Indication-specific dosing for ganoderma lucidum, ling chih (reishi), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.

Sections

Sections Reishi
Suggested Dosing
Suggested Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology

Suggested Dosing

Dried mushroom: 1.5-9 g/d PO

Powder: 1-1.5 g/d PO

Tincture: 1 mL/d PO

Suggested Uses

To reduce high blood pressure, hypertriglyceridemia

Treatment of postherpetic neuralgia.

Supportive treatment during cancer chemotherapy

Efficacy:

Active ingredients, called ganoderic acids, appear to combat high BP & reduce LDL cholesterol & triglyceride levels; may also discourage platelet aggregation

Also contains antiangiogenic & other antimetastatic substances

Interaction Checker

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Contraindicated

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Minor

All Interactions Sort By:

Contraindicated (0)

Serious - Use Alternative (0)

Monitor Closely (69)

aceclofenac
aceclofenac and reishi both increase anticoagulation. Use Caution/Monitor.
acemetacin
acemetacin and reishi both increase anticoagulation. Use Caution/Monitor.
agrimony
agrimony and reishi both increase anticoagulation. Use Caution/Monitor.
alfalfa
alfalfa and reishi both increase anticoagulation. Use Caution/Monitor.
alteplase
alteplase and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
American ginseng
American ginseng and reishi both increase anticoagulation. Use Caution/Monitor.
antithrombin alfa
antithrombin alfa and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
antithrombin III
antithrombin III and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
argatroban
argatroban and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
aspirin
aspirin and reishi both increase anticoagulation. Use Caution/Monitor.
aspirin rectal
aspirin rectal and reishi both increase anticoagulation. Use Caution/Monitor.
aspirin/citric acid/sodium bicarbonate
aspirin/citric acid/sodium bicarbonate and reishi both increase anticoagulation. Use Caution/Monitor.
bemiparin
bemiparin and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
bivalirudin
bivalirudin and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
celecoxib
celecoxib and reishi both increase anticoagulation. Use Caution/Monitor.
choline magnesium trisalicylate
choline magnesium trisalicylate and reishi both increase anticoagulation. Use Caution/Monitor.
cinnamon
cinnamon and reishi both increase anticoagulation. Use Caution/Monitor.
cordyceps
cordyceps and reishi both increase anticoagulation. Use Caution/Monitor.
dabigatran
dabigatran and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
dalteparin
dalteparin and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
diclofenac
diclofenac and reishi both increase anticoagulation. Use Caution/Monitor.
diflunisal
diflunisal and reishi both increase anticoagulation. Use Caution/Monitor.
dong quai
dong quai and reishi both increase anticoagulation. Use Caution/Monitor.
enoxaparin
enoxaparin and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
epoprostenol
epoprostenol and reishi both increase anticoagulation. Use Caution/Monitor.
etodolac
etodolac and reishi both increase anticoagulation. Use Caution/Monitor.
fennel
fennel and reishi both increase anticoagulation. Use Caution/Monitor.
fenoprofen
fenoprofen and reishi both increase anticoagulation. Use Caution/Monitor.
feverfew
feverfew and reishi both increase anticoagulation. Use Caution/Monitor.
