Indication-specific dosing for dinagen, myocalm, nootropil, qropi (piracetam), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.

Sections

Sections Piracetam
Suggested Dosing
Suggested Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology

Suggested Dosing

AdultPediatric

1.6-9.6 g/day PO

<16 years old: not recommended

Suggested Uses

Alzheimers disease, dementia, memory dysfunction, alcoholism, Raynaud's phenomenon, DVT, stroke, tardive dyskinesia, dyslexia, brain injury, vertigo

Efficacy

Approved in many European countries for myoclonus, aging-related conditions (dementia, Alzheimer's)

Some clinical studies show efficacy in dyslexia, brain injury, vertigo

Interaction Checker

Enter a drug name and Piracetam

No Results

No Interactions Found

Interactions Found

Contraindicated

Serious - Use Alternative

Significant - Monitor Closely

Minor

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Contraindicated (0)

Serious - Use Alternative (0)

Monitor Closely (7)

cilostazol
piracetam increases effects of cilostazol by pharmacodynamic synergism. Use Caution/Monitor.
clopidogrel
piracetam increases effects of clopidogrel by pharmacodynamic synergism. Use Caution/Monitor.
dipyridamole
piracetam increases effects of dipyridamole by pharmacodynamic synergism. Use Caution/Monitor.
eptifibatide
piracetam increases effects of eptifibatide by pharmacodynamic synergism. Use Caution/Monitor.
prasugrel
piracetam increases effects of prasugrel by pharmacodynamic synergism. Use Caution/Monitor.
ticlopidine
piracetam increases effects of ticlopidine by pharmacodynamic synergism. Use Caution/Monitor.
tirofiban
piracetam increases effects of tirofiban by pharmacodynamic synergism. Use Caution/Monitor.

Minor (3)

levothyroxine
piracetam, levothyroxine. Mechanism: unknown. Minor/Significance Unknown. Combination of piracetam and T3+T4 produced confusion, sleep disorder in single case.
liothyronine
piracetam, liothyronine. Mechanism: unknown. Minor/Significance Unknown. Combination of piracetam and T3+T4 produced confusion, sleep disorder in single case.
thyroid desiccated
piracetam, thyroid desiccated. Mechanism: unknown. Minor/Significance Unknown. Combination of piracetam and T3+T4 produced confusion, sleep disorder in single case.

Frequency not defined

diarrhea, weight gain, somnolence, insomnia, nervousness, depression, hyperkinesia, rash

Contraindications

Hepatic impairment

Severe renal impairment

Pregnancy, lactation

Hemorrhagic diathesis

Cautions

Avoid abrupt withdrawal

Elderly

Renal impairment

May impair ability to drive or perform hazardous tasks

Blood dyscrasias

Pregnancy & Lactation

Pregnancy Category: contraindicated

Lactation: contraindicated

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Pharmacology

Peak Plasma Time: 1.5 hr

Half-Life: 5 hr

Bioavailability: ~100%

Metabolism: no identified metabolites

Excretion: urine

Mechanism of Action

Unknown, GABA analog

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

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