Suggested Dosing
1 capsule/packet PO BID
Administration
May swallow capsule whole, or empty contents of capsule or packet onto tongue followed by drinking 4 oz of water or juice
May also open capsule or packet and sprinkle over semisolid food (eg, applesauce, yogurt)
Additionally, may open capsule or packet and dissolve contents in liquid and drink (eg, water, juice, milk)
Suggested Uses
Intestinal Flora Restoration
Restoration of intestinal flora, post-antibiotic diarrhea and prevention of post-antibiotic vulvovaginal candidiasis
Interactions
Interaction Checker
No Results
Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor
Contraindicated (0)
Serious - Use Alternative (17)
- amphotericin B cholesteryl sulfate
amphotericin B cholesteryl sulfate decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
- amphotericin B deoxycholate
amphotericin B deoxycholate decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
- amphotericin B liposomal
amphotericin B liposomal decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
- amphotericin B phospholipid complex
amphotericin B phospholipid complex decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
- anidulafungin
anidulafungin decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
- caspofungin
caspofungin decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
- fluconazole
fluconazole decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
- flucytosine
flucytosine decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
- griseofulvin
griseofulvin decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
- itraconazole
itraconazole decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
- ketoconazole
ketoconazole decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
- levoketoconazole
levoketoconazole decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
- micafungin
micafungin decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
- nystatin
nystatin decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
- posaconazole
posaconazole decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
- terbinafine
terbinafine decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
- voriconazole
voriconazole decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
Monitor Closely (0)
Minor (0)
Adverse Effects
N/A
Warnings
Contraindications
Patients with a central line
Yeast allergy
Hypersensitivity to product or excipients
Cautions
Use with caution in patients with lactose intolerance; some products may contain lactose
Use with caution in immunocompromised patients as product contains live bacteria; fungemia reported in premature infants
Do not open packets or capsules when in the vicinity of patients with central lines; change gloves after handling product to avoid transfer into central lines of patients
Dietary supplements do not have safety or efficacy review by the FDA; conclusive evidence to support widespread use of product in the treatment of diarrhea is lacking
Potentially significant interactions possible; frequency, dose adjustment, or monitoring may be necessary
Pregnancy & Lactation
Pregnancy Category: N/A
Lactation: Unknown if excreted into breast milk
Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Restores normal bowel flora that inhibit growth of harmful bacteria; stimulates local immunity; promotes water reabsorption in colon
