polymyxin B/bacitracin topical (OTC)

Brand and Other Names:Double Antibiotic Ointment, Polysporin
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

polymyxin B/bacitracin topical

topical ointment, cream

  • (10,000unit/500unit)/g

Treatment/Prophylaxis Superficial Skin Infection

Apply topically qD-TID

Other Information

For gram-pos & gram-neg infections

Good broad spectrum coverage

Does not cause allergic contact dermatitis like neosporin or other neomycin containing topical antibiotic preparations

Dosage Forms & Strengths

polymyxin B/bacitracin topical

topical ointment, cream

  • (10,000unit/500unit)/g

Treatment/Prevention Superficial Skin Infection

Apply Topically qD-TID

Other Information

For gram-pos & gram-neg infections

Good broad spectrum coverage

Does not cause allergic contact dermatitis like neosporin or other neomycin containing topical antibiotic preparations

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Interactions

Interaction Checker

and polymyxin B/bacitracin topical

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    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            <1%

            Allergic contact dermatitis

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            Warnings

            Contraindications

            Hypersensitivity

            Not for ophthalmic use or over large areas of body

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            Pregnancy & Lactation

            Pregnancy Category: C

            Lactation: unknown if distributed in breast milk

            Pregnancy Categories

            A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA: Information not available.

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            Pharmacology

            See individual monograph for further details:

            Bacitracin

            Mechanism of Action

            Antibacterial

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            Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.