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    Drugs & Diseases

    Sage (Herb/Suppl)

    Brand and Other Names:common sage, culinary sage, more...garden sage, meadow sage, salvia officinalis, true sage
    • Print

    Suggested Dosing

    Oral

    Tincture: take 1/8 to 1/2 tspn dried sage leaves in a sip of water qDay/BID

    Herbal Tea: drink several cups of sage tea qDay for several weeks

    Gargle or take small sips of sage tea: PRN throughout day

    Alzheimer's Disease

    Salvia Officinalis Hydroalcoholic Extract: equivalent to 1 g sage PO qDay OR

    Salvia Lavandulaefolia Extract: titrated up to 2.5 mg PO TID

    Herpes Labialis

    Topical cream: 23 mg/d of sage extract and rhubartd exract applied q 2-4hr x10-14 days

    Next:

    Suggested Uses

    Treatment of alzheimer's disease and herpes labialis

    Treatement of diarrhea, colds, and excessive perspiration

    GI antispasmodic/antiflatulent, relieves abdominal cramps & bloating

    Antibacterial/antimicrobial

    Treatment for bright red, abundant uterine bleeding & cramps

    May be of benefit for menopausal hot flashes accompanied by profuse perspiration

    Treatment of coughs & tonsil or throat infections

    Stop breast-milk production when weaning a child from breastfeeding

    Hair rinse for dandruff, oily hair, or scalp infections; may restore color to gray or white hair

    Previous
    Next:

    Interactions

    Interaction Checker

    and Sage

    No Results

       activity indicator 
      No Interactions Found
      Interactions Found

      Contraindicated

        Serious - Use Alternative

          Significant - Monitor Closely

            Minor

              All Interactions Sort By:
               activity indicator 

              Contraindicated (0)

                Serious - Use Alternative (0)

                  Monitor Closely (1)

                  • topiramate

                    sage and topiramate both increase sedation. Use Caution/Monitor.

                  Minor (204)

                  • acarbose

                    sage increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown.

                  • acetazolamide

                    sage decreases effects of acetazolamide by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • albuterol

                    sage increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • alfentanil

                    alfentanil and sage both increase sedation. Minor/Significance Unknown.

                  • alprazolam

                    alprazolam and sage both increase sedation. Minor/Significance Unknown.

                  • amitriptyline

                    amitriptyline and sage both increase sedation. Minor/Significance Unknown.

                  • amobarbital

                    amobarbital and sage both increase sedation. Minor/Significance Unknown.

                  • amoxapine

                    amoxapine and sage both increase sedation. Minor/Significance Unknown.

                  • apomorphine

                    apomorphine and sage both increase sedation. Minor/Significance Unknown.

                  • arformoterol

                    sage increases and arformoterol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • aripiprazole

                    aripiprazole and sage both increase sedation. Minor/Significance Unknown.

                  • armodafinil

                    sage increases and armodafinil decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • azelastine

                    azelastine and sage both increase sedation. Minor/Significance Unknown.

                  • baclofen

                    baclofen and sage both increase sedation. Minor/Significance Unknown.

                  • belladonna and opium

                    belladonna and opium and sage both increase sedation. Minor/Significance Unknown.

                  • benperidol

                    benperidol and sage both increase sedation. Minor/Significance Unknown.

                  • benzphetamine

                    sage increases and benzphetamine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • brompheniramine

                    brompheniramine and sage both increase sedation. Minor/Significance Unknown.

                  • buprenorphine

                    buprenorphine and sage both increase sedation. Minor/Significance Unknown.

                  • buprenorphine buccal

                    buprenorphine buccal and sage both increase sedation. Minor/Significance Unknown.

                  • butabarbital

                    butabarbital and sage both increase sedation. Minor/Significance Unknown.

                  • butalbital

                    butalbital and sage both increase sedation. Minor/Significance Unknown.

                  • butorphanol

                    butorphanol and sage both increase sedation. Minor/Significance Unknown.

