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      Drugs & Diseases

      Sage (Herb/Suppl)

      Brand and Other Names:common sage, culinary sage, more...garden sage, meadow sage, salvia officinalis, true sage
      • Print

      Suggested Dosing

      Oral

      Tincture: take 1/8 to 1/2 tspn dried sage leaves in a sip of water qDay/BID

      Herbal Tea: drink several cups of sage tea qDay for several weeks

      Gargle or take small sips of sage tea: PRN throughout day

      Alzheimer's Disease

      Salvia Officinalis Hydroalcoholic Extract: equivalent to 1 g sage PO qDay OR

      Salvia Lavandulaefolia Extract: titrated up to 2.5 mg PO TID

      Herpes Labialis

      Topical cream: 23 mg/d of sage extract and rhubartd exract applied q 2-4hr x10-14 days

      Next:

      Suggested Uses

      Treatment of alzheimer's disease and herpes labialis

      Treatement of diarrhea, colds, and excessive perspiration

      GI antispasmodic/antiflatulent, relieves abdominal cramps & bloating

      Antibacterial/antimicrobial

      Treatment for bright red, abundant uterine bleeding & cramps

      May be of benefit for menopausal hot flashes accompanied by profuse perspiration

      Treatment of coughs & tonsil or throat infections

      Stop breast-milk production when weaning a child from breastfeeding

      Hair rinse for dandruff, oily hair, or scalp infections; may restore color to gray or white hair

      Previous
      Next:

      Interactions

      Interaction Checker

      and Sage

      No Results

         activity indicator 
        No Interactions Found
        Interactions Found

        Contraindicated

          Serious - Use Alternative

            Significant - Monitor Closely

              Minor

                All Interactions Sort By:
                 activity indicator 

                Contraindicated (0)

                  Serious - Use Alternative (0)

                    Monitor Closely (1)

                    • topiramate

                      sage and topiramate both increase sedation. Use Caution/Monitor.

                    Minor (204)

                    • acarbose

                      sage increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown.

                    • acetazolamide

                      sage decreases effects of acetazolamide by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • albuterol

                      sage increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • alfentanil

                      alfentanil and sage both increase sedation. Minor/Significance Unknown.

                    • alprazolam

                      alprazolam and sage both increase sedation. Minor/Significance Unknown.

                    • amitriptyline

                      amitriptyline and sage both increase sedation. Minor/Significance Unknown.

                    • amobarbital

                      amobarbital and sage both increase sedation. Minor/Significance Unknown.

                    • amoxapine

                      amoxapine and sage both increase sedation. Minor/Significance Unknown.

                    • apomorphine

                      apomorphine and sage both increase sedation. Minor/Significance Unknown.

                    • arformoterol

                      sage increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • aripiprazole

                      aripiprazole and sage both increase sedation. Minor/Significance Unknown.

                    • armodafinil

                      sage increases and armodafinil decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • azelastine

                      azelastine and sage both increase sedation. Minor/Significance Unknown.

                    • baclofen

                      baclofen and sage both increase sedation. Minor/Significance Unknown.

                    • belladonna and opium

                      belladonna and opium and sage both increase sedation. Minor/Significance Unknown.

                    • benperidol

                      benperidol and sage both increase sedation. Minor/Significance Unknown.

                    • benzphetamine

                      sage increases and benzphetamine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • brompheniramine

                      brompheniramine and sage both increase sedation. Minor/Significance Unknown.

                    • buprenorphine

                      buprenorphine and sage both increase sedation. Minor/Significance Unknown.

                    • buprenorphine buccal

                      buprenorphine buccal and sage both increase sedation. Minor/Significance Unknown.

                    • butabarbital

                      butabarbital and sage both increase sedation. Minor/Significance Unknown.

                    • butalbital

                      butalbital and sage both increase sedation. Minor/Significance Unknown.

                    • butorphanol

                      butorphanol and sage both increase sedation. Minor/Significance Unknown.

