Dosing & Uses
Multiple Myeloma
Pending FDA approval for relapses or refractory multiple myeloma
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Pharmacology
Mechanism of Action
Antibody that binds to both CD3 on T-cell and B-cell maturation antigen (BCMA), which is expressed on the surface of multiple myeloma cells
This results in cross-linking of T-cells and myeloma cells, and induces a potent cytotoxic T-lymphocyte response against BCMA-expressing cells
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Images
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
