Saccharomyces Boulardii (OTC)

Brand and Other Names:Florastor, Florastor Kids, more...S. boulardii, Saccharomyces boulardii lyo
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Suggested Dosing

1 capsule/packet PO BID

Administration

May swallow capsule whole, or empty contents of capsule or packet onto tongue followed by drinking 4 oz of water or juice

May also open capsule or packet and sprinkle over semisolid food (eg, applesauce, yogurt)

Additionally, may open capsule or packet and dissolve contents in liquid and drink (eg, water, juice, milk)

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Suggested Uses

Intestinal Flora Restoration

Restoration of intestinal flora, post-antibiotic diarrhea and prevention of post-antibiotic vulvovaginal candidiasis

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Interactions

Interaction Checker

and Saccharomyces Boulardii

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            All Interactions Sort By:
             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (16)

              • amphotericin B cholesteryl sulfate

                amphotericin B cholesteryl sulfate decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.

              • amphotericin B deoxycholate

                amphotericin B deoxycholate decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.

              • amphotericin B liposomal

                amphotericin B liposomal decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.

              • amphotericin B phospholipid complex

                amphotericin B phospholipid complex decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.

              • anidulafungin

                anidulafungin decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.

              • caspofungin

                caspofungin decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.

              • fluconazole

                fluconazole decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.

              • flucytosine

                flucytosine decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.

              • griseofulvin

                griseofulvin decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.

              • itraconazole

                itraconazole decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.

              • ketoconazole

                ketoconazole decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.

              • micafungin

                micafungin decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.

              • nystatin

                nystatin decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.

              • posaconazole

                posaconazole decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.

              • terbinafine

                terbinafine decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.

              • voriconazole

                voriconazole decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.

              Monitor Closely (0)

                Minor (0)

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                  Adverse Effects

                  N/A

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                  Warnings

                  Contraindications

                  Patients with a central line

                  Yeast allergy

                  Hypersensitivity to product or excipients

                  Cautions

                  Use with caution in patients with lactose intolerance; some products may contain lactose

                  Use with caution in immunocompromised patients as product contains live bacteria; fungemia reported in premature infants

                  Do not open packets or capsules when in the vicinity of patients with central lines; change gloves after handling product to avoid transfer into central lines of patients

                  Dietary supplements do not have safety or efficacy review by the FDA; conclusive evidence to support widespread use of product in the treatment of diarrhea is lacking

                  Potentially significant interactions possible; frequency, dose adjustment, or monitoring may be necessary

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                  Pregnancy & Lactation

                  Pregnancy Category: N/A

                  Lactation: Unknown if excreted into breast milk

                  Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

                  Pregnancy Categories

                  A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                  B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                  C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                  D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                  X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                  NA: Information not available.

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                  Pharmacology

                  Mechanism of Action

                  Restores normal bowel flora that inhibit growth of harmful bacteria; stimulates local immunity; promotes water reabsorption in colon

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                  Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.