                    • caffeine

                      sage increases and caffeine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • calcium/magnesium/potassium/sodium oxybates

                      sage and calcium/magnesium/potassium/sodium oxybates both increase sedation. Minor/Significance Unknown.

                    • carbamazepine

                      sage decreases effects of carbamazepine by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • carbinoxamine

                      carbinoxamine and sage both increase sedation. Minor/Significance Unknown.

                    • carisoprodol

                      carisoprodol and sage both increase sedation. Minor/Significance Unknown.

                    • chloral hydrate

                      chloral hydrate and sage both increase sedation. Minor/Significance Unknown.

                    • chlordiazepoxide

                      chlordiazepoxide and sage both increase sedation. Minor/Significance Unknown.

                    • chlorpheniramine

                      chlorpheniramine and sage both increase sedation. Minor/Significance Unknown.

                    • chlorpromazine

                      chlorpromazine and sage both increase sedation. Minor/Significance Unknown.

                    • chlorpropamide

                      sage increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • chlorzoxazone

                      chlorzoxazone and sage both increase sedation. Minor/Significance Unknown.

                    • cinnarizine

                      cinnarizine and sage both increase sedation. Minor/Significance Unknown.

                    • clemastine

                      clemastine and sage both increase sedation. Minor/Significance Unknown.

                    • clomipramine

                      clomipramine and sage both increase sedation. Minor/Significance Unknown.

                    • clonazepam

                      clonazepam and sage both increase sedation. Minor/Significance Unknown.

                      sage decreases effects of clonazepam by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • clorazepate

                      clorazepate and sage both increase sedation. Minor/Significance Unknown.

                    • clozapine

                      clozapine and sage both increase sedation. Minor/Significance Unknown.

                    • codeine

                      codeine and sage both increase sedation. Minor/Significance Unknown.

                    • cyclizine

                      cyclizine and sage both increase sedation. Minor/Significance Unknown.

                    • cyclobenzaprine

                      cyclobenzaprine and sage both increase sedation. Minor/Significance Unknown.

                    • cyproheptadine

                      cyproheptadine and sage both increase sedation. Minor/Significance Unknown.

                    • dantrolene

                      dantrolene and sage both increase sedation. Minor/Significance Unknown.

                    • desipramine

                      desipramine and sage both increase sedation. Minor/Significance Unknown.

                    • dexchlorpheniramine

                      dexchlorpheniramine and sage both increase sedation. Minor/Significance Unknown.

                    • dexfenfluramine

                      sage increases and dexfenfluramine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • dexmedetomidine

                      dexmedetomidine and sage both increase sedation. Minor/Significance Unknown.

                    • dexmethylphenidate

                      sage increases and dexmethylphenidate decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • dextroamphetamine

                      sage increases and dextroamphetamine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • dextromoramide

                      dextromoramide and sage both increase sedation. Minor/Significance Unknown.

                    • diamorphine

                      diamorphine and sage both increase sedation. Minor/Significance Unknown.

                    • diazepam

                      diazepam and sage both increase sedation. Minor/Significance Unknown.

                      sage decreases effects of diazepam by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • diethylpropion

                      sage increases and diethylpropion decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • difenoxin hcl

                      difenoxin hcl and sage both increase sedation. Minor/Significance Unknown.

                    • dimenhydrinate

                      dimenhydrinate and sage both increase sedation. Minor/Significance Unknown.

                    • diphenhydramine

                      diphenhydramine and sage both increase sedation. Minor/Significance Unknown.

                    • diphenoxylate hcl

                      diphenoxylate hcl and sage both increase sedation. Minor/Significance Unknown.

                    • dipipanone

                      dipipanone and sage both increase sedation. Minor/Significance Unknown.

                    • dobutamine

                      sage increases and dobutamine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • dopamine

                      sage increases and dopamine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • dopexamine

                      sage increases and dopexamine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • doxepin

                      doxepin and sage both increase sedation. Minor/Significance Unknown.

                    • doxylamine

                      doxylamine and sage both increase sedation. Minor/Significance Unknown.