flurbiprofen
flurbiprofen and reishi both increase anticoagulation. Use Caution/Monitor.
fondaparinux
fondaparinux and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
forskolin
forskolin and reishi both increase anticoagulation. Use Caution/Monitor.
garlic
garlic and reishi both increase anticoagulation. Use Caution/Monitor.
ginger
ginger and reishi both increase anticoagulation. Use Caution/Monitor.
ginkgo biloba
ginkgo biloba and reishi both increase anticoagulation. Use Caution/Monitor.
heparin
heparin and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
horse chestnut seed
horse chestnut seed and reishi both increase anticoagulation. Use Caution/Monitor.
ibuprofen
ibuprofen and reishi both increase anticoagulation. Use Caution/Monitor.
ibuprofen IV
ibuprofen IV and reishi both increase anticoagulation. Use Caution/Monitor.
indomethacin
indomethacin and reishi both increase anticoagulation. Use Caution/Monitor.
ketoprofen
ketoprofen and reishi both increase anticoagulation. Use Caution/Monitor.
ketorolac
ketorolac and reishi both increase anticoagulation. Use Caution/Monitor.
ketorolac intranasal
ketorolac intranasal and reishi both increase anticoagulation. Use Caution/Monitor.
lornoxicam
lornoxicam and reishi both increase anticoagulation. Use Caution/Monitor.
meclofenamate
meclofenamate and reishi both increase anticoagulation. Use Caution/Monitor.
mefenamic acid
mefenamic acid and reishi both increase anticoagulation. Use Caution/Monitor.
meloxicam
meloxicam and reishi both increase anticoagulation. Use Caution/Monitor.
mistletoe
reishi increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.
nabumetone
nabumetone and reishi both increase anticoagulation. Use Caution/Monitor.
naproxen
naproxen and reishi both increase anticoagulation. Use Caution/Monitor.
nettle
reishi increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.
oxaprozin
oxaprozin and reishi both increase anticoagulation. Use Caution/Monitor.
panax ginseng
panax ginseng and reishi both increase anticoagulation. Use Caution/Monitor.
parecoxib
parecoxib and reishi both increase anticoagulation. Use Caution/Monitor.
pau d'arco
pau d'arco and reishi both increase anticoagulation. Use Caution/Monitor.
phenindione
phenindione and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
phytoestrogens
phytoestrogens and reishi both increase anticoagulation. Use Caution/Monitor.
piroxicam
piroxicam and reishi both increase anticoagulation. Use Caution/Monitor.
protamine
protamine and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
reteplase
reteplase and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
salicylates (non-asa)
salicylates (non-asa) and reishi both increase anticoagulation. Use Caution/Monitor.
salsalate
salsalate and reishi both increase anticoagulation. Use Caution/Monitor.
Siberian ginseng
reishi and Siberian ginseng both increase anticoagulation. Use Caution/Monitor.
sulfasalazine
sulfasalazine and reishi both increase anticoagulation. Use Caution/Monitor.
sulindac
sulindac and reishi both increase anticoagulation. Use Caution/Monitor.
tenecteplase
tenecteplase and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
tolfenamic acid
tolfenamic acid and reishi both increase anticoagulation. Use Caution/Monitor.
tolmetin
tolmetin and reishi both increase anticoagulation. Use Caution/Monitor.
vitamin K1 (phytonadione)
reishi increases and vitamin K1 (phytonadione) decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

