Indication-specific dosing for eurycoma longifolia, longjack, pasak bumi, tung saw (tongkat ali), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.

Sections

Sections Tongkat Ali
Suggested Dosing
Suggested Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology

Suggested Dosing

Check Mfr's instructions

Extract (100:1): 25 mg PO q2-3day recommended by one Mfr

Full-spectrum Powder: 200 mg PO qD or 400 mg PO qOD

Suggested Uses

Enhancement of male sexual function

Also has been used as antimalarial

Efficacy

Animal studies show some positive results for male sexual function enhancement; no human clinical trials

Interaction Checker

Enter a drug name and Tongkat Ali

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No Interactions Found

Interactions Found

Contraindicated

Serious - Use Alternative

Significant - Monitor Closely

Minor

All Interactions Sort By:

Contraindicated (0)

Serious - Use Alternative (26)

adalimumab
adalimumab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
alefacept
alefacept and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
anakinra
anakinra and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
antithymocyte globulin equine
antithymocyte globulin equine and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
antithymocyte globulin rabbit
antithymocyte globulin rabbit and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
azathioprine
azathioprine and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
basiliximab
basiliximab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
canakinumab
canakinumab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
cyclosporine
cyclosporine and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
etanercept
etanercept and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
everolimus
everolimus and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
glatiramer
glatiramer and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
golimumab
golimumab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
hydroxychloroquine sulfate
hydroxychloroquine sulfate and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
infliximab
infliximab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
leflunomide
leflunomide and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
mercaptopurine
mercaptopurine and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
methotrexate
methotrexate and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
muromonab CD3
muromonab CD3 and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
mycophenolate
mycophenolate and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
rilonacept
rilonacept and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
sirolimus
sirolimus and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
tacrolimus
tacrolimus and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
temsirolimus
temsirolimus and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
tocilizumab
tocilizumab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
ustekinumab
ustekinumab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

Monitor Closely (3)

astragalus
tongkat ali increases and astragalus decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.
echinacea
tongkat ali increases and echinacea decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.
maitake
tongkat ali increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

Minor (23)

acarbose
tongkat ali increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
chlorpropamide
tongkat ali increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
glimepiride
tongkat ali increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
glipizide
tongkat ali increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
glyburide
tongkat ali increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
insulin aspart
tongkat ali increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
insulin detemir
tongkat ali increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
insulin glargine
tongkat ali increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
insulin glulisine
tongkat ali increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
insulin lispro
tongkat ali increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
insulin NPH
tongkat ali increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
insulin regular human
tongkat ali increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
metformin
tongkat ali increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
miglitol
tongkat ali increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
nateglinide
tongkat ali increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
pioglitazone
tongkat ali increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
repaglinide
tongkat ali increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
rosiglitazone
tongkat ali increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
saxagliptin
tongkat ali increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
sitagliptin
tongkat ali increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
tolazamide
tongkat ali increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
tolbutamide
tongkat ali increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
vildagliptin
tongkat ali increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

acarbose
Minor (1)tongkat ali increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
adalimumab
Serious - Use Alternative (1)adalimumab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
alefacept
Serious - Use Alternative (1)alefacept and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
anakinra
Serious - Use Alternative (1)anakinra and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
antithymocyte globulin equine
Serious - Use Alternative (1)antithymocyte globulin equine and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
antithymocyte globulin rabbit
Serious - Use Alternative (1)antithymocyte globulin rabbit and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
astragalus
Monitor Closely (1)tongkat ali increases and astragalus decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.
azathioprine
Serious - Use Alternative (1)azathioprine and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
basiliximab
Serious - Use Alternative (1)basiliximab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
canakinumab
Serious - Use Alternative (1)canakinumab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
chlorpropamide
Minor (1)tongkat ali increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
cyclosporine
Serious - Use Alternative (1)cyclosporine and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
echinacea
Monitor Closely (1)tongkat ali increases and echinacea decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.
etanercept
Serious - Use Alternative (1)etanercept and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
everolimus
Serious - Use Alternative (1)everolimus and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
glatiramer
Serious - Use Alternative (1)glatiramer and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
glimepiride
Minor (1)tongkat ali increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
glipizide
Minor (1)tongkat ali increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
glyburide
Minor (1)tongkat ali increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
golimumab
Serious - Use Alternative (1)golimumab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
hydroxychloroquine sulfate
Serious - Use Alternative (1)hydroxychloroquine sulfate and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
infliximab
Serious - Use Alternative (1)infliximab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
insulin aspart
Minor (1)tongkat ali increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
insulin detemir
Minor (1)tongkat ali increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
insulin glargine
Minor (1)tongkat ali increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
insulin glulisine
Minor (1)tongkat ali increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
insulin lispro
Minor (1)tongkat ali increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
insulin NPH
Minor (1)tongkat ali increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
insulin regular human
Minor (1)tongkat ali increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
leflunomide
Serious - Use Alternative (1)leflunomide and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
maitake
Monitor Closely (1)tongkat ali increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.
mercaptopurine
Serious - Use Alternative (1)mercaptopurine and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
metformin
Minor (1)tongkat ali increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
methotrexate
Serious - Use Alternative (1)methotrexate and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
miglitol
Minor (1)tongkat ali increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
muromonab CD3
Serious - Use Alternative (1)muromonab CD3 and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
mycophenolate
Serious - Use Alternative (1)mycophenolate and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
nateglinide
Minor (1)tongkat ali increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
pioglitazone
Minor (1)tongkat ali increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
repaglinide
Minor (1)tongkat ali increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
rilonacept
Serious - Use Alternative (1)rilonacept and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
rosiglitazone
Minor (1)tongkat ali increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
saxagliptin
Minor (1)tongkat ali increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
sirolimus
Serious - Use Alternative (1)sirolimus and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
sitagliptin
Minor (1)tongkat ali increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
tacrolimus
Serious - Use Alternative (1)tacrolimus and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
temsirolimus
Serious - Use Alternative (1)temsirolimus and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
tocilizumab
Serious - Use Alternative (1)tocilizumab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
tolazamide
Minor (1)tongkat ali increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
tolbutamide
Minor (1)tongkat ali increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.
ustekinumab
Serious - Use Alternative (1)ustekinumab and tongkat ali both increase immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.
vildagliptin
Minor (1)tongkat ali increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia.

Adverse Effects

Insomnia, irritability, restlessness

Contraindications

Prostate cancer, male breast cancer, DM, heart disease, sleep apnea, kidney disease

Concomitant immunosuppressants

Cautions

May decrease blood glucose levels

May cause severe insomnia esp in high doses

Pregnancy & Lactation

Pregnancy Category: avoid

Lactation: avoid

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Pharmacology

Metabolism: N/A

Excretion: N/A

Mechanism of Action

Apparently increases testosterone levels

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

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Sections Tongkat Ali
Suggested Dosing
Suggested Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology

Tongkat Ali (Herb/Suppl)