                    • droperidol

                      droperidol and sage both increase sedation. Minor/Significance Unknown.

                    • ephedrine

                      sage increases and ephedrine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • epinephrine

                      sage increases and epinephrine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • epinephrine racemic

                      sage increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • estazolam

                      estazolam and sage both increase sedation. Minor/Significance Unknown.

                    • ethanol

                      ethanol and sage both increase sedation. Minor/Significance Unknown.

                    • ethosuximide

                      sage decreases effects of ethosuximide by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • etomidate

                      etomidate and sage both increase sedation. Minor/Significance Unknown.

                    • eucalyptus

                      eucalyptus and sage both increase sedation. Minor/Significance Unknown.

                    • felbamate

                      sage decreases effects of felbamate by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • fenfluramine

                      sage increases and fenfluramine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • fluphenazine

                      fluphenazine and sage both increase sedation. Minor/Significance Unknown.

                    • flurazepam

                      flurazepam and sage both increase sedation. Minor/Significance Unknown.

                    • formoterol

                      sage increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • fosphenytoin

                      sage decreases effects of fosphenytoin by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • gabapentin

                      sage decreases effects of gabapentin by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • gabapentin enacarbil

                      sage decreases effects of gabapentin enacarbil by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • glimepiride

                      sage increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown.

                    • glipizide

                      sage increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • glyburide

                      sage increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • haloperidol

                      haloperidol and sage both increase sedation. Minor/Significance Unknown.

                    • hydromorphone

                      hydromorphone and sage both increase sedation. Minor/Significance Unknown.

                    • hydroxyzine

                      hydroxyzine and sage both increase sedation. Minor/Significance Unknown.

                    • iloperidone

                      iloperidone and sage both increase sedation. Minor/Significance Unknown.

                    • imipramine

                      imipramine and sage both increase sedation. Minor/Significance Unknown.

                    • insulin aspart

                      sage increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown.

                    • insulin detemir

                      sage increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown.

                    • insulin glargine

                      sage increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • insulin glulisine

                      sage increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown.

                    • insulin lispro

                      sage increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown.

                    • insulin NPH

                      sage increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown.

                    • insulin regular human

                      sage increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown.

                    • isoproterenol

                      sage increases and isoproterenol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • ketotifen, ophthalmic

                      ketotifen, ophthalmic and sage both increase sedation. Minor/Significance Unknown.

                    • lacosamide

                      sage decreases effects of lacosamide by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • lamotrigine

                      sage decreases effects of lamotrigine by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • levalbuterol

                      sage increases and levalbuterol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • levetiracetam

                      sage decreases effects of levetiracetam by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • levorphanol

                      levorphanol and sage both increase sedation. Minor/Significance Unknown.

                    • lisdexamfetamine

                      sage increases and lisdexamfetamine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • lofepramine

                      lofepramine and sage both increase sedation. Minor/Significance Unknown.

                    • lofexidine

                      lofexidine and sage both increase sedation. Minor/Significance Unknown.

                    • loprazolam

                      loprazolam and sage both increase sedation. Minor/Significance Unknown.

                    • lorazepam

                      lorazepam and sage both increase sedation. Minor/Significance Unknown.

                      sage decreases effects of lorazepam by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • lormetazepam

                      lormetazepam and sage both increase sedation. Minor/Significance Unknown.

                    • loxapine

                      loxapine and sage both increase sedation. Minor/Significance Unknown.

                    • loxapine inhaled

                      loxapine inhaled and sage both increase sedation. Minor/Significance Unknown.

                    • maprotiline

                      maprotiline and sage both increase sedation. Minor/Significance Unknown.

                    • marijuana

                      marijuana and sage both increase sedation. Minor/Significance Unknown.

                    • melatonin

                      melatonin and sage both increase sedation. Minor/Significance Unknown.

                    • meperidine

                      meperidine and sage both increase sedation. Minor/Significance Unknown.