Minor (77)

acebutolol
reishi increases effects of acebutolol by pharmacodynamic synergism. Minor/Significance Unknown.
amiloride
reishi increases effects of amiloride by pharmacodynamic synergism. Minor/Significance Unknown.
amlodipine
reishi increases effects of amlodipine by pharmacodynamic synergism. Minor/Significance Unknown.
anamu
anamu and reishi both increase anticoagulation. Minor/Significance Unknown.
atenolol
reishi increases effects of atenolol by pharmacodynamic synergism. Minor/Significance Unknown.
benazepril
reishi increases effects of benazepril by pharmacodynamic synergism. Minor/Significance Unknown. Enhanced hypotensive and hypoglycemic effects.
bendroflumethiazide
reishi increases effects of bendroflumethiazide by pharmacodynamic synergism. Minor/Significance Unknown.
betaxolol
reishi increases effects of betaxolol by pharmacodynamic synergism. Minor/Significance Unknown.
bisoprolol
reishi increases effects of bisoprolol by pharmacodynamic synergism. Minor/Significance Unknown.
bosentan
reishi increases effects of bosentan by pharmacodynamic synergism. Minor/Significance Unknown.
bumetanide
reishi increases effects of bumetanide by pharmacodynamic synergism. Minor/Significance Unknown.
candesartan
reishi increases effects of candesartan by pharmacodynamic synergism. Minor/Significance Unknown.
captopril
reishi increases effects of captopril by pharmacodynamic synergism. Minor/Significance Unknown.
carvedilol
reishi increases effects of carvedilol by pharmacodynamic synergism. Minor/Significance Unknown.
celiprolol
reishi increases effects of celiprolol by pharmacodynamic synergism. Minor/Significance Unknown.
chlorothiazide
reishi increases effects of chlorothiazide by pharmacodynamic synergism. Minor/Significance Unknown.
chlorthalidone
reishi increases effects of chlorthalidone by pharmacodynamic synergism. Minor/Significance Unknown.
clevidipine
reishi increases effects of clevidipine by pharmacodynamic synergism. Minor/Significance Unknown.
clonidine
reishi increases effects of clonidine by pharmacodynamic synergism. Minor/Significance Unknown.
cyclopenthiazide
reishi increases effects of cyclopenthiazide by pharmacodynamic synergism. Minor/Significance Unknown.
danshen
danshen and reishi both increase anticoagulation. Minor/Significance Unknown.
devil's claw
devil's claw and reishi both increase anticoagulation. Minor/Significance Unknown.
diltiazem
reishi increases effects of diltiazem by pharmacodynamic synergism. Minor/Significance Unknown.
drospirenone
reishi increases effects of drospirenone by pharmacodynamic synergism. Minor/Significance Unknown.
enalapril
reishi increases effects of enalapril by pharmacodynamic synergism. Minor/Significance Unknown.
eplerenone
reishi increases effects of eplerenone by pharmacodynamic synergism. Minor/Significance Unknown.
epoprostenol
reishi increases effects of epoprostenol by pharmacodynamic synergism. Minor/Significance Unknown.
eprosartan
reishi increases effects of eprosartan by pharmacodynamic synergism. Minor/Significance Unknown.
esmolol
reishi increases effects of esmolol by pharmacodynamic synergism. Minor/Significance Unknown.
ethacrynic acid
reishi increases effects of ethacrynic acid by pharmacodynamic synergism. Minor/Significance Unknown.
felodipine
reishi increases effects of felodipine by pharmacodynamic synergism. Minor/Significance Unknown.
fenoldopam
reishi increases effects of fenoldopam by pharmacodynamic synergism. Minor/Significance Unknown.
fosinopril
reishi increases effects of fosinopril by pharmacodynamic synergism. Minor/Significance Unknown.
furosemide
reishi increases effects of furosemide by pharmacodynamic synergism. Minor/Significance Unknown.
guanfacine
reishi increases effects of guanfacine by pharmacodynamic synergism. Minor/Significance Unknown.
hydralazine
reishi increases effects of hydralazine by pharmacodynamic synergism. Minor/Significance Unknown.
hydrochlorothiazide
reishi increases effects of hydrochlorothiazide by pharmacodynamic synergism. Minor/Significance Unknown.
iloprost
reishi increases effects of iloprost by pharmacodynamic synergism. Minor/Significance Unknown.
imidapril
