mometasone topical (Rx)

Brand and Other Names:Elocon

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

cream/lotion/ointment

  • 0.1%

Inflammatory Hyperkeratotic Dermatosis

Apply cream, lotion or ointment to affected area qDay

Administration

Do not use with occlusive dressings

Other Indications & Uses

Dermatosis-associated inflammation and pruritus

Potency: Medium

Dosage Forms & Strengths

cream/lotion/ointment

  • 0.1%

Inflammatory Hyperkeratotic Dermatosis

<2 years: Safety and efficacy not established

2 years or older: As adults: apply cream, lotion or ointment to affected area qDay

Use beyond 3 weeks not studied

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Interactions

Interaction Checker

and mometasone topical

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            All Interactions Sort By:
             activity indicator 

            Contraindicated (1)

            • mifepristone

              mifepristone, mometasone topical. Either increases toxicity of the other by Other (see comment). Contraindicated. Comment: Mifepristone is contraindicated in patients on long-term corticosteriod treatment due to increase risk of adrenal insufficiency.

            Serious - Use Alternative (1)

            • aldesleukin

              mometasone topical decreases effects of aldesleukin by unspecified interaction mechanism. Avoid or Use Alternate Drug.

            Monitor Closely (5)

            • ceritinib

              mometasone topical decreases effects of ceritinib by Other (see comment). Modify Therapy/Monitor Closely. Comment: Closely monitor for severe hyperglycemia (serum glucose >250 mg/dL) and treat appropriately. Patients with history of diabetes or glucose intolerance are at increased risk. .

            • corticorelin

              mometasone topical decreases effects of corticorelin by pharmacodynamic antagonism. Use Caution/Monitor. Recent or current corticosteroid therapy may blunt the response to corticorelin, potentially interfering with the corticorelin stimulation test results.

            • deferasirox

              mometasone topical decreases effects of deferasirox by unspecified interaction mechanism. Use Caution/Monitor. Due to the risk for GI bleeding and irritation/ulceration associated with deferasirox, exercise caution when using with corticosteroids, that can also cause gastrointestinal ulceration and/or bleeding.

            • hyaluronidase

              mometasone topical decreases effects of hyaluronidase by unspecified interaction mechanism. Modify Therapy/Monitor Closely. Patients receiving larger doses of corticosteriods may not experience the desired clinical response to standard doses of hyaluronidase. Larger doses of hyaluronidase may be required.

            • omacetaxine

              omacetaxine, mometasone topical. Either increases toxicity of the other by Other (see comment). Modify Therapy/Monitor Closely. Comment: Concomitant use with omacetaxine and mometasone topical may enhance the risk of infections and myelosuppression.

            Minor (0)

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              Adverse Effects

              Frequency Not Defined

              Burning

              Itching

              Pruritus

              Rosacea

              Postmarketing Reports

              Irritation

              Dryness

              Folliculitis

              Hypertrichosis

              Acneiform eruptions

              Hypopigmentation

              Perioral dermatitis

              Allergic contact dermatitis

              Secondary infection

              Skin atrophy

              Striae

              Miliaria

              Blurred vision

              Cataracts

              Glaucoma

              Increased intraocular pressure

              Central serous chorioretinopathy

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              Warnings

              Contraindications

              Hypersensitivity

              Cautions

              Safety/efficacy in children use for longer than 3 wk not established; pediatric patients may be more susceptible to systemic toxicity

              Do not use with occlusive dressings

              Not for acne, rosacea, perioral dermatitis, diaper dermatitis

              If concomitant skin infections are present or develop, use appropriate antifungal or antibacterial agent; if favorable response does not occur promptly, therapy should be discontinued until infection has been adequately controlled

              If irritation develops, discontinue therapy and institute appropriate therapy; allergic contact dermatitis with corticosteroids is usually diagnosed by observing failure to heal rather than noting a clinical exacerbation; corroborate observation with appropriate diagnostic patch testing

              Use of topical corticosteroids may increase risk of posterior subcapsular cataracts and glaucoma; cataracts and glaucoma reported in postmarketing experience with therapy; avoid contact with eyes; advise patients to report any visual symptoms and consider referral to ophthalmologist for evaluation

              Endocrine system effects

              • Systemic absorption of topical corticosteroids can produce reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with potential for glucocorticosteroid insufficiency; this may occur during treatment or after withdrawal of treatment
              • Manifestations of Cushing's syndrome, hyperglycemia, and glucosuria can be produced in some patients by systemic absorption of topical corticosteroids while on treatment
              • Factors that predispose a patient using a topical corticosteroid to HPA axis suppression include use of high potency steroids, large treatment surface areas, prolonged use, use of occlusive dressing, altered skin barrier, liver failure and young age
              • Because of potential for systemic absorption, use of topical corticosteroids may require that patients be periodically evaluated for HPA axis suppression; this may be done by using the adrenocorticotropic hormone (ACTH) stimulation test
              • If HPA axis suppression documented, attempt to gradually withdraw drug, to reduce frequency of application, or to substitute a less potent corticosteroid; recovery of HPA axis function is generally prompt upon discontinuation of topical corticosteroids; infrequently, signs and symptoms of glucocorticosteroid insufficiency may occur, requiring supplemental systemic corticosteroids
              • Pediatric patients may be more susceptible to systemic toxicity from equivalent doses due to their larger skin surface to body mass ratios
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              Pregnancy & Lactation

              Pregnancy Category: C

              Lactation: use caution

              Pregnancy Categories

              A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

              B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

              C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

              D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

              X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

              NA: Information not available.

