debamestrocel (Pending FDA Approval)

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Dosing & Uses

Amyotrophic Lateral Sclerosis

Pending FDA approval for amyotrophic lateral sclerosis (ALS)

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Pharmacology

Mechanism of Action

Mesenchymal stromal cells (MSC) enriched from the patient's own bone marrow that has been induced to secrete neurotrophic factors (NTFs)

Intrathecal delivery of NTFs to the immediate environment of afflicted neurons in ALS is expected to improve survival and slow disease progression and alleviate symptoms

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.