reishi increases effects of imidapril by pharmacodynamic synergism. Minor/Significance Unknown.
indapamide
reishi increases effects of indapamide by pharmacodynamic synergism. Minor/Significance Unknown.
irbesartan
reishi increases effects of irbesartan by pharmacodynamic synergism. Minor/Significance Unknown.
isradipine
reishi increases effects of isradipine by pharmacodynamic synergism. Minor/Significance Unknown.
ketanserin
reishi increases effects of ketanserin by pharmacodynamic synergism. Minor/Significance Unknown.
labetalol
reishi increases effects of labetalol by pharmacodynamic synergism. Minor/Significance Unknown.
lisinopril
reishi increases effects of lisinopril by pharmacodynamic synergism. Minor/Significance Unknown.
losartan
reishi increases effects of losartan by pharmacodynamic synergism. Minor/Significance Unknown.
mecamylamine
reishi increases effects of mecamylamine by pharmacodynamic synergism. Minor/Significance Unknown.
methyclothiazide
reishi increases effects of methyclothiazide by pharmacodynamic synergism. Minor/Significance Unknown.
metolazone
reishi increases effects of metolazone by pharmacodynamic synergism. Minor/Significance Unknown.
metoprolol
reishi increases effects of metoprolol by pharmacodynamic synergism. Minor/Significance Unknown.
metyrosine
reishi increases effects of metyrosine by pharmacodynamic synergism. Minor/Significance Unknown.
minoxidil
reishi increases effects of minoxidil by pharmacodynamic synergism. Minor/Significance Unknown.
moexipril
reishi increases effects of moexipril by pharmacodynamic synergism. Minor/Significance Unknown.
moxonidine
reishi increases effects of moxonidine by pharmacodynamic synergism. Minor/Significance Unknown.
nadolol
reishi increases effects of nadolol by pharmacodynamic synergism. Minor/Significance Unknown.
nebivolol
reishi increases effects of nebivolol by pharmacodynamic synergism. Minor/Significance Unknown.
nicardipine
reishi increases effects of nicardipine by pharmacodynamic synergism. Minor/Significance Unknown.
nifedipine
reishi increases effects of nifedipine by pharmacodynamic synergism. Minor/Significance Unknown.
nisoldipine
reishi increases effects of nisoldipine by pharmacodynamic synergism. Minor/Significance Unknown.
olmesartan
reishi increases effects of olmesartan by pharmacodynamic synergism. Minor/Significance Unknown.
penbutolol
reishi increases effects of penbutolol by pharmacodynamic synergism. Minor/Significance Unknown.
perindopril
reishi increases effects of perindopril by pharmacodynamic synergism. Minor/Significance Unknown.
pindolol
reishi increases effects of pindolol by pharmacodynamic synergism. Minor/Significance Unknown.
propranolol
reishi increases effects of propranolol by pharmacodynamic synergism. Minor/Significance Unknown.
quinapril
reishi increases effects of quinapril by pharmacodynamic synergism. Minor/Significance Unknown.
ramipril
reishi increases effects of ramipril by pharmacodynamic synergism. Minor/Significance Unknown.
sacubitril/valsartan
reishi increases effects of sacubitril/valsartan by pharmacodynamic synergism. Minor/Significance Unknown.
sotalol
reishi increases effects of sotalol by pharmacodynamic synergism. Minor/Significance Unknown.
spironolactone
reishi increases effects of spironolactone by pharmacodynamic synergism. Minor/Significance Unknown.
telmisartan
reishi increases effects of telmisartan by pharmacodynamic synergism. Minor/Significance Unknown.
timolol
reishi increases effects of timolol by pharmacodynamic synergism. Minor/Significance Unknown.
torsemide
reishi increases effects of torsemide by pharmacodynamic synergism. Minor/Significance Unknown.
trandolapril
reishi increases effects of trandolapril by pharmacodynamic synergism. Minor/Significance Unknown.
treprostinil
reishi increases effects of treprostinil by pharmacodynamic synergism. Minor/Significance Unknown.
triamterene
reishi increases effects of triamterene by pharmacodynamic synergism. Minor/Significance Unknown.
valsartan
reishi increases effects of valsartan by pharmacodynamic synergism. Minor/Significance Unknown.
verapamil
reishi increases effects of verapamil by pharmacodynamic synergism. Minor/Significance Unknown.