                    • meprobamate

                      meprobamate and sage both increase sedation. Minor/Significance Unknown.

                    • metaproterenol

                      sage increases and metaproterenol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • metaxalone

                      metaxalone and sage both increase sedation. Minor/Significance Unknown.

                    • metformin

                      sage increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown.

                    • methadone

                      methadone and sage both increase sedation. Minor/Significance Unknown.

                    • methamphetamine

                      sage increases and methamphetamine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • methocarbamol

                      methocarbamol and sage both increase sedation. Minor/Significance Unknown.

                    • methsuximide

                      sage decreases effects of methsuximide by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • methylenedioxymethamphetamine

                      sage increases and methylenedioxymethamphetamine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • midazolam

                      midazolam and sage both increase sedation. Minor/Significance Unknown.

                    • midodrine

                      sage increases and midodrine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • miglitol

                      sage increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown.

                    • mirtazapine

                      mirtazapine and sage both increase sedation. Minor/Significance Unknown.

                    • modafinil

                      sage increases and modafinil decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • morphine

                      morphine and sage both increase sedation. Minor/Significance Unknown.

                    • motherwort

                      motherwort and sage both increase sedation. Minor/Significance Unknown.

                    • moxonidine

                      moxonidine and sage both increase sedation. Minor/Significance Unknown.

                    • nabilone

                      nabilone and sage both increase sedation. Minor/Significance Unknown.

                    • nalbuphine

                      nalbuphine and sage both increase sedation. Minor/Significance Unknown.

                    • nateglinide

                      sage increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • norepinephrine

                      sage increases and norepinephrine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • nortriptyline

                      nortriptyline and sage both increase sedation. Minor/Significance Unknown.

                    • olanzapine

                      olanzapine and sage both increase sedation. Minor/Significance Unknown.

                    • opium tincture

                      opium tincture and sage both increase sedation. Minor/Significance Unknown.

                    • orphenadrine

                      orphenadrine and sage both increase sedation. Minor/Significance Unknown.

                    • oxazepam

                      oxazepam and sage both increase sedation. Minor/Significance Unknown.

                    • oxcarbazepine

                      sage decreases effects of oxcarbazepine by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • oxycodone

                      oxycodone and sage both increase sedation. Minor/Significance Unknown.

                    • oxymorphone

                      oxymorphone and sage both increase sedation. Minor/Significance Unknown.

                    • paliperidone

                      paliperidone and sage both increase sedation. Minor/Significance Unknown.

                    • papaveretum

                      papaveretum and sage both increase sedation. Minor/Significance Unknown.

                    • papaverine

                      papaverine and sage both increase sedation. Minor/Significance Unknown.

                    • pentazocine

                      pentazocine and sage both increase sedation. Minor/Significance Unknown.

                    • pentobarbital

                      pentobarbital and sage both increase sedation. Minor/Significance Unknown.

                    • perphenazine

                      perphenazine and sage both increase sedation. Minor/Significance Unknown.

                    • phendimetrazine

                      sage increases and phendimetrazine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • phenobarbital

                      phenobarbital and sage both increase sedation. Minor/Significance Unknown.

                      sage decreases effects of phenobarbital by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • phentermine

                      sage increases and phentermine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • phenylephrine

                      sage increases and phenylephrine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • phenylephrine PO

                      sage increases and phenylephrine PO decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown. .

                    • phenytoin

                      sage decreases effects of phenytoin by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • pholcodine

                      pholcodine and sage both increase sedation. Minor/Significance Unknown.

                    • pimozide

                      pimozide and sage both increase sedation. Minor/Significance Unknown.

                    • pioglitazone

                      sage increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown.

                    • pirbuterol

                      sage increases and pirbuterol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • primidone

                      primidone and sage both increase sedation. Minor/Significance Unknown.

                      sage decreases effects of primidone by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • prochlorperazine

                      prochlorperazine and sage both increase sedation. Minor/Significance Unknown.

