Dosing & Uses
Dosage Forms & Strengths
tablet
- 625mg
tablet, chewable
- 625mg
Constipation
1250 mg with 8 oz of water PO qday to q6hr; not to exceed 6 g/day
Dosage Forms & Strengths
tablet
- 625mg
tablet, chewable
- 625mg
Constipation
<6 years: Administer under physician supervision; 625 mg with 8 oz of water PO qDay or q12hr; not to exceed 1.25 g/day
>6-12 years: Swallow 1 tab qDay or q6hr
>12 years: 1250 mg with 8 oz of water PO q6hr; not to exceed 6 g/day
Constipation
1250 mg with 8 oz of water PO qday to q6hr; not to exceed 6 g/day
Interactions
Interaction Checker
No Results
Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor
Contraindicated (0)
Serious - Use Alternative (0)
Monitor Closely (5)
- demeclocycline
polycarbophil decreases levels of demeclocycline by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.
- doxycycline
polycarbophil decreases levels of doxycycline by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.
- minocycline
polycarbophil decreases levels of minocycline by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.
- oxytetracycline
polycarbophil decreases levels of oxytetracycline by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.
- tetracycline
polycarbophil decreases levels of tetracycline by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.
Minor (1)
- sodium picosulfate
polycarbophil decreases effects of sodium picosulfate by Mechanism: unspecified interaction mechanism. Minor/Significance Unknown.
Adverse Effects
Frequency Not Defined
Abdominal fullness
Flatulence
Vomiting
Stomach cramps
Warnings
Contraindications
Hypersensitivity
Bowel obstruction, appendicitis, dysphagia, fecal impaction, rectal bleeding
Cautions
Taking this product without adequate fluid may cause it to swell and block your throat or esophagus and may cause choking; do not take this product if you have difficulty in swallowing; if experience chest pain, vomiting, or difficulty in swallowing or breathing after taking this product, seek immediate medical attention
Ask a physician before using this product if experiencing abdominal pain, nausea or vomiting, sudden change in bowel habits that lasts over a period of 2 weeks
Ask a healthcare professional if taking any other drug; take the product 2 or more hours before or after other drugs; laxatives may affect how other drugs work
Not for use longer than 7 days unless directed by a physician
Stop use and ask a physician if rectal bleeding occurs or if fail to have a bowel movement after use of this or other laxative; it could be a sign of serious condition
Keep out of reach of children; if overdose, get medical help or contact poison control center right away
Pregnancy & Lactation
Pregnancy Category: NA; not absorbed; safe to be administered in pregnancy
Lactation: No data in nursing women; not absorbed and should be safe to use in nursing women
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Bulk producing laxative that restores normal moisture level
Pharmacokinetics
Absorption: Minimal systemic absorption
Onset: 12-72 hr
Metabolism: Metabolically inert
Excretion: Feces
