fibrin sealant (Rx)

Adjunct to Hemostasis

Follow Mfr's instructions for reconstitution and application

Evicel

• Indicated as an adjunct to hemostasis for use in patients undergoing surgery, when control of bleeding by standard surgical techniques (eg, suture, ligature, cautery) is ineffective or impractical
• Spray or drop onto surface of bleeding tissues in short bursts (0.1-0.2 mL); if hemostatic effect not complete, apply a second layer; if maximum area to be sealed is 20 cm² use 2 mL; if area to be sealed is
• If maximum area to be sealsed is 20 cm² use 2 mL
• If maximum area to be sealed is 40 cm² use 4 mL
• If maximum area to be sealed 100 cm² use 10 mL

TachoSil Patch

• Suppportive treatment in surgery for imporvement of haemostasis, to promote tissue sealing, and for suture support in vascular surgery where standard techniques are insufficient
• If maximum patches to be applied is 7 apply patch size 9.5 cm x 4.8 cm
• If maximum patches to be applied is 14 apply patch size 4.8 cm x 4.8 cm
• If maximum patches to be applied is 42 apply patch size 3.0 cm x 2.5 cm

Tisseel VH

• Hemostasis: indicated for use as an adjunct to hemostasis in surgeries involving cardiopulmonary bypass and treatment of blunt or penetrating splenic injuries when control of bleeding by conventional surgical techniques (eg, suture, ligature, cautery) is ineffective or impractical
• May be used in fully heparinized patients undergoing cardiopulmonar y bypass
• Sealing: Indicated as an adjunct to standard surgical techniques (eg, suture, ligature) to prevent leakage from colonic anastomoses following the reversal of temporary colostomies
• If maximum area to be sealsed is 8 cm² via cannula or 100 cm² using spray, use 2 mL
• If maximum area to be sealed is 16 cm² via cannula or 200 cm² using spray, use 4 mL
• If maximum area to be sealed 40 cm² via cannula or 500 cm² using spray, use 10 mL

Autologous Skin Graft Adherence

Artiss

• Indicated to adhere autologous skin grafts to surgically prepared wound beds resulting from burns in adult and pediatric populations greater than or equal to1 year of age
• Adhering tissue flaps during facial rhytidectomy surgery (face-lift)
• Not indicated as an adjunct to hemostasis
• If graft fixation area is 100 cm² use 2 mL
• If graft fixation area is 200 cm² use 4 mL
• If graft fixation area is 500 cm² use 10 mL

Tissue Flap Adherence in Facelift

Artiss

• Spray topically in an even thin layer over the wound bed immediately prior to attaching skin flap
• If graft fixation area is 100 cm² use 2 mL
• If graft fixation area is 200 cm² use 4 mL
• If graft fixation area is 500 cm² use 10 mL

Adjunct to Hemostasis

Indicated as an adjunct to hemostasis for use in patients undergoing surgery, when control of bleeding by standard surgical techniques (eg, suture, ligature, cautery) is ineffective or impractical

Follow Mfr's instructions for reconstitution and application

Evicel

• <6 months: Safety and efficacy not established
• ≥6 months: Spray or drop onto surface of bleeding tissues in short bursts (0.1-0.2 mL); if hemostatic effect not complete, apply a second layer; if maximum area to be sealed is 20 cm² use 2 mL

• If area to be sealed is

  • If maximum area to be sealed is 20 cm² use 2 mL
  • If maximum area to be sealed is 40 cm² use 4 mL
  • If maximum area to be sealed 100 cm² use 10 mL

Tisseel

• Also indicated as an adjunct to standard surgical techniques (such as suture and ligature) to prevent leakage from colonic anastomoses following the reversal of temporary colostomies
• <1 month: Safety and efficacy not established

• ≥1 month

  • If maximum area to be sealed is 8 cm² via cannula or 100 cm² using spray;, use 2 mL
  • If maximum area to be sealed is 16 cm² via cannula or 200 cm² using spray, use 4 mL
  • If maximum area to be sealed 40 cm² via cannula or 500 cm² using spray, use 10 mL

Autologous Skin Graft Adherence

Artiss

• <1 year: Safety and efficacy not established

• Indications

  • Indicated to adhere autologous skin grafts to surgically prepared wound beds resulting from burns in adult and pediatric populations greater than or equal to1 year of age
  • Adhering tissue flaps during facial rhytidectomy surgery (face-lift)
  • Not indicated as an adjunct to hemostasis

• Graft fixation area

  • If graft fixation area is 100 cm² use 2 mL
  • If graft fixation area is 200 cm² use 4 mL
  • If graft fixation area is 500 cm² use 10 mL