Indication-specific dosing for Cordyceps Sinensis, CordyMax (cordyceps), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.

Sections

Sections Cordyceps
Suggested Dosing
Suggested Uses
Interactions
Warnings
Pregnancy
Pharmacology

Suggested Dosing

3 g/d fermented in tea

1050 mg extract BID-TID

Standardized to 0.14% adenosine

Suggested Uses

Stimulant/tonic/adaptogen

Enhance athletic performance

Strengthen immune response; treatment of liver disorders

Efficacy

Insufficent reliable evidence to rate use in chemotherpay, aminoglycoside induced nephrotoxicity, cyclosporine induced nephrotoxicity and hepatitis B

Possibly ineffective for athletic performance

Interaction Checker

Enter a drug name and Cordyceps

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Contraindicated

Serious - Use Alternative

Significant - Monitor Closely

Minor

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Contraindicated (0)

Serious - Use Alternative (0)

Monitor Closely (68)

aceclofenac
aceclofenac and cordyceps both increase anticoagulation. Use Caution/Monitor.
acemetacin
acemetacin and cordyceps both increase anticoagulation. Use Caution/Monitor.
agrimony
agrimony and cordyceps both increase anticoagulation. Use Caution/Monitor.
alfalfa
alfalfa and cordyceps both increase anticoagulation. Use Caution/Monitor.
alteplase
alteplase and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
American ginseng
American ginseng and cordyceps both increase anticoagulation. Use Caution/Monitor.
antithrombin alfa
antithrombin alfa and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
antithrombin III
antithrombin III and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
argatroban
argatroban and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
aspirin
aspirin and cordyceps both increase anticoagulation. Use Caution/Monitor.
aspirin rectal
aspirin rectal and cordyceps both increase anticoagulation. Use Caution/Monitor.
aspirin/citric acid/sodium bicarbonate
aspirin/citric acid/sodium bicarbonate and cordyceps both increase anticoagulation. Use Caution/Monitor.
bemiparin
bemiparin and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
bivalirudin
bivalirudin and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
celecoxib
celecoxib and cordyceps both increase anticoagulation. Use Caution/Monitor.
choline magnesium trisalicylate
choline magnesium trisalicylate and cordyceps both increase anticoagulation. Use Caution/Monitor.
cinnamon
cinnamon and cordyceps both increase anticoagulation. Use Caution/Monitor.
dabigatran
dabigatran and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
dalteparin
dalteparin and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
diclofenac
diclofenac and cordyceps both increase anticoagulation. Use Caution/Monitor.
diflunisal
diflunisal and cordyceps both increase anticoagulation. Use Caution/Monitor.
dong quai
cordyceps and dong quai both increase anticoagulation. Use Caution/Monitor.
enoxaparin
enoxaparin and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
epoprostenol
cordyceps and epoprostenol both increase anticoagulation. Use Caution/Monitor.
etodolac
etodolac and cordyceps both increase anticoagulation. Use Caution/Monitor.
fennel
cordyceps and fennel both increase anticoagulation. Use Caution/Monitor.
fenoprofen
fenoprofen and cordyceps both increase anticoagulation. Use Caution/Monitor.
feverfew
cordyceps and feverfew both increase anticoagulation. Use Caution/Monitor.
flurbiprofen
flurbiprofen and cordyceps both increase anticoagulation. Use Caution/Monitor.
fondaparinux
fondaparinux and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
forskolin
cordyceps and forskolin both increase anticoagulation. Use Caution/Monitor.
garlic
cordyceps and garlic both increase anticoagulation. Use Caution/Monitor.
ginger
cordyceps and ginger both increase anticoagulation. Use Caution/Monitor.
ginkgo biloba
cordyceps and ginkgo biloba both increase anticoagulation. Use Caution/Monitor.
heparin
heparin and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
horse chestnut seed
cordyceps and horse chestnut seed both increase anticoagulation. Use Caution/Monitor.
ibuprofen
ibuprofen and cordyceps both increase anticoagulation. Use Caution/Monitor.
ibuprofen IV
ibuprofen IV and cordyceps both increase anticoagulation. Use Caution/Monitor.
indomethacin
indomethacin and cordyceps both increase anticoagulation. Use Caution/Monitor.
ketoprofen
ketoprofen and cordyceps both increase anticoagulation. Use Caution/Monitor.
ketorolac
ketorolac and cordyceps both increase anticoagulation. Use Caution/Monitor.
ketorolac intranasal
ketorolac intranasal and cordyceps both increase anticoagulation. Use Caution/Monitor.
lornoxicam
lornoxicam and cordyceps both increase anticoagulation. Use Caution/Monitor.
meclofenamate
meclofenamate and cordyceps both increase anticoagulation. Use Caution/Monitor.
mefenamic acid
mefenamic acid and cordyceps both increase anticoagulation. Use Caution/Monitor.
meloxicam
meloxicam and cordyceps both increase anticoagulation. Use Caution/Monitor.
mistletoe
cordyceps increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.
nabumetone
nabumetone and cordyceps both increase anticoagulation. Use Caution/Monitor.
naproxen
naproxen and cordyceps both increase anticoagulation. Use Caution/Monitor.
nettle
cordyceps increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.
oxaprozin
oxaprozin and cordyceps both increase anticoagulation. Use Caution/Monitor.
panax ginseng
cordyceps and panax ginseng both increase anticoagulation. Use Caution/Monitor.
parecoxib
parecoxib and cordyceps both increase anticoagulation. Use Caution/Monitor.
pau d'arco
cordyceps and pau d'arco both increase anticoagulation. Use Caution/Monitor.
phenindione
phenindione and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
phytoestrogens
cordyceps and phytoestrogens both increase anticoagulation. Use Caution/Monitor.
piroxicam
piroxicam and cordyceps both increase anticoagulation. Use Caution/Monitor.
protamine
protamine and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
reishi
cordyceps and reishi both increase anticoagulation. Use Caution/Monitor.
reteplase
reteplase and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
salicylates (non-asa)
salicylates (non-asa) and cordyceps both increase anticoagulation. Use Caution/Monitor.
salsalate
salsalate and cordyceps both increase anticoagulation. Use Caution/Monitor.
Siberian ginseng
cordyceps and Siberian ginseng both increase anticoagulation. Use Caution/Monitor.
sulfasalazine
sulfasalazine and cordyceps both increase anticoagulation. Use Caution/Monitor.
sulindac
sulindac and cordyceps both increase anticoagulation. Use Caution/Monitor.
tenecteplase
tenecteplase and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
tolfenamic acid
tolfenamic acid and cordyceps both increase anticoagulation. Use Caution/Monitor.
tolmetin
tolmetin and cordyceps both increase anticoagulation. Use Caution/Monitor.