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              Pharmacology

              Absorption: 0.4%

              Metabolism: hepatic P450 enzyme CYP3A4

              Excretion: N/A

              Potency

              Medium

              Relative potency: ointment >cream >lotion >solution

              Very-high: clobetasol, diflorasone diacetate ointment 0.05%, halobetasol

              High: betamethasone dipropionate 0.05%, amcinonide, fluocinonide, desoximetasone, mometasone, diflorasone emollient 0.05%, halcinonide

              Medium: triamcinolone, betamethasone valerate 0.1%, fluticasone, flurandrenolide, fluocinolone 0.025%, hydrocortisone

              Mild: hydrocortisone 0.5, 1, 2.5% base, desonide, alclometasone

              Mechanism of Action

              Anti-inflammatory corticosteroid

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              Images

              BRAND FORM. UNIT PRICE PILL IMAGE
              Nasonex 24hr Allergy nasal
              -
              50 mcg/actuation aerosol
              Asmanex Twisthaler inhalation
              -
              220 mcg/ actuation (14) aerosol
              Asmanex Twisthaler inhalation
              -
              220 mcg/ actuation (120) aerosol
              Asmanex Twisthaler inhalation
              -
              220 mcg/ actuation (60) aerosol
              Asmanex Twisthaler inhalation
              -
              110 mcg/ actuation (30) aerosol
              Asmanex Twisthaler inhalation
              -
              220 mcg/ actuation (30) aerosol
              Asmanex HFA inhalation
              -
              100 mcg/actuation aerosol
              Asmanex HFA inhalation
              -
              200 mcg/actuation aerosol
              Asmanex HFA inhalation
              -
              50 mcg/actuation aerosol
              Sinuva sinus
              -
              1,350 mcg implant
              mometasone nasal
              -
              50 mcg/actuation aerosol
              mometasone nasal
              -
              50 mcg/actuation aerosol
              mometasone nasal
              -
              50 mcg/actuation aerosol
              mometasone topical
              -
              0.1 % cream
              mometasone topical
              -
              0.1 % cream
              mometasone topical
              -
              0.1 % ointment
              mometasone topical
              -
              0.1 % ointment
              mometasone topical
              -
              0.1 % ointment
              mometasone topical
              -
              0.1 % cream
              mometasone topical
              -
              0.1 % cream
              mometasone topical
              -
              0.1 % ointment
              mometasone topical
              -
              0.1 % ointment
              mometasone topical
              -
              0.1 % solution
              mometasone topical
              -
              0.1 % ointment
              mometasone topical
              -
              0.1 % ointment
              mometasone topical
              -
              0.1 % cream
              mometasone topical
              -
              0.1 % cream
              mometasone topical
              -
              0.1 % solution
              mometasone topical
              -
              0.1 % ointment
              mometasone topical
              -
              0.1 % solution
              mometasone topical
              -
              0.1 % solution

              Copyright © 2010 First DataBank, Inc.

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              Patient Handout

              Select a drug:
              Patient Education
              mometasone inhalation

              MOMETASONE HFA INHALER - ORAL INHALATION

              (moe-MET-a-sone)

              COMMON BRAND NAME(S): Asmanex HFA

              USES: Mometasone is used to control and prevent symptoms (such as wheezing and shortness of breath) caused by asthma. Controlling symptoms of asthma helps you maintain your normal activities and decreases time lost from work or school. Mometasone belongs to a class of drugs known as corticosteroids. It works by reducing swelling (inflammation) of the airways in the lungs to make breathing easier.This medication must be used regularly to be effective. It does not work right away and should not be used to relieve sudden asthma attacks. If an asthma attack occurs, use your quick-relief inhaler (such as albuterol, also called salbutamol in some countries) as prescribed.

