celiprolol (Pending FDA Approval)

Brand and Other Names:Edsivo
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Dosing & Uses

Ehlers-Danlos Syndrome

Pending FDA for treatment of vascular Ehlers-Danlos syndrome (vEDS)

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Pharmacology

Mechanism of Action

Theorized to provide clinical benefit for vEDS by promoting normal collagen synthesis in blood vessels; may also shift pressure load away from vessels most prone to dissection and rupture

Beta1 receptor antagonist, but elicits partial agonist effects on beta2 receptors; it is also a weak alpha2 receptor antagonist

Lowers blood pressure in patients with hypertension, but not in normotensive patients

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.