Maitake (Herb/Suppl)

Brand and Other Names:grifola frondosa
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Suggested Dosing

Medicinal mushroom extract (liquid, tablet, capsule) 3-7.0 g/d PO

Maitake mushrooms: may be consumed as food or made into tea

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Suggested Uses

Treatment or prevention of cancer

Boosts human immune system & limits or reverses tumor growth

Enhances benefits of chemo & lessens side effects of hair loss, pain, & nausea

Clinical trials currently undergoing study:

to learn if beta glucan can increase effectiveness of rituximab by making cancer cells more sensitive to it

of young patients with relapsed or progressive lymphoma, leukemia, or similar d/o

with other drugs to learn if they increase effectiveness of another monoclonal antibody

for breast cancer treatment; neuroblastoma patients that have not responded to treatment

combining different types of biological treatment

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Interactions

Interaction Checker

and Maitake

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

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             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (46)

                • adalimumab

                  adalimumab increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • alefacept

                  alefacept increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • anakinra

                  anakinra increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • antithymocyte globulin equine

                  antithymocyte globulin equine increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • antithymocyte globulin rabbit

                  antithymocyte globulin rabbit increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • azathioprine

                  azathioprine increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • basiliximab

                  basiliximab increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • bendroflumethiazide

                  maitake increases effects of bendroflumethiazide by pharmacodynamic synergism. Use Caution/Monitor. Increased risk of hypokalemia (theoretical interaction).

                • bumetanide

                  maitake increases effects of bumetanide by pharmacodynamic synergism. Use Caution/Monitor. Increased risk of hypokalemia (theoretical interaction).

                • canakinumab

                  canakinumab increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • candesartan

                  maitake increases effects of candesartan by pharmacodynamic synergism. Use Caution/Monitor.

                • chlorothiazide

                  maitake increases effects of chlorothiazide by pharmacodynamic synergism. Use Caution/Monitor. Increased risk of hypokalemia (theoretical interaction).

                • chlorthalidone

                  maitake increases effects of chlorthalidone by pharmacodynamic synergism. Use Caution/Monitor. Increased risk of hypokalemia (theoretical interaction).

                • cyclopenthiazide

                  maitake increases effects of cyclopenthiazide by pharmacodynamic synergism. Use Caution/Monitor. Increased risk of hypokalemia (theoretical interaction).

                • eprosartan

                  maitake increases effects of eprosartan by pharmacodynamic synergism. Use Caution/Monitor.

                • etanercept

                  etanercept increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • ethacrynic acid

                  maitake increases effects of ethacrynic acid by pharmacodynamic synergism. Use Caution/Monitor. Increased risk of hypokalemia (theoretical interaction).

                • everolimus

                  everolimus increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • furosemide

                  maitake increases effects of furosemide by pharmacodynamic synergism. Use Caution/Monitor. Increased risk of hypokalemia (theoretical interaction).

                • glatiramer

                  glatiramer increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • golimumab

                  golimumab increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • hydrochlorothiazide

                  maitake increases effects of hydrochlorothiazide by pharmacodynamic synergism. Use Caution/Monitor. Increased risk of hypokalemia (theoretical interaction).

                • hydroxychloroquine sulfate

                  hydroxychloroquine sulfate increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • indapamide

                  maitake increases effects of indapamide by pharmacodynamic synergism. Use Caution/Monitor. Increased risk of hypokalemia (theoretical interaction).

                • infliximab

                  infliximab increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • irbesartan

                  maitake increases effects of irbesartan by pharmacodynamic synergism. Use Caution/Monitor.

                • leflunomide

                  leflunomide increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • losartan

                  maitake increases effects of losartan by pharmacodynamic synergism. Use Caution/Monitor.

                • mercaptopurine

                  mercaptopurine increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • methotrexate

                  methotrexate increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • methyclothiazide

                  maitake increases effects of methyclothiazide by pharmacodynamic synergism. Use Caution/Monitor. Increased risk of hypokalemia (theoretical interaction).

                • metolazone

                  maitake increases effects of metolazone by pharmacodynamic synergism. Use Caution/Monitor. Increased risk of hypokalemia (theoretical interaction).

                • muromonab CD3

                  muromonab CD3 increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • mycophenolate

                  mycophenolate increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • olmesartan

                  maitake increases effects of olmesartan by pharmacodynamic synergism. Use Caution/Monitor.

                • rilonacept

                  rilonacept increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • sacubitril/valsartan

                  maitake increases effects of sacubitril/valsartan by pharmacodynamic synergism. Use Caution/Monitor.

                • sirolimus

                  sirolimus increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • tacrolimus

                  tacrolimus increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • telmisartan

                  maitake increases effects of telmisartan by pharmacodynamic synergism. Use Caution/Monitor.

                • temsirolimus

                  temsirolimus increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • tocilizumab

                  tocilizumab increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor. .

                • tongkat ali

                  tongkat ali increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • torsemide

                  maitake increases effects of torsemide by pharmacodynamic synergism. Use Caution/Monitor. Increased risk of hypokalemia (theoretical interaction).