              HOW TO USE: Read the Patient Information Leaflet and the product instructions provided by your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.Follow the instructions for priming the inhaler if you are using it for the first time or if you have not used it for more than 5 days. When priming the inhaler, make sure to spray away from your face so that you do not get the medication into your eyes.Shake the inhaler well before each use. Inhale this medication by mouth as directed by your doctor, usually twice a day (morning and evening). The dosage is based on your medical condition and response to treatment.If two inhalations/puffs are prescribed, wait at least one minute between them. If you are using other inhalers at the same time, wait at least 1 minute between the use of each medication, and use this drug (the corticosteroid) last.To prevent dry mouth, hoarseness, and oral yeast infections from developing, gargle, rinse your mouth with water and spit out after each use. Do not swallow the rinse water.Clean the mouthpiece once a week with a dry tissue. Do not wet the inhaler. Do not take the inhaler apart.Use this medication regularly to get the most benefit from it. This medication works best if used at evenly spaced intervals. To help you remember, use it at the same times each day. Do not increase your dose, use this drug more often, or stop using it without first consulting your doctor.If you are regularly taking a different corticosteroid by mouth (such as prednisone), you should not stop taking it unless directed by your doctor. Some conditions (such as asthma, allergies) may become worse when the drug is suddenly stopped. If you suddenly stop taking the drug, you may also have withdrawal symptoms (such as weakness, weight loss, nausea, muscle pain, headache, tiredness, dizziness). To help prevent withdrawal, your doctor may slowly lower the dose of your old medication after you begin using mometasone. Tell your doctor or pharmacist right away if you have withdrawal. See also Precautions section.It may take 1-2 weeks before you get the full benefit of this drug. Tell your doctor if your symptoms do not improve or if they worsen.Learn which of your inhalers you should use every day (controller drugs) and which you should use if your breathing suddenly worsens (quick-relief drugs). Ask your doctor ahead of time what you should do if you have new or worsening cough or shortness of breath, wheezing, increased sputum, worsening peak flow meter readings, waking up at night with trouble breathing, if you use your quick-relief inhaler more often (more than 2 days a week), or if your quick-relief inhaler does not seem to be working well. Learn when you can treat sudden breathing problems by yourself and when you must get medical help right away.

              SIDE EFFECTS: See also Precautions section.Dry/irritated throat, hoarseness, or coughing may occur as your body adjusts to the medication. If any of these effects last or get worse, tell your doctor or pharmacist promptly.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including: white patches in your mouth or on your tongue, signs of infection (such as sore throat that doesn't go away, fever, chills), mental/mood changes (such as depression, mood swings, agitation), vision problems, increased thirst/urination, easy bruising/bleeding, bone pain.Rarely, this medication may cause sudden severe wheezing/trouble breathing immediately after you use it. If this occurs, use your quick-relief inhaler and get medical help right away.A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

              PRECAUTIONS: Before using mometasone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: current/past infections (such as tuberculosis, herpes), bone loss (osteoporosis), eye problems (such as cataracts, glaucoma).If you have switched from a corticosteroid taken by mouth (such as prednisone tablets) to this inhaler within the past 12 months, or if you have been using this product in higher-than-usual doses for a long time, it may be more difficult for your body to respond to physical stress. Before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used a corticosteroid taken by mouth within the past 12 months. Tell your doctor right away if you develop unusual/extreme tiredness or weight loss. Carry a warning card or medical ID bracelet that says you use (or have used) corticosteroid medications.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).This medication may mask signs of infection. It can make you more likely to get infections or may make current infections worse. Stay away from anyone who has an infection that may easily spread (such as chickenpox, COVID-19, measles, flu). Talk to your doctor if you have been exposed to an infection or for more details.This medication may temporarily slow down a child's growth if used for a long time. However, poorly controlled asthma can also slow down growth. See the doctor regularly so your child's height can be checked.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

              DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

              OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

              NOTES: Do not share this medication with others.Lab and/or medical tests (such as cortisol levels, lung function, eye exams, bone density tests) should be done while you are using this medication. Keep all medical and lab appointments. Consult your doctor for more details.Learn to use a peak flow meter, use it daily, and promptly report worsening breathing problems (such as readings in the yellow/red range or increased use of quick-relief inhalers).Avoid allergens/irritants such as smoke, pollen, pet dander, dust, or molds that may worsen breathing problems. Because the flu virus can also worsen breathing problems, ask your doctor or pharmacist if you should have a flu shot every year.In adults, this medication can increase the risk of bone loss (osteoporosis) if used for a long time. Talk with your doctor about your risk, and about available treatments for osteoporosis. Lifestyle changes that help promote healthy bones include increasing weight-bearing exercise, stopping smoking, limiting alcohol, and eating well-balanced meals that contain adequate calcium and vitamin D. You may also need to take calcium and vitamin D supplements. Consult your doctor for specific advice. To help prevent osteoporosis later in life, encourage children to exercise and eat a healthy diet (including calcium).

              MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

              STORAGE: Store at room temperature. Do not puncture or expose this medication to high heat or open flame. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

              MEDICAL ALERT: Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-888-633-4298 (US) or 1-800-668-1507 (Canada).

              Information last revised March 2023. Copyright(c) 2023 First Databank, Inc.

              IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

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              Formulary

              FormularyPatient Discounts

              Adding plans allows you to compare formulary status to other drugs in the same class.

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              The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

              Tier Description
              1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
              2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
              3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
              4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
              5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
              6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
              NC NOT COVERED – Drugs that are not covered by the plan.
              Code Definition
              PA Prior Authorization
              Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
              QL Quantity Limits
              Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
              ST Step Therapy
              Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
              OR Other Restrictions
              Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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              Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.