acebutolol
Minor (1)reishi increases effects of acebutolol by pharmacodynamic synergism. Minor/Significance Unknown.
aceclofenac
Monitor Closely (1)aceclofenac and reishi both increase anticoagulation. Use Caution/Monitor.
acemetacin
Monitor Closely (1)acemetacin and reishi both increase anticoagulation. Use Caution/Monitor.
agrimony
Monitor Closely (1)agrimony and reishi both increase anticoagulation. Use Caution/Monitor.
alfalfa
Monitor Closely (1)alfalfa and reishi both increase anticoagulation. Use Caution/Monitor.
alteplase
Monitor Closely (1)alteplase and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
American ginseng
Monitor Closely (1)American ginseng and reishi both increase anticoagulation. Use Caution/Monitor.
amiloride
Minor (1)reishi increases effects of amiloride by pharmacodynamic synergism. Minor/Significance Unknown.
amlodipine
Minor (1)reishi increases effects of amlodipine by pharmacodynamic synergism. Minor/Significance Unknown.
anamu
Minor (1)anamu and reishi both increase anticoagulation. Minor/Significance Unknown.
antithrombin alfa
Monitor Closely (1)antithrombin alfa and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
antithrombin III
Monitor Closely (1)antithrombin III and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
argatroban
Monitor Closely (1)argatroban and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
aspirin
Monitor Closely (1)aspirin and reishi both increase anticoagulation. Use Caution/Monitor.
aspirin rectal
Monitor Closely (1)aspirin rectal and reishi both increase anticoagulation. Use Caution/Monitor.
aspirin/citric acid/sodium bicarbonate
Monitor Closely (1)aspirin/citric acid/sodium bicarbonate and reishi both increase anticoagulation. Use Caution/Monitor.
atenolol
Minor (1)reishi increases effects of atenolol by pharmacodynamic synergism. Minor/Significance Unknown.
bemiparin
Monitor Closely (1)bemiparin and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
benazepril
Minor (1)reishi increases effects of benazepril by pharmacodynamic synergism. Minor/Significance Unknown. Enhanced hypotensive and hypoglycemic effects.
bendroflumethiazide
Minor (1)reishi increases effects of bendroflumethiazide by pharmacodynamic synergism. Minor/Significance Unknown.
betaxolol
Minor (1)reishi increases effects of betaxolol by pharmacodynamic synergism. Minor/Significance Unknown.
bisoprolol
Minor (1)reishi increases effects of bisoprolol by pharmacodynamic synergism. Minor/Significance Unknown.
bivalirudin
Monitor Closely (1)bivalirudin and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
bosentan
Minor (1)reishi increases effects of bosentan by pharmacodynamic synergism. Minor/Significance Unknown.
bumetanide
Minor (1)reishi increases effects of bumetanide by pharmacodynamic synergism. Minor/Significance Unknown.
candesartan
Minor (1)reishi increases effects of candesartan by pharmacodynamic synergism. Minor/Significance Unknown.
captopril
Minor (1)reishi increases effects of captopril by pharmacodynamic synergism. Minor/Significance Unknown.
carvedilol
Minor (1)reishi increases effects of carvedilol by pharmacodynamic synergism. Minor/Significance Unknown.
celecoxib
Monitor Closely (1)celecoxib and reishi both increase anticoagulation. Use Caution/Monitor.
celiprolol
Minor (1)reishi increases effects of celiprolol by pharmacodynamic synergism. Minor/Significance Unknown.
chlorothiazide
Minor (1)reishi increases effects of chlorothiazide by pharmacodynamic synergism. Minor/Significance Unknown.
chlorthalidone
Minor (1)reishi increases effects of chlorthalidone by pharmacodynamic synergism. Minor/Significance Unknown.
choline magnesium trisalicylate
Monitor Closely (1)choline magnesium trisalicylate and reishi both increase anticoagulation. Use Caution/Monitor.
cinnamon
Monitor Closely (1)cinnamon and reishi both increase anticoagulation. Use Caution/Monitor.
clevidipine
Minor (1)reishi increases effects of clevidipine by pharmacodynamic synergism. Minor/Significance Unknown.
clonidine
Minor (1)reishi increases effects of clonidine by pharmacodynamic synergism. Minor/Significance Unknown.
cordyceps
Monitor Closely (1)cordyceps and reishi both increase anticoagulation. Use Caution/Monitor.
cyclopenthiazide