                • ustekinumab

                  ustekinumab increases and maitake decreases immunosuppressive effects; risk of infection. Effect of interaction is not clear, use caution. Use Caution/Monitor.

                • valsartan

                  maitake increases effects of valsartan by pharmacodynamic synergism. Use Caution/Monitor.

                Minor (113)

                • acarbose

                  maitake increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • acebutolol

                  maitake increases effects of acebutolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • amiloride

                  maitake increases effects of amiloride by pharmacodynamic synergism. Minor/Significance Unknown.

                • amlodipine

                  maitake increases effects of amlodipine by pharmacodynamic synergism. Minor/Significance Unknown.

                • astragalus

                  astragalus and maitake both decrease immunosuppressive effects; risk of infection. Minor/Significance Unknown.

                • atenolol

                  maitake increases effects of atenolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • benazepril

                  maitake increases effects of benazepril by pharmacodynamic synergism. Minor/Significance Unknown. Additive hypotensive effects.

                • betaxolol

                  maitake increases effects of betaxolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • bicalutamide

                  maitake increases effects of bicalutamide by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • bisoprolol

                  maitake increases effects of bisoprolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • bosentan

                  maitake increases effects of bosentan by pharmacodynamic synergism. Minor/Significance Unknown.

                • capecitabine

                  maitake increases effects of capecitabine by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • captopril

                  maitake increases effects of captopril by pharmacodynamic synergism. Minor/Significance Unknown. Both drugs decrease blood glucose and blood pressure. Monitor blood glucose and blood pressure.

                • carvedilol

                  maitake increases effects of carvedilol by pharmacodynamic synergism. Minor/Significance Unknown.

                • celiprolol

                  maitake increases effects of celiprolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • chlorpropamide

                  maitake increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • cladribine

                  maitake increases effects of cladribine by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • clevidipine

                  maitake increases effects of clevidipine by pharmacodynamic synergism. Minor/Significance Unknown.

                • clonidine

                  maitake increases effects of clonidine by pharmacodynamic synergism. Minor/Significance Unknown.

                • cytarabine

                  maitake increases effects of cytarabine by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • decitabine

                  maitake increases effects of decitabine by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • diltiazem

                  maitake increases effects of diltiazem by pharmacodynamic synergism. Minor/Significance Unknown.

                • docetaxel

                  maitake increases effects of docetaxel by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • drospirenone

                  maitake increases effects of drospirenone by pharmacodynamic synergism. Minor/Significance Unknown.

                • echinacea

                  echinacea and maitake both decrease immunosuppressive effects; risk of infection. Minor/Significance Unknown.

                • enalapril

                  maitake increases effects of enalapril by pharmacodynamic synergism. Minor/Significance Unknown.

                • eplerenone

                  maitake increases effects of eplerenone by pharmacodynamic synergism. Minor/Significance Unknown.

                • epoprostenol

                  maitake increases effects of epoprostenol by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • esmolol

                  maitake increases effects of esmolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • felodipine

                  maitake increases effects of felodipine by pharmacodynamic synergism. Minor/Significance Unknown.

                • fenoldopam

                  maitake increases effects of fenoldopam by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • floxuridine

                  maitake increases effects of floxuridine by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • fludarabine

                  maitake increases effects of fludarabine by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • fluorouracil

                  maitake increases effects of fluorouracil by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • flutamide

                  maitake increases effects of flutamide by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • fosinopril

                  maitake increases effects of fosinopril by pharmacodynamic synergism. Minor/Significance Unknown.

                • fulvestrant

                  maitake increases effects of fulvestrant by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • gemcitabine

                  maitake increases effects of gemcitabine by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • glimepiride

                  maitake increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • glipizide

                  maitake increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • glyburide

                  maitake increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • goserelin

                  maitake increases effects of goserelin by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • guanfacine

                  maitake increases effects of guanfacine by pharmacodynamic synergism. Minor/Significance Unknown.

                • hydralazine

                  maitake increases effects of hydralazine by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • iloprost

                  maitake increases effects of iloprost by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • imidapril

                  maitake increases effects of imidapril by pharmacodynamic synergism. Minor/Significance Unknown.

                • insulin aspart

                  maitake increases effects of insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • insulin detemir

                  maitake increases effects of insulin detemir by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • insulin glargine

                  maitake increases effects of insulin glargine by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • insulin glulisine

                  maitake increases effects of insulin glulisine by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • insulin lispro

                  maitake increases effects of insulin lispro by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • insulin NPH

                  maitake increases effects of insulin NPH by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • insulin regular human

                  maitake increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • isradipine

                  maitake increases effects of isradipine by pharmacodynamic synergism. Minor/Significance Unknown.

                • ketanserin

                  maitake increases effects of ketanserin by pharmacodynamic synergism. Minor/Significance Unknown.

                • labetalol

                  maitake increases effects of labetalol by pharmacodynamic synergism. Minor/Significance Unknown.

