Dosing & Uses
Dosage Forms & Strengths
cream/ointment
- 1%
Gram-Negative Infections
Topical: Apply to affected area q6-8hr
Dosage Forms & Strengths
cream/ointment
- 1%
Gram-Negative Infections
> 1year: Apply to affected area q6-8hr
Adverse Effects
Frequency Not Defined
Allergic contact dermatitis
Erythema
Pruritus
Warnings
Contraindications
Hypersensitivity
Skin rash
Cautions
Prolonged use may result in bacterial or fungal superinfection; discontinue if superinfection develops
Local redness/irritation reported
Not for long term therapy
Pregnancy & Lactation
Pregnancy Category: C
Lactation: excreted in breast milk; no adverse effect on nursing infant
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Bactericidal; appears to inhibit protein synthesis in susceptible bacteria by irreversibly binding to 30S and 50S ribosomal subunits
Pharmacokinetics
Absorption: Systemic absorption reported in burn patients treated with topical gentamicin
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Formulary
Adding plans allows you to compare formulary status to other drugs in the same class.
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Adding plans allows you to:
- View the formulary and any restrictions for each plan.
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- Compare formulary status to other drugs in the same class.
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