aluminum chloride topical (OTC)

Brand and Other Names:Drysol, Xerac AC, more...Hypercare Solution
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

topical solution

  • 6.25% (Drysol Mild, Xerac AC)
  • 12% (Drysol)
  • 20% (Drysol Extra Strength)
more...

Hyperhidrosis

Indicated for severe, recalcitrant hyperhidrosis

Apply to affected area qHS; once excessive sweating decreases (typically after 2 or more treatments), decrease application to 1-2 times/week

May cover treated area with plastic wrap held in place by tight fitting t-shirt, mitten, or sock; do not hold in place with tape

Also see Topical Administration

Dosage Forms & Strengths

topical solution

  • 6.25% (Drysol Mild, Xerac AC)
  • 12% (Drysol)
  • 20% (Drysol Extra Strength)
more...

Recalcitrant Hyperhidrosis

Infants and children: Safety and efficacy not established

Adolescents: Apply to affected area qDay at bedtime; once excessive sweating decreases (typically after 2 or more treatments), decrease application to 1-2 times/week

May cover treated area with plastic wrap held in place by tight fitting t-shirt, mitten, or sock; do not hold in place with tape

Also see Topical Administration

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Adverse Effects

Frequency Not Defined

Irritation

Itching

Tingling

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Warnings

Contraindications

Hypersensitivity

Cautions

Do not apply to broken, irritated, or recently shaved skin

Discontinue use if irritation/sensitization occurs

External use only; avoid eyes

May harm certain metals or fabrics

Flammable: Do not use near open flame

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Pregnancy & Lactation

Pregnancy Category: C

Lactation: Unknown whether distributed in breast milk, caution advised

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

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Pharmacology

Mechanism of Action

Astringent

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Administration

Topical Administration

Apply to completely dry skin to avoid irritation

Do not apply to broken, irritated, or recently shaved skin

20% suitable for axillae, palms, and soles

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Images

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.