                  • caffeine

                    sage increases and caffeine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • calcium/magnesium/potassium/sodium oxybates

                    sage and calcium/magnesium/potassium/sodium oxybates both increase sedation. Minor/Significance Unknown.

                  • carbamazepine

                    sage decreases effects of carbamazepine by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • carbinoxamine

                    carbinoxamine and sage both increase sedation. Minor/Significance Unknown.

                  • carisoprodol

                    carisoprodol and sage both increase sedation. Minor/Significance Unknown.

                  • chloral hydrate

                    chloral hydrate and sage both increase sedation. Minor/Significance Unknown.

                  • chlordiazepoxide

                    chlordiazepoxide and sage both increase sedation. Minor/Significance Unknown.

                  • chlorpheniramine

                    chlorpheniramine and sage both increase sedation. Minor/Significance Unknown.

                  • chlorpromazine

                    chlorpromazine and sage both increase sedation. Minor/Significance Unknown.

                  • chlorpropamide

                    sage increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • chlorzoxazone

                    chlorzoxazone and sage both increase sedation. Minor/Significance Unknown.

                  • cinnarizine

                    cinnarizine and sage both increase sedation. Minor/Significance Unknown.

                  • clemastine

                    clemastine and sage both increase sedation. Minor/Significance Unknown.

                  • clomipramine

                    clomipramine and sage both increase sedation. Minor/Significance Unknown.

                  • clonazepam

                    clonazepam and sage both increase sedation. Minor/Significance Unknown.

                    sage decreases effects of clonazepam by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • clorazepate

                    clorazepate and sage both increase sedation. Minor/Significance Unknown.

                  • clozapine

                    clozapine and sage both increase sedation. Minor/Significance Unknown.

                  • codeine

                    codeine and sage both increase sedation. Minor/Significance Unknown.

                  • cyclizine

                    cyclizine and sage both increase sedation. Minor/Significance Unknown.

                  • cyclobenzaprine

                    cyclobenzaprine and sage both increase sedation. Minor/Significance Unknown.

                  • cyproheptadine

                    cyproheptadine and sage both increase sedation. Minor/Significance Unknown.

                  • dantrolene

                    dantrolene and sage both increase sedation. Minor/Significance Unknown.

                  • desipramine

                    desipramine and sage both increase sedation. Minor/Significance Unknown.

                  • dexchlorpheniramine

                    dexchlorpheniramine and sage both increase sedation. Minor/Significance Unknown.

                  • dexfenfluramine

                    sage increases and dexfenfluramine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • dexmedetomidine

                    dexmedetomidine and sage both increase sedation. Minor/Significance Unknown.

                  • dexmethylphenidate

                    sage increases and dexmethylphenidate decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • dextroamphetamine

                    sage increases and dextroamphetamine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • dextromoramide

                    dextromoramide and sage both increase sedation. Minor/Significance Unknown.

                  • diamorphine

                    diamorphine and sage both increase sedation. Minor/Significance Unknown.

                  • diazepam

                    diazepam and sage both increase sedation. Minor/Significance Unknown.

                    sage decreases effects of diazepam by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • diethylpropion

                    sage increases and diethylpropion decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • difenoxin hcl

                    difenoxin hcl and sage both increase sedation. Minor/Significance Unknown.

                  • dimenhydrinate

                    dimenhydrinate and sage both increase sedation. Minor/Significance Unknown.

                  • diphenhydramine

                    diphenhydramine and sage both increase sedation. Minor/Significance Unknown.

                  • diphenoxylate hcl

                    diphenoxylate hcl and sage both increase sedation. Minor/Significance Unknown.

                  • dipipanone

                    dipipanone and sage both increase sedation. Minor/Significance Unknown.

                  • dobutamine

                    sage increases and dobutamine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • dopamine

                    sage increases and dopamine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • dopexamine

                    sage increases and dopexamine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • doxepin

                    doxepin and sage both increase sedation. Minor/Significance Unknown.

                  • doxylamine

                    doxylamine and sage both increase sedation. Minor/Significance Unknown.

