Germanium (Herb/Suppl)

Brand and Other Names:
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Suggested Dosing

Follow Mfr's instructions

Not considered safe

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Suggested Uses

Cancers

Efficacy

Unproven, may be harmful

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Interactions

Interaction Checker

and Germanium

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Contraindicated (0)

              Serious - Use Alternative (1)

              • fluorouracil

                germanium increases toxicity of fluorouracil by unspecified interaction mechanism. Contraindicated. Risk of toxicity, death with combination.

              Monitor Closely (0)

                Minor (1)

                • furosemide

                  germanium decreases effects of furosemide by unknown mechanism. Minor/Significance Unknown. Case report.

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                Adverse Effects

                Kidney damage, anemia, appetite loss, nerve/muscle damage, death

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                Warnings

                Contraindications

                Pregnancy, lactation

                Cautions

                Risk of kidney damage, esp with inorganic germanium

                May exacerbate seizures

                Numerous harmful side effects

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                Pregnancy & Lactation

                Pregnancy Category: do not use

                Lactation: do not use

                Pregnancy Categories

                A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                NA: Information not available.

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                Pharmacology

                Metabolism: N/A

                Excretion: N/A

                Mechanism of Action

                Claimed to increase oxygen delivery to cells

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                Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.