pyrithione zinc (OTC)

Brand and Other Names:Denorex Everyday Dandruff Shampoo, Head & Shoulders Shampoo, more...DHS Zinc Shampoo, Head & Shoulders Dry Scalp, Selsun Blue Itchy Dry Scalp, T/Gel Daily Control, Zincon Shampoo
  • Print

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

shampoo

  • 0.25%
  • 1%
  • 2%

lotion

  • 0.25%

cream

  • 0.25%

conditioner

  • 0.5%

soap bar

  • 2%

Seborrhea

Shampoo: Apply to wet hair/scalp, lather, then rinse well; may follow with conditioner

Bar: May use on body and or scalp; wet area to be applied to; massage in and rinse

Safety and efficacy not established

Next:

Adverse Effects

Frequency Not Defined

Stinging/burning of scalp

Desquamation

Irritation of the skin (rare)

Previous
Next:

Warnings

Contraindications

Hypersensitivity

Cautions

Topical use only

Avoid contact with eyes

Previous
Next:

Pregnancy & Lactation

Pregnancy category: C

Lactation: Unknown

Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Previous
Next:

Pharmacology

Mechanism of Action

Binds to hair and external skin layers; reduces turnover rate of cells; toxicity nonspecific for epidermal cells; cytostatic agent

Previous
Next:

Images

Previous
Next:
Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.