                  • droperidol

                    droperidol and sage both increase sedation. Minor/Significance Unknown.

                  • ephedrine

                    sage increases and ephedrine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • epinephrine

                    sage increases and epinephrine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • epinephrine racemic

                    sage increases and epinephrine racemic decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • estazolam

                    estazolam and sage both increase sedation. Minor/Significance Unknown.

                  • ethanol

                    ethanol and sage both increase sedation. Minor/Significance Unknown.

                  • ethosuximide

                    sage decreases effects of ethosuximide by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • etomidate

                    etomidate and sage both increase sedation. Minor/Significance Unknown.

                  • eucalyptus

                    eucalyptus and sage both increase sedation. Minor/Significance Unknown.

                  • felbamate

                    sage decreases effects of felbamate by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • fenfluramine

                    sage increases and fenfluramine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • fluphenazine

                    fluphenazine and sage both increase sedation. Minor/Significance Unknown.

                  • flurazepam

                    flurazepam and sage both increase sedation. Minor/Significance Unknown.

                  • formoterol

                    sage increases and formoterol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • fosphenytoin

                    sage decreases effects of fosphenytoin by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • gabapentin

                    sage decreases effects of gabapentin by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • gabapentin enacarbil

                    sage decreases effects of gabapentin enacarbil by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • glimepiride

                    sage increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown.

                  • glipizide

                    sage increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • glyburide

                    sage increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • haloperidol

                    haloperidol and sage both increase sedation. Minor/Significance Unknown.

                  • hydromorphone

                    hydromorphone and sage both increase sedation. Minor/Significance Unknown.

                  • hydroxyzine

                    hydroxyzine and sage both increase sedation. Minor/Significance Unknown.

                  • iloperidone

                    iloperidone and sage both increase sedation. Minor/Significance Unknown.

                  • imipramine

                    imipramine and sage both increase sedation. Minor/Significance Unknown.

                  • insulin aspart

                    sage increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown.

                  • insulin detemir

                    sage increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown.

                  • insulin glargine

                    sage increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown.

                  • insulin glulisine

                    sage increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown.

                  • insulin lispro

                    sage increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown.

                  • insulin NPH

                    sage increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown.

                  • insulin regular human

                    sage increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown.

                  • isoproterenol

                    sage increases and isoproterenol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • ketotifen, ophthalmic

                    ketotifen, ophthalmic and sage both increase sedation. Minor/Significance Unknown.

                  • lacosamide

                    sage decreases effects of lacosamide by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • lamotrigine

                    sage decreases effects of lamotrigine by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • levalbuterol

                    sage increases and levalbuterol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • levetiracetam

                    sage decreases effects of levetiracetam by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • levorphanol

                    levorphanol and sage both increase sedation. Minor/Significance Unknown.

                  • lisdexamfetamine

                    sage increases and lisdexamfetamine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • lofepramine

                    lofepramine and sage both increase sedation. Minor/Significance Unknown.

                  • lofexidine

                    lofexidine and sage both increase sedation. Minor/Significance Unknown.

                  • loprazolam

                    loprazolam and sage both increase sedation. Minor/Significance Unknown.

                  • lorazepam

                    lorazepam and sage both increase sedation. Minor/Significance Unknown.

                    sage decreases effects of lorazepam by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • lormetazepam

                    lormetazepam and sage both increase sedation. Minor/Significance Unknown.

                  • loxapine

                    loxapine and sage both increase sedation. Minor/Significance Unknown.

                  • loxapine inhaled

                    loxapine inhaled and sage both increase sedation. Minor/Significance Unknown.

                  • maprotiline

                    maprotiline and sage both increase sedation. Minor/Significance Unknown.

                  • marijuana

                    marijuana and sage both increase sedation. Minor/Significance Unknown.

                  • melatonin

                    melatonin and sage both increase sedation. Minor/Significance Unknown.

                  • meperidine

                    meperidine and sage both increase sedation. Minor/Significance Unknown.

                  • meprobamate

                    meprobamate and sage both increase sedation. Minor/Significance Unknown.

