cefiderocol (Pending FDA Approval)

Brand and Other Names:Fetroja
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Dosing & Uses

Urinary Tract Infection

Pending FDA approval for treatment of complicated urinary tract infections

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Pharmacology

Mechanism of Action

Siderophore (ie, iron-chelating) cephalosporin with activity against highly resistant Gram-negative bacterial including carbapenem-resistant strains of Enterobacteriaceae and nonfermenting bacteria

Its mechanism is described as a “Trojan-horse antibiotic”, because of the method by which cefiderocol enters bacterial cells by binding to iron that is actively transported into the cell

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.