SARS-CoV-2 vaccine, genetic code (Pending FDA Approval)

Brand and Other Names:COVID-19 vaccine, genetic code
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Dosing & Uses

COVID-19 Disease Prevention

Pending FDA approval for prevention of coronavirus disease 2019 (COVID-19) infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Several vaccines are in late phase 3 clinical trials in the United States

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Pharmacology

Mechanism of Action

The goal is to elicit long-term antigen-specific antibody responses by plasma cells and to develop persistent T-cell and B-cell memory of the antigen (ie, humoral and cellular immune response)

Genetic vaccines consist only of DNA (as plasmids) or RNA (as mRNA), which is taken up by cells and translated into protein

Transfected cells then express the antigen encoded on the plasmid resulting in an immune response

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.