                  • metaproterenol

                    sage increases and metaproterenol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • metaxalone

                    metaxalone and sage both increase sedation. Minor/Significance Unknown.

                  • metformin

                    sage increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown.

                  • methadone

                    methadone and sage both increase sedation. Minor/Significance Unknown.

                  • methamphetamine

                    sage increases and methamphetamine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • methocarbamol

                    methocarbamol and sage both increase sedation. Minor/Significance Unknown.

                  • methsuximide

                    sage decreases effects of methsuximide by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • methylenedioxymethamphetamine

                    sage increases and methylenedioxymethamphetamine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • midazolam

                    midazolam and sage both increase sedation. Minor/Significance Unknown.

                  • midodrine

                    sage increases and midodrine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • miglitol

                    sage increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • mirtazapine

                    mirtazapine and sage both increase sedation. Minor/Significance Unknown.

                  • modafinil

                    sage increases and modafinil decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • morphine

                    morphine and sage both increase sedation. Minor/Significance Unknown.

                  • motherwort

                    motherwort and sage both increase sedation. Minor/Significance Unknown.

                  • moxonidine

                    moxonidine and sage both increase sedation. Minor/Significance Unknown.

                  • nabilone

                    nabilone and sage both increase sedation. Minor/Significance Unknown.

                  • nalbuphine

                    nalbuphine and sage both increase sedation. Minor/Significance Unknown.

                  • nateglinide

                    sage increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • norepinephrine

                    sage increases and norepinephrine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • nortriptyline

                    nortriptyline and sage both increase sedation. Minor/Significance Unknown.

                  • olanzapine

                    olanzapine and sage both increase sedation. Minor/Significance Unknown.

                  • opium tincture

                    opium tincture and sage both increase sedation. Minor/Significance Unknown.

                  • orphenadrine

                    orphenadrine and sage both increase sedation. Minor/Significance Unknown.

                  • oxazepam

                    oxazepam and sage both increase sedation. Minor/Significance Unknown.

                  • oxcarbazepine

                    sage decreases effects of oxcarbazepine by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • oxycodone

                    oxycodone and sage both increase sedation. Minor/Significance Unknown.

                  • oxymorphone

                    oxymorphone and sage both increase sedation. Minor/Significance Unknown.

                  • paliperidone

                    paliperidone and sage both increase sedation. Minor/Significance Unknown.

                  • papaveretum

                    papaveretum and sage both increase sedation. Minor/Significance Unknown.

                  • papaverine

                    papaverine and sage both increase sedation. Minor/Significance Unknown.

                  • pentazocine

                    pentazocine and sage both increase sedation. Minor/Significance Unknown.

                  • pentobarbital

                    pentobarbital and sage both increase sedation. Minor/Significance Unknown.

                  • perphenazine

                    perphenazine and sage both increase sedation. Minor/Significance Unknown.

                  • phendimetrazine

                    sage increases and phendimetrazine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • phenobarbital

                    phenobarbital and sage both increase sedation. Minor/Significance Unknown.

                    sage decreases effects of phenobarbital by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • phentermine

                    sage increases and phentermine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • phenylephrine

                    sage increases and phenylephrine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • phenylephrine PO

                    sage increases and phenylephrine PO decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown. .

                  • phenytoin

                    sage decreases effects of phenytoin by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • pholcodine

                    pholcodine and sage both increase sedation. Minor/Significance Unknown.

                  • pimozide

                    pimozide and sage both increase sedation. Minor/Significance Unknown.

                  • pioglitazone

                    sage increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown.

                  • pirbuterol

                    sage increases and pirbuterol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • primidone

                    primidone and sage both increase sedation. Minor/Significance Unknown.

                    sage decreases effects of primidone by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • prochlorperazine

                    prochlorperazine and sage both increase sedation. Minor/Significance Unknown.

                  • promethazine

                    promethazine and sage both increase sedation. Minor/Significance Unknown.

