Tongkat Ali (Herb/Suppl)

Brand and Other Names:eurycoma longifolia, longjack, more...pasak bumi, tung saw
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Suggested Dosing

Check Mfr's instructions

Extract (100:1): 25 mg PO q2-3day recommended by one Mfr

Full-spectrum Powder: 200 mg PO qD or 400 mg PO qOD

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Suggested Uses

Enhancement of male sexual function

Also has been used as antimalarial

Efficacy

Animal studies show some positive results for male sexual function enhancement; no human clinical trials

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Interactions

Interaction Checker

and Tongkat Ali

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (26)

              • adalimumab

                adalimumab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • alefacept

                alefacept and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • anakinra

                anakinra and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • antithymocyte globulin equine

                antithymocyte globulin equine and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • antithymocyte globulin rabbit

                antithymocyte globulin rabbit and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • azathioprine

                azathioprine and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • basiliximab

                basiliximab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • canakinumab

                canakinumab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • cyclosporine

                cyclosporine and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • etanercept

                etanercept and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • everolimus

                everolimus and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • glatiramer

                glatiramer and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • golimumab

                golimumab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • hydroxychloroquine sulfate

                hydroxychloroquine sulfate and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • infliximab

                infliximab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • leflunomide

                leflunomide and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • mercaptopurine

                mercaptopurine and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • methotrexate

                methotrexate and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • muromonab CD3

                muromonab CD3 and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • mycophenolate

                mycophenolate and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • rilonacept

                rilonacept and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • sirolimus

                sirolimus and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • tacrolimus

                tacrolimus and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • temsirolimus

                temsirolimus and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • tocilizumab

                tocilizumab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • ustekinumab

                ustekinumab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              Monitor Closely (3)

              • astragalus

                tongkat ali increases and astragalus decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • echinacea

                tongkat ali increases and echinacea decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              • maitake

                tongkat ali increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

              Minor (23)

              • acarbose

                tongkat ali increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • chlorpropamide

                tongkat ali increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • glimepiride

                tongkat ali increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • glipizide

                tongkat ali increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • glyburide

                tongkat ali increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • insulin aspart

                tongkat ali increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • insulin detemir

                tongkat ali increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • insulin glargine

                tongkat ali increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • insulin glulisine

                tongkat ali increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • insulin lispro

                tongkat ali increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • insulin NPH

                tongkat ali increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • insulin regular human

                tongkat ali increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • metformin

                tongkat ali increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • miglitol

                tongkat ali increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • nateglinide

                tongkat ali increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • pioglitazone

                tongkat ali increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • repaglinide

                tongkat ali increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • rosiglitazone

                tongkat ali increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • saxagliptin

                tongkat ali increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • sitagliptin

                tongkat ali increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • tolazamide

                tongkat ali increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • tolbutamide

                tongkat ali increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

              • vildagliptin

                tongkat ali increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

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              Adverse Effects

              Insomnia, irritability, restlessness

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              Warnings

              Contraindications

              Prostate cancer, male breast cancer, DM, heart disease, sleep apnea, kidney disease

              Concomitant immunosuppressants

              Cautions

              May decrease blood glucose levels

              May cause severe insomnia esp in high doses

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              Pregnancy & Lactation

              Pregnancy Category: avoid

              Lactation: avoid

              Pregnancy Categories

              A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

              B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

              C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

              D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

              X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

              NA: Information not available.

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              Pharmacology

              Metabolism: N/A

              Excretion: N/A

              Mechanism of Action

              Apparently increases testosterone levels

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              Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.