fenfluramine (Pending FDA Approval)

Brand and Other Names:Fintepla
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Dosing & Uses

AdultPediatric

Epilepsy

Pending FDA approval for pharmaco-resistant epilepsies (eg, Dravet syndrome)

Epilepsy

Pending FDA approval for pharmaco-resistant epilepsies (eg, Dravet syndrome)

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Pharmacology

Mechanism of Action

The mechanism by which fenfluramine elicits antiseizure effects is not fully understood

It is an indirect-acting sympathomimetic; stimulates serotonin release and inhibits its reuptake resulting in increased CNS serotonin concentrations

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.