Minor (15)

amikacin
cordyceps decreases toxicity of amikacin by unspecified interaction mechanism. Minor/Significance Unknown.
anamu
anamu and cordyceps both increase anticoagulation. Minor/Significance Unknown.
cyclosporine
cordyceps decreases toxicity of cyclosporine by unspecified interaction mechanism. Minor/Significance Unknown.
danshen
cordyceps and danshen both increase anticoagulation. Minor/Significance Unknown.
devil's claw
cordyceps and devil's claw both increase anticoagulation. Minor/Significance Unknown.
gentamicin
cordyceps decreases toxicity of gentamicin by unspecified interaction mechanism. Minor/Significance Unknown.
isocarboxazid
cordyceps increases effects of isocarboxazid by pharmacodynamic synergism. Minor/Significance Unknown.
linezolid
cordyceps increases effects of linezolid by pharmacodynamic synergism. Minor/Significance Unknown.
neomycin PO
cordyceps decreases toxicity of neomycin PO by unspecified interaction mechanism. Minor/Significance Unknown.
paromomycin
cordyceps decreases toxicity of paromomycin by unspecified interaction mechanism. Minor/Significance Unknown.
phenelzine
cordyceps increases effects of phenelzine by pharmacodynamic synergism. Minor/Significance Unknown.
prednisolone
cordyceps decreases effects of prednisolone by pharmacodynamic antagonism. Minor/Significance Unknown. Cordyceps protects T & NK cells from immunosuppressive drug effects.
streptomycin
cordyceps decreases toxicity of streptomycin by unspecified interaction mechanism. Minor/Significance Unknown.
tobramycin
cordyceps decreases toxicity of tobramycin by unspecified interaction mechanism. Minor/Significance Unknown.
tranylcypromine
cordyceps increases effects of tranylcypromine by pharmacodynamic synergism. Minor/Significance Unknown.