Minor (1)reishi increases effects of cyclopenthiazide by pharmacodynamic synergism. Minor/Significance Unknown.
dabigatran
Monitor Closely (1)dabigatran and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
dalteparin
Monitor Closely (1)dalteparin and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
danshen
Minor (1)danshen and reishi both increase anticoagulation. Minor/Significance Unknown.
devil's claw
Minor (1)devil's claw and reishi both increase anticoagulation. Minor/Significance Unknown.
diclofenac
Monitor Closely (1)diclofenac and reishi both increase anticoagulation. Use Caution/Monitor.
diflunisal
Monitor Closely (1)diflunisal and reishi both increase anticoagulation. Use Caution/Monitor.
diltiazem
Minor (1)reishi increases effects of diltiazem by pharmacodynamic synergism. Minor/Significance Unknown.
dong quai
Monitor Closely (1)dong quai and reishi both increase anticoagulation. Use Caution/Monitor.
drospirenone
Minor (1)reishi increases effects of drospirenone by pharmacodynamic synergism. Minor/Significance Unknown.
enalapril
Minor (1)reishi increases effects of enalapril by pharmacodynamic synergism. Minor/Significance Unknown.
enoxaparin
Monitor Closely (1)enoxaparin and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
eplerenone
Minor (1)reishi increases effects of eplerenone by pharmacodynamic synergism. Minor/Significance Unknown.
epoprostenol
Monitor Closely (1)epoprostenol and reishi both increase anticoagulation. Use Caution/Monitor.Minor (1)reishi increases effects of epoprostenol by pharmacodynamic synergism. Minor/Significance Unknown.
eprosartan
Minor (1)reishi increases effects of eprosartan by pharmacodynamic synergism. Minor/Significance Unknown.
esmolol
Minor (1)reishi increases effects of esmolol by pharmacodynamic synergism. Minor/Significance Unknown.
ethacrynic acid
Minor (1)reishi increases effects of ethacrynic acid by pharmacodynamic synergism. Minor/Significance Unknown.
etodolac
Monitor Closely (1)etodolac and reishi both increase anticoagulation. Use Caution/Monitor.
felodipine
Minor (1)reishi increases effects of felodipine by pharmacodynamic synergism. Minor/Significance Unknown.
fennel
Monitor Closely (1)fennel and reishi both increase anticoagulation. Use Caution/Monitor.
fenoldopam
Minor (1)reishi increases effects of fenoldopam by pharmacodynamic synergism. Minor/Significance Unknown.
fenoprofen
Monitor Closely (1)fenoprofen and reishi both increase anticoagulation. Use Caution/Monitor.
feverfew
Monitor Closely (1)feverfew and reishi both increase anticoagulation. Use Caution/Monitor.
flurbiprofen
Monitor Closely (1)flurbiprofen and reishi both increase anticoagulation. Use Caution/Monitor.
fondaparinux
Monitor Closely (1)fondaparinux and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
forskolin
Monitor Closely (1)forskolin and reishi both increase anticoagulation. Use Caution/Monitor.
fosinopril
Minor (1)reishi increases effects of fosinopril by pharmacodynamic synergism. Minor/Significance Unknown.
furosemide
Minor (1)reishi increases effects of furosemide by pharmacodynamic synergism. Minor/Significance Unknown.
garlic
Monitor Closely (1)garlic and reishi both increase anticoagulation. Use Caution/Monitor.
ginger
Monitor Closely (1)ginger and reishi both increase anticoagulation. Use Caution/Monitor.
ginkgo biloba
Monitor Closely (1)ginkgo biloba and reishi both increase anticoagulation. Use Caution/Monitor.
guanfacine
Minor (1)reishi increases effects of guanfacine by pharmacodynamic synergism. Minor/Significance Unknown.
heparin
Monitor Closely (1)heparin and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
horse chestnut seed
Monitor Closely (1)horse chestnut seed and reishi both increase anticoagulation. Use Caution/Monitor.
hydralazine
Minor (1)reishi increases effects of hydralazine by pharmacodynamic synergism. Minor/Significance Unknown.
hydrochlorothiazide
Minor (1)reishi increases effects of hydrochlorothiazide by pharmacodynamic synergism. Minor/Significance Unknown.
ibuprofen
Monitor Closely (1)ibuprofen and reishi both increase anticoagulation. Use Caution/Monitor.
ibuprofen IV
Monitor Closely (1)ibuprofen IV and reishi both increase anticoagulation. Use Caution/Monitor.
iloprost
Minor (1)reishi increases effects of iloprost by pharmacodynamic synergism. Minor/Significance Unknown.
