donanemab (Pending FDA Approval)

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Dosing & Uses

Alzheimer Disease

Pending FDA approval for treatment of early Alzheimer disease

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Pharmacology

Mechanism of Action

Humanized IgG1 monoclonal antibody that recognizes amyloid beta(p3-42), a pyroglutamate for of amyloid beta that is aggregated in amyloid plaques; helps to clear existing amyloid plaque burden from brain

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Images

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Patient Handout

A Patient Handout is not currently available for this monograph.
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.