Dosing & Uses
Dosage Forms & Strengths
enema
- 118mL
Constipation/Fecal Impaction
Contents of 1 bottle (ie, 118 mL) rectally as a single dose
May also be used following barium studies
Administration
Patient should lie on left side with right knee bent
Gently insert enema tip into rectum using slight side-to-side movement; point enema tip toward navel (ease insertion by having patient bear down, as if having a bowel movement, to relax anal muscles)
Do not force enema tip into rectum
Squeeze bottle to deliver all contents in bottle
Remove enema tip from rectum
Retain enema in accordance with doctor's instructions
If stool remains that is not softened or lubricated, use cleansing enema
Dosage Forms & Strengths
enema
- 118mL
Constipation/Fecal Impaction
<1 year: Safety & efficacy not established
2-12 years: One-half bottle (ie, 59 mL) rectally as a single dose
>12 years: As adults; contents of 1 bottle (ie, 118 mL) rectally as a single dose
Administration
Patient should lie on left side with right knee bent
Gently insert enema tip into rectum using slight side-to-side movement; point enema tip toward navel (ease insertion by having patient bear down, as if having a bowel movement, to relax anal muscles)
Do not force enema tip into rectum
Squeeze bottle to deliver appropriate dose
Remove enema tip from rectum
Retain enema in accordance with doctor's instructions
If stool remains that is not softened or lubricated, use cleansing enema
Adverse Effects
Frequency Not Defined
Anal seepage
Pruritus ani
Perianal discomfort
Warnings
Contraindications
Hypersensitivity
Patients with colostomy, ileostomy, appendicitis, ulcerative colitis, or diverticulitis
<13 years
Bedridden patients
Presently taking stool softener laxative
Cautions
For rectal use only
Excessive use may cause electrolyte imbalance, steatorrhea, osteomalacia, diarrhea, & cathartic colon
Ask healthcare professional if already used laxative for >3 days, experiencing abdominal pain, nausea, or vomiting, or experienced sudden bowel habits that persist over period of 2 weeks
To be taken only at bedtime; do not use at any other time or administer to infants, except upon advice of a physician
Discontinue use and talk to healthcare professional if experience bleeding after use or fail to have bowel movement within 30 minutes of enema use
Keep out of reach of children; if swallowed, get medical help or contact a Poison Control Center right away (800-222-1222)
Pregnancy & Lactation
Pregnancy
Ask healthcare professional
Lactation
Ask healthcare professional
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Emollient; softens stool in colon by retarding colonic absorption of fecal water