                    • promethazine

                      promethazine and sage both increase sedation. Minor/Significance Unknown.

                    • propylhexedrine

                      sage increases and propylhexedrine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • protriptyline

                      protriptyline and sage both increase sedation. Minor/Significance Unknown.

                    • quazepam

                      quazepam and sage both increase sedation. Minor/Significance Unknown.

                    • quetiapine

                      quetiapine and sage both increase sedation. Minor/Significance Unknown.

                    • ramelteon

                      ramelteon and sage both increase sedation. Minor/Significance Unknown.

                    • repaglinide

                      sage increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • risperidone

                      risperidone and sage both increase sedation. Minor/Significance Unknown.

                    • rosiglitazone

                      sage increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown.

                    • rufinamide

                      sage decreases effects of rufinamide by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • salmeterol

                      sage increases and salmeterol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • saxagliptin

                      sage increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown.

                    • scullcap

                      sage and scullcap both increase sedation. Minor/Significance Unknown.

                    • secobarbital

                      secobarbital and sage both increase sedation. Minor/Significance Unknown.

                    • shepherd's purse

                      sage and shepherd's purse both increase sedation. Minor/Significance Unknown.

                    • sitagliptin

                      sage increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown.

                    • sodium oxybate

                      sage and sodium oxybate both increase sedation. Minor/Significance Unknown.

                    • sufentanil

                      sufentanil and sage both increase sedation. Minor/Significance Unknown.

                    • tapentadol

                      tapentadol and sage both increase sedation. Minor/Significance Unknown.

                    • temazepam

                      temazepam and sage both increase sedation. Minor/Significance Unknown.

                    • terbutaline

                      sage increases and terbutaline decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • thioridazine

                      thioridazine and sage both increase sedation. Minor/Significance Unknown.

                    • thiothixene

                      thiothixene and sage both increase sedation. Minor/Significance Unknown.

                    • tiagabine

                      sage decreases effects of tiagabine by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • tolazamide

                      sage increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • tolbutamide

                      sage increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown.

                    • topiramate

                      sage decreases effects of topiramate by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • tramadol

                      tramadol and sage both increase sedation. Minor/Significance Unknown.

                    • trazodone

                      trazodone and sage both increase sedation. Minor/Significance Unknown.

                    • triazolam

                      triazolam and sage both increase sedation. Minor/Significance Unknown.

                    • triclofos

                      triclofos and sage both increase sedation. Minor/Significance Unknown.

                    • trifluoperazine

                      trifluoperazine and sage both increase sedation. Minor/Significance Unknown.

                    • trimipramine

                      trimipramine and sage both increase sedation. Minor/Significance Unknown.

                    • triprolidine

                      triprolidine and sage both increase sedation. Minor/Significance Unknown.

                    • valproic acid

                      sage decreases effects of valproic acid by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    • vildagliptin

                      sage increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown.

                    • xylometazoline

                      sage increases and xylometazoline decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • yohimbine

                      sage increases and yohimbine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                    • ziconotide

                      sage and ziconotide both increase sedation. Minor/Significance Unknown.

                    • ziprasidone

                      ziprasidone and sage both increase sedation. Minor/Significance Unknown.

                    • zonisamide

                      sage decreases effects of zonisamide by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                    Previous
                    Next:

                    Adverse Effects

                    Headaches & irritability can occur when consuming excessive amounts of sage

                    Previous
                    Next:

                    Warnings

                    Contraindications

                    Hx of seizures

                    Epilepsy

                    Pregnancy (>amounts found in food)

                    Previous
                    Next:

                    Pregnancy & Lactation

                    Pregnancy Category: N/A

                    Lactation: N/A

                    Pregnancy Categories

                    A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                    B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                    C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                    D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                    X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                    NA: Information not available.

                    Previous
                    Next:

                    Pharmacology

                    Metabolism: N/A

                    Excretion: N/A

                    Mechanism of Action

                    Beta-thujone, a volatile oil occurs in significant amounts in sage

                    Previous
                    Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
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