aceclofenac
Monitor Closely (1)aceclofenac and cordyceps both increase anticoagulation. Use Caution/Monitor.
acemetacin
Monitor Closely (1)acemetacin and cordyceps both increase anticoagulation. Use Caution/Monitor.
agrimony
Monitor Closely (1)agrimony and cordyceps both increase anticoagulation. Use Caution/Monitor.
alfalfa
Monitor Closely (1)alfalfa and cordyceps both increase anticoagulation. Use Caution/Monitor.
alteplase
Monitor Closely (1)alteplase and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
American ginseng
Monitor Closely (1)American ginseng and cordyceps both increase anticoagulation. Use Caution/Monitor.
amikacin
Minor (1)cordyceps decreases toxicity of amikacin by unspecified interaction mechanism. Minor/Significance Unknown.
anamu
Minor (1)anamu and cordyceps both increase anticoagulation. Minor/Significance Unknown.
antithrombin alfa
Monitor Closely (1)antithrombin alfa and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
antithrombin III
Monitor Closely (1)antithrombin III and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
argatroban
Monitor Closely (1)argatroban and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
aspirin
Monitor Closely (1)aspirin and cordyceps both increase anticoagulation. Use Caution/Monitor.
aspirin rectal
Monitor Closely (1)aspirin rectal and cordyceps both increase anticoagulation. Use Caution/Monitor.
aspirin/citric acid/sodium bicarbonate
Monitor Closely (1)aspirin/citric acid/sodium bicarbonate and cordyceps both increase anticoagulation. Use Caution/Monitor.
bemiparin
Monitor Closely (1)bemiparin and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
bivalirudin
Monitor Closely (1)bivalirudin and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
celecoxib
Monitor Closely (1)celecoxib and cordyceps both increase anticoagulation. Use Caution/Monitor.
choline magnesium trisalicylate
Monitor Closely (1)choline magnesium trisalicylate and cordyceps both increase anticoagulation. Use Caution/Monitor.
cinnamon
Monitor Closely (1)cinnamon and cordyceps both increase anticoagulation. Use Caution/Monitor.
cyclosporine
Minor (1)cordyceps decreases toxicity of cyclosporine by unspecified interaction mechanism. Minor/Significance Unknown.
dabigatran
Monitor Closely (1)dabigatran and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
dalteparin
Monitor Closely (1)dalteparin and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
danshen
Minor (1)cordyceps and danshen both increase anticoagulation. Minor/Significance Unknown.
devil's claw
Minor (1)cordyceps and devil's claw both increase anticoagulation. Minor/Significance Unknown.
diclofenac
Monitor Closely (1)diclofenac and cordyceps both increase anticoagulation. Use Caution/Monitor.
diflunisal
Monitor Closely (1)diflunisal and cordyceps both increase anticoagulation. Use Caution/Monitor.
dong quai
Monitor Closely (1)cordyceps and dong quai both increase anticoagulation. Use Caution/Monitor.
enoxaparin
Monitor Closely (1)enoxaparin and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
epoprostenol
Monitor Closely (1)cordyceps and epoprostenol both increase anticoagulation. Use Caution/Monitor.
etodolac
Monitor Closely (1)etodolac and cordyceps both increase anticoagulation. Use Caution/Monitor.
fennel
Monitor Closely (1)cordyceps and fennel both increase anticoagulation. Use Caution/Monitor.
fenoprofen
Monitor Closely (1)fenoprofen and cordyceps both increase anticoagulation. Use Caution/Monitor.
feverfew
Monitor Closely (1)cordyceps and feverfew both increase anticoagulation. Use Caution/Monitor.
flurbiprofen
Monitor Closely (1)flurbiprofen and cordyceps both increase anticoagulation. Use Caution/Monitor.
fondaparinux
Monitor Closely (1)fondaparinux and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
forskolin
Monitor Closely (1)cordyceps and forskolin both increase anticoagulation. Use Caution/Monitor.
garlic
Monitor Closely (1)cordyceps and garlic both increase anticoagulation. Use Caution/Monitor.
gentamicin
Minor (1)cordyceps decreases toxicity of gentamicin by unspecified interaction mechanism. Minor/Significance Unknown.
ginger
Monitor Closely (1)cordyceps and ginger both increase anticoagulation. Use Caution/Monitor.
ginkgo biloba
Monitor Closely (1)cordyceps and ginkgo biloba both increase anticoagulation. Use Caution/Monitor.
heparin
Monitor Closely (1)heparin and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
horse chestnut seed
Monitor Closely (1)cordyceps and horse chestnut seed both increase anticoagulation. Use Caution/Monitor.
ibuprofen
Monitor Closely (1)ibuprofen and cordyceps both increase anticoagulation. Use Caution/Monitor.
ibuprofen IV
Monitor Closely (1)ibuprofen IV and cordyceps both increase anticoagulation. Use Caution/Monitor.
indomethacin