imidapril
Minor (1)reishi increases effects of imidapril by pharmacodynamic synergism. Minor/Significance Unknown.
indapamide
Minor (1)reishi increases effects of indapamide by pharmacodynamic synergism. Minor/Significance Unknown.
indomethacin
Monitor Closely (1)indomethacin and reishi both increase anticoagulation. Use Caution/Monitor.
irbesartan
Minor (1)reishi increases effects of irbesartan by pharmacodynamic synergism. Minor/Significance Unknown.
isradipine
Minor (1)reishi increases effects of isradipine by pharmacodynamic synergism. Minor/Significance Unknown.
ketanserin
Minor (1)reishi increases effects of ketanserin by pharmacodynamic synergism. Minor/Significance Unknown.
ketoprofen
Monitor Closely (1)ketoprofen and reishi both increase anticoagulation. Use Caution/Monitor.
ketorolac
Monitor Closely (1)ketorolac and reishi both increase anticoagulation. Use Caution/Monitor.
ketorolac intranasal
Monitor Closely (1)ketorolac intranasal and reishi both increase anticoagulation. Use Caution/Monitor.
labetalol
Minor (1)reishi increases effects of labetalol by pharmacodynamic synergism. Minor/Significance Unknown.
lisinopril
Minor (1)reishi increases effects of lisinopril by pharmacodynamic synergism. Minor/Significance Unknown.
lornoxicam
Monitor Closely (1)lornoxicam and reishi both increase anticoagulation. Use Caution/Monitor.
losartan
Minor (1)reishi increases effects of losartan by pharmacodynamic synergism. Minor/Significance Unknown.
mecamylamine
Minor (1)reishi increases effects of mecamylamine by pharmacodynamic synergism. Minor/Significance Unknown.
meclofenamate
Monitor Closely (1)meclofenamate and reishi both increase anticoagulation. Use Caution/Monitor.
mefenamic acid
Monitor Closely (1)mefenamic acid and reishi both increase anticoagulation. Use Caution/Monitor.
meloxicam
Monitor Closely (1)meloxicam and reishi both increase anticoagulation. Use Caution/Monitor.
methyclothiazide
Minor (1)reishi increases effects of methyclothiazide by pharmacodynamic synergism. Minor/Significance Unknown.
metolazone
Minor (1)reishi increases effects of metolazone by pharmacodynamic synergism. Minor/Significance Unknown.
metoprolol
Minor (1)reishi increases effects of metoprolol by pharmacodynamic synergism. Minor/Significance Unknown.
metyrosine
Minor (1)reishi increases effects of metyrosine by pharmacodynamic synergism. Minor/Significance Unknown.
minoxidil
Minor (1)reishi increases effects of minoxidil by pharmacodynamic synergism. Minor/Significance Unknown.
mistletoe
Monitor Closely (1)reishi increases and mistletoe decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.
moexipril
Minor (1)reishi increases effects of moexipril by pharmacodynamic synergism. Minor/Significance Unknown.
moxonidine
Minor (1)reishi increases effects of moxonidine by pharmacodynamic synergism. Minor/Significance Unknown.
nabumetone
Monitor Closely (1)nabumetone and reishi both increase anticoagulation. Use Caution/Monitor.
nadolol
Minor (1)reishi increases effects of nadolol by pharmacodynamic synergism. Minor/Significance Unknown.
naproxen
Monitor Closely (1)naproxen and reishi both increase anticoagulation. Use Caution/Monitor.
nebivolol
Minor (1)reishi increases effects of nebivolol by pharmacodynamic synergism. Minor/Significance Unknown.
nettle
Monitor Closely (1)reishi increases and nettle decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.
nicardipine
Minor (1)reishi increases effects of nicardipine by pharmacodynamic synergism. Minor/Significance Unknown.
nifedipine
Minor (1)reishi increases effects of nifedipine by pharmacodynamic synergism. Minor/Significance Unknown.
nisoldipine
Minor (1)reishi increases effects of nisoldipine by pharmacodynamic synergism. Minor/Significance Unknown.
olmesartan
Minor (1)reishi increases effects of olmesartan by pharmacodynamic synergism. Minor/Significance Unknown.
oxaprozin
Monitor Closely (1)oxaprozin and reishi both increase anticoagulation. Use Caution/Monitor.
panax ginseng
Monitor Closely (1)panax ginseng and reishi both increase anticoagulation. Use Caution/Monitor.
parecoxib
Monitor Closely (1)parecoxib and reishi both increase anticoagulation. Use Caution/Monitor.
pau d'arco
Monitor Closely (1)pau d'arco and reishi both increase anticoagulation. Use Caution/Monitor.
penbutolol
