Dosing & Uses
Menopausal Vasomotor Symptoms
Pending FDA approval for moderate-to-severe vasomotor symptoms (VMS) associated with menopause
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Pharmacology
Mechanism of Action
Nonhormonal selective neurokinin 3 (NK3) receptor antagonist
Blocks neurokinin B (NKB) binding on the kisspeptin/neurokinin/dynorphin (KNDy) neuron to moderate neuronal activity in the hypothalamus, and thereby reduces frequency and severity of vasomotor symptoms
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Images
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
