salicylic acid topical (Rx, OTC)

Brand and Other Names:Compound W, Compound W for Kids, more...Dr. Scholl's Advanced Pain Relief Corn Removers, Dr. Scholl's Callus Removers, Dr. Scholl's Clear Away, Dr. Scholl's Clear Away OneStep, Dr. Scholl's Clear Away Plantar, Dr. Scholl's Corn Removers, Dr. Scholl's Moisturizing Corn Remover Kit, Dr. Scholl's OneStep Corn Removers, DuoPlant, Durasal, Keralyt, Mediplast, Trans-Ver-Sal AdultPatch, Trans-Ver-Sal PediaPatch, Trans-Ver-Sal PlantarPatch, Sal-Acid, Virasal, Psoriasin Medicated Wash
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

topical liquid

  • 0.5%
  • 1%
  • 2%
  • 3%
  • 6%
  • 12.6%
  • 13.6%
  • 16.7%
  • 17%
  • 17.6%
  • 26%
  • 27.5%

gel

  • 2%
  • 6%
  • 17%

lotion

  • 3%
  • 6%

cream

  • 2%
  • 6%

aerosol/foam

  • 6%

soap

  • 2%
  • 3%

strips

  • 40%

pad

  • 40%

disk

  • 40%

plaster

  • 40%

patch

  • 15%
  • 40%
more...

Plantar Warts/Calluses/Corn

Hydrate skin prior to application by soaking in warm water for 5 min, then use a cloth, brush, or emery board to loosened wart tissue; dry skin thoroughly

Liquid (27.5%): Protect surrounding unaffected skin with petrolatum, then apply liquid to each wart and allow to dry before applying a second application; repeat two application process once or twice daily for up to 6 weeks

Liquid (17%) or gel: Apply to clean dry area at each wart and allow to dry; apply qDay or q12hr up to 12 weeks

Gel (6%): Apply to affected area qDay; may apply at night and rinse off in the morning

Foam: Apply to affected area q12hr; rub into skin until completely absorbed

Patch (15%): Apply directly over affected area qHS and remove in the morning for up to 12 weeks; patch should be trimmed to cover affected area

Patch (40%): Apply directly over affected area and leave in place for 48hr; may repeat for up to 12 weeks; may trim patch to cover affected area or secure with adhesive strips

Plasters/strips: Apply as directed per individual product

Product content varies, check individual labeling

Seborrheic Dermatitis/Psoriasis

Ointment (3%): Apply to plaques or scales on skin up to q6hr (not for use on scalp or face)

Cream (2.5%): Apply to affected area q6-8hr; may be left in place overnight depending on the product

Shampoo (1.8-3%): Massage product into wet hair or affected area and leave in place for several minutes; rinse thoroughly; may apply two or three times/week or as directed by a healthcare professional; may be left in place overnight depending on the product

Foam: Apply to affected area q12hr; rub into skin until completely absorbed

Keratolytic for treating skin/scalp seborrhea or psoriasis

Dosage Forms & Strengths

topical liquid

  • 0.5%
  • 1%
  • 2%
  • 3%
  • 6%
  • 12.6%
  • 13.6%
  • 16.7%
  • 17%
  • 17.6%
  • 26%
  • 27.5%

gel

  • 2%
  • 6%
  • 17%

lotion

  • 3%
  • 6%

cream

  • 2%
  • 6%

aerosol/foam

  • 6%

soap

  • 2%
  • 3%

strips

  • 40%

pad

  • 40%

disk

  • 40%

plaster

  • 40%

patch

  • 15%
  • 40%
more...

Plantar Warts/Calluses/Corn

<12 years

  • Safety & efficacy not established

>12 years

  • Hydrate skin prior to application by soaking in warm water for 5 min, then use a cloth, brush, or emery board to loosened wart tissue; dry skin thoroughly
  • Liquid (27.5%): Protect surrounding unaffected skin with petrolatum, then apply liquid to each wart and allow to dry before applying a second application; repeat two application process once or twice daily for up to 6 weeks
  • Liquid (17%) or gel: Apply to clean dry area at each wart and allow to dry; apply qDay or q12hr up to 12 weeks
  • Gel (6%): Apply to affected area qDay; may apply at night and rinse off in the morning
  • Foam: Apply to affected area q12hr; rub into skin until completely absorbed
  • Patch (15%): Apply directly over affected area qHS and remove in the morning for up to 12 weeks; patch should be trimmed to cover affected area
  • Patch (40%): Apply directly over affected area and leave in place for 48hr; may repeat for up to 12 weeks; may trim patch to cover affected area or secure with adhesive strips
  • Plasters/strips: Apply as directed per individual product Product content varies, check individual labeling
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Adverse Effects

Frequency Not Defined

Stinging/burning of skin

Dizziness

Headache

Tinnitus

Mental confusion

Peeling

Scaling

Burning/irritaion on normal tissue at site of exposure

Hyperventilation

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Warnings

Contraindications

Hypersensitivity

Prolonged use or application to large areas (risk for salicylism)

Virasal

  • Impaired circulaiton (diabetes)
  • Warts with hair growth or on face
  • Birthmarks
  • Moles

Cautions

External topical use only

Avoid contact with eyes

Caution in infants, diabetics, or those with impaired circulation (diabetes)

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Pregnancy & Lactation

Pregnancy category: C

Lactation: Unknown

Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

more...
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Pharmacology

Mechanism of Action

Dissolves the intracellular cement that causes the hyperkeratotic tissue to swell, macerate, soften, and desquamate

Product is keratolytic at 3-6% and destructive at concentrations >6%; concentrations of 6-60% are used to remove corns and warts in the treatment of psoriasis and other keratotic disorders

Pharmacokinetics

Absorption: None with normal percutaneous use

Peak plasma time: Within 5 hours with occlusion is used

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Images

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Formulary

FormularyPatient Discounts

Adding plans allows you to compare formulary status to other drugs in the same class.

To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

Adding plans allows you to:

  • View the formulary and any restrictions for each plan.
  • Manage and view all your plans together – even plans in different states.
  • Compare formulary status to other drugs in the same class.
  • Access your plan list on any device – mobile or desktop.

The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

Tier Description
1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC NOT COVERED – Drugs that are not covered by the plan.
Code Definition
PA Prior Authorization
Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL Quantity Limits
Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST Step Therapy
Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR Other Restrictions
Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.