Minor (1)reishi increases effects of penbutolol by pharmacodynamic synergism. Minor/Significance Unknown.
perindopril
Minor (1)reishi increases effects of perindopril by pharmacodynamic synergism. Minor/Significance Unknown.
phenindione
Monitor Closely (1)phenindione and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
phytoestrogens
Monitor Closely (1)phytoestrogens and reishi both increase anticoagulation. Use Caution/Monitor.
pindolol
Minor (1)reishi increases effects of pindolol by pharmacodynamic synergism. Minor/Significance Unknown.
piroxicam
Monitor Closely (1)piroxicam and reishi both increase anticoagulation. Use Caution/Monitor.
propranolol
Minor (1)reishi increases effects of propranolol by pharmacodynamic synergism. Minor/Significance Unknown.
protamine
Monitor Closely (1)protamine and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
quinapril
Minor (1)reishi increases effects of quinapril by pharmacodynamic synergism. Minor/Significance Unknown.
ramipril
Minor (1)reishi increases effects of ramipril by pharmacodynamic synergism. Minor/Significance Unknown.
reteplase
Monitor Closely (1)reteplase and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
sacubitril/valsartan
Minor (1)reishi increases effects of sacubitril/valsartan by pharmacodynamic synergism. Minor/Significance Unknown.
salicylates (non-asa)
Monitor Closely (1)salicylates (non-asa) and reishi both increase anticoagulation. Use Caution/Monitor.
salsalate
Monitor Closely (1)salsalate and reishi both increase anticoagulation. Use Caution/Monitor.
Siberian ginseng
Monitor Closely (1)reishi and Siberian ginseng both increase anticoagulation. Use Caution/Monitor.
sotalol
Minor (1)reishi increases effects of sotalol by pharmacodynamic synergism. Minor/Significance Unknown.
spironolactone
Minor (1)reishi increases effects of spironolactone by pharmacodynamic synergism. Minor/Significance Unknown.
sulfasalazine
Monitor Closely (1)sulfasalazine and reishi both increase anticoagulation. Use Caution/Monitor.
sulindac
Monitor Closely (1)sulindac and reishi both increase anticoagulation. Use Caution/Monitor.
telmisartan
Minor (1)reishi increases effects of telmisartan by pharmacodynamic synergism. Minor/Significance Unknown.
tenecteplase
Monitor Closely (1)tenecteplase and reishi both increase anticoagulation. Modify Therapy/Monitor Closely.
timolol
Minor (1)reishi increases effects of timolol by pharmacodynamic synergism. Minor/Significance Unknown.
tolfenamic acid
Monitor Closely (1)tolfenamic acid and reishi both increase anticoagulation. Use Caution/Monitor.
tolmetin
Monitor Closely (1)tolmetin and reishi both increase anticoagulation. Use Caution/Monitor.
torsemide
Minor (1)reishi increases effects of torsemide by pharmacodynamic synergism. Minor/Significance Unknown.
trandolapril
Minor (1)reishi increases effects of trandolapril by pharmacodynamic synergism. Minor/Significance Unknown.
treprostinil
Minor (1)reishi increases effects of treprostinil by pharmacodynamic synergism. Minor/Significance Unknown.
triamterene
Minor (1)reishi increases effects of triamterene by pharmacodynamic synergism. Minor/Significance Unknown.
valsartan
Minor (1)reishi increases effects of valsartan by pharmacodynamic synergism. Minor/Significance Unknown.
verapamil
Minor (1)reishi increases effects of verapamil by pharmacodynamic synergism. Minor/Significance Unknown.
vitamin K1 (phytonadione)
Monitor Closely (1)reishi increases and vitamin K1 (phytonadione) decreases anticoagulation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

Adverse Effects

None reported

Contraindications

Concurrency with other anticoagulant medications

Cautions

Continuous use for 3-6 months may cause dizziness, dry mouth, nose bleeds, & upset stomach

Commercial preparations may vary in strength, check Mfr's label

Pregnancy & Lactation

Pregnancy Category: check with physician

Lactation: check with physician

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Pharmacology

Metabolism: N/A

Excretion: N/A

Mechanism of Action

See efficacy

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

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Sections Reishi
Suggested Dosing
Suggested Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology

Reishi (Herb/Suppl)