DermOtic (fluocinolone acetonide, otic) dosing, indications, interactions, adverse effects, and more

Sections

Sections fluocinolone acetonide, otic
Dosing & Uses
Adverse Effects
Warnings
Pregnancy
Pharmacology
Images
Patient Handout
Formulary

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

otic oil

0.01%

Eczematous External Otitis

Instill 5 gtt into affected ear(s) twice daily for 7-14 days

Dosage Forms & Strengths

otic oil

0.01%

Eczematous External Otitis

<2 years: Safety and efficacy not established

>2 years: Instill 5 gtt into affected ear(s) twice daily for 7-14 days

Frequency Not Defined

Burning

Itching

Irritation dryness

Folliculitis

Acneiform eruption

Hypopigmentation, perioral dermatitis

Allergic contact dermatitis

Secondary infection

Skin atrophy

Striae

Miliaria

Ear infection

Contraindications

Hypersensitivity

Contains peanut oil; contraindicated in peanut allergic individuals

Viral infections of external canal including varicella & herpes simplex infections

Cautions

Risk of HPA axis suppression especially in young children or patients receiving high doses for prolonged periods

Discontinue if ear infection occurs; may also mask infections

Contact dermatitis may occur; diagnosed as failure to heal

Pregnancy & Lactation

Pregnancy Category: C

Lactation: Excretion in milk unknown; use with caution

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Mechanism of Action

Low-to-medium potency corticosteroid; elicits anti-inflammatory, antipruritic, and vasoconstrictive effects; induces phospholipase A2 inhibitory proteins that are thought to suppress inflammatory mediators (eg, prostaglandins, leukotrienes) by inhibiting arachidonic acid

Images

No images available for this drug.

Patient Handout

A Patient Handout is not currently available for this monograph.

Formulary

FormularyPatient Discounts

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The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

View explanations for tiers and restrictions

Tier	Description
1	This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2	This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC	NOT COVERED – Drugs that are not covered by the plan.

Code	Definition
PA	Prior Authorization Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL	Quantity Limits Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST	Step Therapy Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR	Other Restrictions Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

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