Dermabond (2-octyl cyanoacrylate) dosing, indications, interactions, adverse effects, and more.

Sections

Sections 2-octyl cyanoacrylate
Dosing & Uses
Adverse Effects
Warnings
Pregnancy
Pharmacology
Images
Patient Handout
Formulary

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

prefilled applicator

Topical liquid adhesive available in boxes of 6 or 12

Topical Skin Adhesive

Indicated for topical application to hold closed easily approximated skin edges of wounds

May be used for surgical incisions (including punctures from minimally invasive surgery) and trauma-induced lacerations, not under tension, that are simple and thoroughly cleansed

May be used with, but not in place of, deep dermal stitches

Apply in multiple thin layers to approximated wound edges, with wound in horizontal position

Dosage Forms & Strengths

prefilled applicator

Topical liquid adhesive available in boxes of 6 or 12

Topical Skin Adhesive

Indicated for topical application to hold closed easily approximated skin edges of wounds

May be used for surgical incisions (including punctures from minimally invasive surgery) and trauma-induced lacerations, not under tension, that are simple and thoroughly cleansed

May be used with, but not in place of, deep dermal stitches

Apply in multiple thin layers to approximated wound edges, with wound in horizontal position

>10%

Erythema (11.5%)

1-10%

Dehiscence with need for retreatment (2.5%)

Edema (9.7%)

Pain (6.1%)

Suspected infection (3.6%)

Warmth (1.3%)

Contraindications

Wounds with active infection, gangrene, or of decubitus etiology

Use on eye, mucosal surfaces, skin exposed to body fluids, or skin with dense hair

Hypersensitivity to cyanoacrylate or formaldehyde

Cautions

Use only on wounds that have been cleaned & debrided; do not use on moist wounds

Do not use on high-tension areas (knuckles, elbows, etc)

Pregnancy & Lactation

Pregnancy Category: no studies found

Lactation: no studies found

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Mechanism of Action

Liquid polymerizes to form adhesive

Images

No images available for this drug.

Patient Handout

A Patient Handout is not currently available for this monograph.

Formulary

FormularyPatient Discounts

Adding plans allows you to compare formulary status to other drugs in the same class.

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Create Your List of Plans

Adding plans allows you to:

View the formulary and any restrictions for each plan.
Manage and view all your plans together – even plans in different states.
Compare formulary status to other drugs in the same class.
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The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

View explanations for tiers and restrictions

Tier	Description
1	This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2	This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC	NOT COVERED – Drugs that are not covered by the plan.

Code	Definition
PA	Prior Authorization Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL	Quantity Limits Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST	Step Therapy Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR	Other Restrictions Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

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