                  • propylhexedrine

                    sage increases and propylhexedrine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • protriptyline

                    protriptyline and sage both increase sedation. Minor/Significance Unknown.

                  • quazepam

                    quazepam and sage both increase sedation. Minor/Significance Unknown.

                  • quetiapine

                    quetiapine and sage both increase sedation. Minor/Significance Unknown.

                  • ramelteon

                    ramelteon and sage both increase sedation. Minor/Significance Unknown.

                  • repaglinide

                    sage increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • risperidone

                    risperidone and sage both increase sedation. Minor/Significance Unknown.

                  • rosiglitazone

                    sage increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown.

                  • rufinamide

                    sage decreases effects of rufinamide by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • salmeterol

                    sage increases and salmeterol decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • saxagliptin

                    sage increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown.

                  • scullcap

                    sage and scullcap both increase sedation. Minor/Significance Unknown.

                  • secobarbital

                    secobarbital and sage both increase sedation. Minor/Significance Unknown.

                  • shepherd's purse

                    sage and shepherd's purse both increase sedation. Minor/Significance Unknown.

                  • sitagliptin

                    sage increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown.

                  • sodium oxybate

                    sage and sodium oxybate both increase sedation. Minor/Significance Unknown.

                  • sufentanil

                    sufentanil and sage both increase sedation. Minor/Significance Unknown.

                  • tapentadol

                    tapentadol and sage both increase sedation. Minor/Significance Unknown.

                  • temazepam

                    temazepam and sage both increase sedation. Minor/Significance Unknown.

                  • terbutaline

                    sage increases and terbutaline decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • thioridazine

                    thioridazine and sage both increase sedation. Minor/Significance Unknown.

                  • thiothixene

                    thiothixene and sage both increase sedation. Minor/Significance Unknown.

                  • tiagabine

                    sage decreases effects of tiagabine by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • tolazamide

                    sage increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • tolbutamide

                    sage increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • topiramate

                    sage decreases effects of topiramate by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • tramadol

                    tramadol and sage both increase sedation. Minor/Significance Unknown.

                  • trazodone

                    trazodone and sage both increase sedation. Minor/Significance Unknown.

                  • triazolam

                    triazolam and sage both increase sedation. Minor/Significance Unknown.

                  • triclofos

                    triclofos and sage both increase sedation. Minor/Significance Unknown.

                  • trifluoperazine

                    trifluoperazine and sage both increase sedation. Minor/Significance Unknown.

                  • trimipramine

                    trimipramine and sage both increase sedation. Minor/Significance Unknown.

                  • triprolidine

                    triprolidine and sage both increase sedation. Minor/Significance Unknown.

                  • valproic acid

                    sage decreases effects of valproic acid by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

                  • vildagliptin

                    sage increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown.

                  • xylometazoline

                    sage increases and xylometazoline decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • yohimbine

                    sage increases and yohimbine decreases sedation. Effect of interaction is not clear, use caution. Minor/Significance Unknown.

                  • ziconotide

                    sage and ziconotide both increase sedation. Minor/Significance Unknown.

                  • ziprasidone

                    ziprasidone and sage both increase sedation. Minor/Significance Unknown.

                  • zonisamide

                    sage decreases effects of zonisamide by pharmacodynamic antagonism. Minor/Significance Unknown. Theoretical interaction; some species of sage may cause convulsions.

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                  Next:

                  Adverse Effects

                  Headaches & irritability can occur when consuming excessive amounts of sage

                  Previous
                  Next:

                  Warnings

                  Contraindications

                  Hx of seizures

                  Epilepsy

                  Pregnancy (>amounts found in food)

                  Previous
                  Next:

                  Pregnancy & Lactation

                  Pregnancy Category: N/A

                  Lactation: N/A

                  Pregnancy Categories

                  A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                  B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                  C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                  D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                  X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                  NA: Information not available.

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                  Pharmacology

                  Metabolism: N/A

                  Excretion: N/A

                  Mechanism of Action

                  Beta-thujone, a volatile oil occurs in significant amounts in sage

                  Previous
                  Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
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