                • leuprolide

                  maitake increases effects of leuprolide by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • lisinopril

                  maitake increases effects of lisinopril by pharmacodynamic synergism. Minor/Significance Unknown.

                • mecamylamine

                  maitake increases effects of mecamylamine by pharmacodynamic synergism. Minor/Significance Unknown.

                • medroxyprogesterone

                  maitake increases effects of medroxyprogesterone by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • megestrol

                  maitake increases effects of megestrol by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • mercaptopurine

                  maitake increases effects of mercaptopurine by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • metformin

                  maitake increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • methotrexate

                  maitake increases effects of methotrexate by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • metoprolol

                  maitake increases effects of metoprolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • metyrosine

                  maitake increases effects of metyrosine by pharmacodynamic synergism. Minor/Significance Unknown.

                • miglitol

                  maitake increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • minoxidil

                  maitake increases effects of minoxidil by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • moexipril

                  maitake increases effects of moexipril by pharmacodynamic synergism. Minor/Significance Unknown.

                • moxonidine

                  maitake increases effects of moxonidine by pharmacodynamic synergism. Minor/Significance Unknown.

                • nadolol

                  maitake increases effects of nadolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • nateglinide

                  maitake increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • nebivolol

                  maitake increases effects of nebivolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • nelarabine

                  maitake increases effects of nelarabine by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • nicardipine

                  maitake increases effects of nicardipine by pharmacodynamic synergism. Minor/Significance Unknown.

                • nifedipine

                  maitake increases effects of nifedipine by pharmacodynamic synergism. Minor/Significance Unknown.

                • nilutamide

                  maitake increases effects of nilutamide by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • nisoldipine

                  maitake increases effects of nisoldipine by pharmacodynamic synergism. Minor/Significance Unknown.

                • oxaliplatin

                  maitake increases effects of oxaliplatin by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • paclitaxel

                  maitake increases effects of paclitaxel by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • paclitaxel protein bound

                  maitake increases effects of paclitaxel protein bound by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • penbutolol

                  maitake increases effects of penbutolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • pentostatin

                  maitake increases effects of pentostatin by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • perindopril

                  maitake increases effects of perindopril by pharmacodynamic synergism. Minor/Significance Unknown.

                • pindolol

                  maitake increases effects of pindolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • pioglitazone

                  maitake increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • pralatrexate

                  maitake increases effects of pralatrexate by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • propranolol

                  maitake increases effects of propranolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • quinapril

                  maitake increases effects of quinapril by pharmacodynamic synergism. Minor/Significance Unknown.

                • ramipril

                  maitake increases effects of ramipril by pharmacodynamic synergism. Minor/Significance Unknown.

                • repaglinide

                  maitake increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • rosiglitazone

                  maitake increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • saxagliptin

                  maitake increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • sitagliptin

                  maitake increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • sotalol

                  maitake increases effects of sotalol by pharmacodynamic synergism. Minor/Significance Unknown.

                • spironolactone

                  maitake increases effects of spironolactone by pharmacodynamic synergism. Minor/Significance Unknown.

                • tamoxifen

                  maitake increases effects of tamoxifen by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • thioguanine

                  maitake increases effects of thioguanine by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • timolol

                  maitake increases effects of timolol by pharmacodynamic synergism. Minor/Significance Unknown.

                • tolazamide

                  maitake increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • tolbutamide

                  maitake increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • toremifene

                  maitake increases effects of toremifene by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • trandolapril

                  maitake increases effects of trandolapril by pharmacodynamic synergism. Minor/Significance Unknown.

                • treosulfan

                  maitake increases effects of treosulfan by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • treprostinil

                  maitake increases effects of treprostinil by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • triamterene

                  maitake increases effects of triamterene by pharmacodynamic synergism. Minor/Significance Unknown.

                • triptorelin

                  maitake increases effects of triptorelin by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • verapamil

                  maitake increases effects of verapamil by pharmacodynamic synergism. Minor/Significance Unknown.

                • vildagliptin

                  maitake increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of hypoglycemia (animal research).

                • vinblastine

                  maitake increases effects of vinblastine by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • vincristine

                  maitake increases effects of vincristine by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • vincristine liposomal

                  maitake increases effects of vincristine liposomal by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

                • vinorelbine

                  maitake increases effects of vinorelbine by pharmacodynamic synergism. Minor/Significance Unknown. Maitake mushroom has anti-tumor effects (animal/in vitro research).

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                Adverse Effects

                None reported

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                Warnings

                Cautions

                Commercial preparations may vary in strength, check Mfr's label

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                Pregnancy & Lactation

                Pregnancy Category: check with physician

                Lactation: check with physician

                Pregnancy Categories

                A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                NA: Information not available.

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                Pharmacology

                Metabolism: N/A

                Excretion: N/A

                Mechanism of Action

                Maitake D-fraction contains a polysaccharide called beta-glucan believed to stimulate & activate certain immune cells & proteins that attack cancer cells: macrophages, T-cellls, natural killer cells, & interleukin 1 & 2

                Efficacy:

                • Current clinical trials undergoing study
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                Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.