Monitor Closely (1)indomethacin and cordyceps both increase anticoagulation. Use Caution/Monitor.
isocarboxazid
Minor (1)cordyceps increases effects of isocarboxazid by pharmacodynamic synergism. Minor/Significance Unknown.
ketoprofen
Monitor Closely (1)ketoprofen and cordyceps both increase anticoagulation. Use Caution/Monitor.
ketorolac
Monitor Closely (1)ketorolac and cordyceps both increase anticoagulation. Use Caution/Monitor.
ketorolac intranasal
Monitor Closely (1)ketorolac intranasal and cordyceps both increase anticoagulation. Use Caution/Monitor.
linezolid
Minor (1)cordyceps increases effects of linezolid by pharmacodynamic synergism. Minor/Significance Unknown.
lornoxicam
Monitor Closely (1)lornoxicam and cordyceps both increase anticoagulation. Use Caution/Monitor.
meclofenamate
Monitor Closely (1)meclofenamate and cordyceps both increase anticoagulation. Use Caution/Monitor.
mefenamic acid
Monitor Closely (1)mefenamic acid and cordyceps both increase anticoagulation. Use Caution/Monitor.
meloxicam
Monitor Closely (1)meloxicam and cordyceps both increase anticoagulation. Use Caution/Monitor.
mistletoe
Monitor Closely (1)cordyceps increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.
nabumetone
Monitor Closely (1)nabumetone and cordyceps both increase anticoagulation. Use Caution/Monitor.
naproxen
Monitor Closely (1)naproxen and cordyceps both increase anticoagulation. Use Caution/Monitor.
neomycin PO
Minor (1)cordyceps decreases toxicity of neomycin PO by unspecified interaction mechanism. Minor/Significance Unknown.
nettle
Monitor Closely (1)cordyceps increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.
oxaprozin
Monitor Closely (1)oxaprozin and cordyceps both increase anticoagulation. Use Caution/Monitor.
panax ginseng
Monitor Closely (1)cordyceps and panax ginseng both increase anticoagulation. Use Caution/Monitor.
parecoxib
Monitor Closely (1)parecoxib and cordyceps both increase anticoagulation. Use Caution/Monitor.
paromomycin
Minor (1)cordyceps decreases toxicity of paromomycin by unspecified interaction mechanism. Minor/Significance Unknown.
pau d'arco
Monitor Closely (1)cordyceps and pau d'arco both increase anticoagulation. Use Caution/Monitor.
phenelzine
Minor (1)cordyceps increases effects of phenelzine by pharmacodynamic synergism. Minor/Significance Unknown.
phenindione
Monitor Closely (1)phenindione and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
phytoestrogens
Monitor Closely (1)cordyceps and phytoestrogens both increase anticoagulation. Use Caution/Monitor.
piroxicam
Monitor Closely (1)piroxicam and cordyceps both increase anticoagulation. Use Caution/Monitor.
prednisolone
Minor (1)cordyceps decreases effects of prednisolone by pharmacodynamic antagonism. Minor/Significance Unknown. Cordyceps protects T & NK cells from immunosuppressive drug effects.
protamine
Monitor Closely (1)protamine and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
reishi
Monitor Closely (1)cordyceps and reishi both increase anticoagulation. Use Caution/Monitor.
reteplase
Monitor Closely (1)reteplase and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
salicylates (non-asa)
Monitor Closely (1)salicylates (non-asa) and cordyceps both increase anticoagulation. Use Caution/Monitor.
salsalate
Monitor Closely (1)salsalate and cordyceps both increase anticoagulation. Use Caution/Monitor.
Siberian ginseng
Monitor Closely (1)cordyceps and Siberian ginseng both increase anticoagulation. Use Caution/Monitor.
streptomycin
Minor (1)cordyceps decreases toxicity of streptomycin by unspecified interaction mechanism. Minor/Significance Unknown.
sulfasalazine
Monitor Closely (1)sulfasalazine and cordyceps both increase anticoagulation. Use Caution/Monitor.
sulindac
Monitor Closely (1)sulindac and cordyceps both increase anticoagulation. Use Caution/Monitor.
tenecteplase
Monitor Closely (1)tenecteplase and cordyceps both increase anticoagulation. Modify Therapy/Monitor Closely.
tobramycin
Minor (1)cordyceps decreases toxicity of tobramycin by unspecified interaction mechanism. Minor/Significance Unknown.
tolfenamic acid
Monitor Closely (1)tolfenamic acid and cordyceps both increase anticoagulation. Use Caution/Monitor.
tolmetin
Monitor Closely (1)tolmetin and cordyceps both increase anticoagulation. Use Caution/Monitor.
tranylcypromine
Minor (1)cordyceps increases effects of tranylcypromine by pharmacodynamic synergism. Minor/Significance Unknown.

Contraindications

Lactation, pregnancy

Pregnancy & Lactation

Pregnancy Category: N/A

Lactation: N/A

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Mechanism of Action

Stim WBCs and interleukins; possibly cytotoxic to cancer cells

Increase ATP level in cells

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

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