of Action

            Promotes activation of adenylate cyclase & incr intracellular cAMP resulting in beta-adrenergic effects:

            • positive inotrope
            • vasodilator
            • inhibits Plt aggregation
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