carbonyl iron (Rx, OTC)

Brand and Other Names:Feosol (Carbonyl Fe), Icar C, more...Icar Pediatric, Ircon
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Dosing & Uses

AdultPediatricGeriatric

Dosage Forms & Strengths

tablet

  • 45mg (Feosol)
  • 66mg (Ircon)

oral suspension

  • 15mg/1.25mL (Icar Pediatric)

tablet, chewable

  • 15mg (Icar Pediatric, Wee Care)

tablet with vitamin C

  • 100mg iron/250mg vitamin C (Icar C)
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Dietary Iron Supplement

Doses expressed as elemental iron unless otherwise noted

19-50 years old:

Male: 8 mg PO qDay

Female: 18 mg PO qDay

Pregnant female: 27 mg PO qDay

Lactating female 9 mg PO qDay

>50 years old: 8 mg PO qDay

Iron Deficiency Anemia

300 mg PO q12hr; may increase to 300 mg q6hr or 250 mg ER PO q12hr

Note: Dose expressed as ferrous sulfate

Prophylaxis of Iron Deficiency

300 mg PO qDay

Note: Dose expressed as ferrous sulfate

Dosage Forms & Strengths

tablet

  • 45mg (Feosol)
  • 66mg (Ircon)

oral suspension

  • 15mg/1.25mL (Icar Pediatric)

tablet, chewable

  • 15mg (Icar Pediatric)

tablet with vitamin C

  • 100mg iron/250mg vitamin C (Icar C)
more...

Dietary Iron Supplement

Doses expressed elemental iron unless otherwise noted

0-6 months old: 0.27 mg PO qDay (adequate intake)

7-12 months old: 11 mg PO qDay

1-3 years old: 7 mg PO qDay

3-8 years old: 10 mg PO qDay

8-12 years old: 8 mg PO qDay

>12 years old: Same as adult

Severe Iron Deficiency Anemia

4-6 mg/kg PO divided q8hr 

Mild to Moderate Iron Deficiency Anemia

3 mg/kg PO qDay or divided q12hr 

Prophylaxis

1-2 mg/kg PO; 15 mg PO maximum 

Lower doses of 10-50 mg elemental iron/day recommended may cause fewer GI adverse ements

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Interactions

Interaction Checker

and carbonyl iron

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            >10%

            Constipation

            Diarrhea

            Nausea

            Epigastric pain

            Dark stools

            Vomiting

            Dark stools

            Frequency Not Defined

            Hemosiderosis (during long-term administration of large amounts)

            Urine discoloration

            Dental stain by some formulations

            Heartburn

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            Warnings

            Black Box Warnings

            Severe iron toxicity may occur in overdose, especially when ingested by children.  

            Nonintentional iron overdose is the leading cause of fatal poisoning in children younger than 6 years. Keep out of reach of children

            Contraindications

            Hypersensitivity

            Hemochromatosis, hemolytic anemia or anemia not associated with iron deficiency

            Peptic ulcer, regional enteritis, ulcerative colitis

            Cautions

            Do not take within 2 hr of oral tetracycline antibiotics

            Not for use in patients receiving frequent blood transfusions

            Avoid in premature infants until their deficient vitamin E stores at birth are replenished

            Avoid administering iron for >6 months except in patients with continuous bleeding or menorrhagia

            May cause increased red cell hemolysis & hemolytic anemia in infants with low serum vitamin E concentrations

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            Pregnancy & Lactation

            Pregnancy Category: Not available

            Lactation: Excreted in breast milk

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Mechanism of Action

            Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin

            Pharmacokinetics

            Onset: 3-10 days (reticulocytosis); 2-4 weeks (hemoglobin values increase)

            Absorption: 5-13% (20-30% during deficiency)

            Excretion: Sweat, urine, menses, sloughing of intestinal mucosa

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            Administration

            Oral Administration

            For maximum absorption take on empty stomach, but may take with or after meals to minimize GI irritation

            Some formulations contain vitamin C; vitamin C may enhance absorption

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            Images

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            Formulary

            FormularyPatient Discounts

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            The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

            Tier Description
            1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
            2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
            3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
            4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            NC NOT COVERED – Drugs that are not covered by the plan.
            Code Definition
            PA Prior Authorization
            Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
            QL Quantity Limits
            Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
            ST Step Therapy
            Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
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            Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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            Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.